Results 81 to 90 of about 3,341,597 (311)

Steps toward broad-spectrum therapeutics : discovering virulence-associated genes present in diverse human pathogens [PDF]

, 2009
© 2009 Stubben et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and ...
Gans, Jason D, Wolinsky Murray, Cooper, Ian A, Karlyshev, Andrey, Wren, Brendan W, Cooper Ian A, Duffield Melanie L, Ford Donna C, Lingard, Bryan, Ford, Donna C, Oyston, Petra CF, Karlyshev, Andrey V, Titball, Rick W, Lingard, Brian, Duffield, Melanie L, Karlyshev Andrey V, Gans Jason D, Oyston Petra CF, Song, Jian, Stubben, Chris J, Oyston, Petra C F, Titball Rick W, de Rochefort Anna, Stubben Chris J, Wren Brendan W, Lingard Bryan, Wolinsky, Murray, de Rochefort, Anna, Song Jian, Murray Wolinsky, Jason D Gans, Rick W Titball, Brendan W Wren, Donna C Ford, Ian A Cooper, Melanie L Duffield, Andrey V Karlyshev, Petra CF Oyston, Bryan Lingard, Anna de Rochefort, Chris J Stubben, Jian Song   +41 more
core   +1 more source

Distribution and diversity of bacterial secretion systems across metagenomic datasets [PDF]

, 2012
Bacteria can manipulate their surrounding environment through the secretion of proteins into other living organisms and into the extracellular milieu. In Gram stain negative bacteria this process is mediated by different types of secretion systems from ...
Egan, F., Barret, M., O'Gara, Fergal, Egan, Frank, O’Gara, Fergal, Barret, Matthieu   +5 more
core   +2 more sources

Chitosan-based structures for targeting bacterial biofilm-associated genes

Carbohydrate Polymer Technologies and Applications
Biofilms are a common lifestyle, in which bacteria grow as multicellular communities. The negative consequences of biofilms are well known. The targeted suppression of certain genes is a promising approach for combating biofilms. Chitosan (CS) has become
Shima Afrasiabi
doaj   +1 more source

Bacteria under SOS evolve anticancer phenotypes

Infectious Agents and Cancer, 2010
Background The anticancer drugs, such as DNA replication inhibitors, stimulate bacterial adhesion and induce the bacterial SOS response. As a variety of bacterial mutants can be generated during SOS, novel phenotypes are likely to be selected under the ...
Weitao Tao, Dallo Shatha F
doaj   +1 more source

Silicon dioxide nanoparticles have contrasting effects on the temporal dynamics of sulfonamide and β-lactam resistance genes in soils amended with antibiotics

Environmental Research Letters, 2020
Nanoparticles (NPs) and antibiotic resistant genes (ARGs), as emerging environmental contaminants, have been reported to be accumulated in the soil environment.
Xiujuan Zhang, Junjian Li, Dale Li, Hong Zhang, Hangwei Hu   +4 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Genes related to peptidoglycan modifications in the bacterial genome.

, 2023
Genes related to peptidoglycan modifications in the bacterial genome.
Toshitaka Yamauchi (15195380), Hina Kosakamoto (7307417), Takumi Murakami (1562506), Hiroshi Mori (341642), Taro Onuma (15195377), Hibiki Kadoguchi (15195383), Fumiaki Obata (9336620), Takayuki Kuraishi (8627847), Masayuki Miura (185175)   +8 more
core   +1 more source

Targeting bacterial biofilm-related genes with nanoparticle-based strategies

Frontiers in Microbiology
Persistent infection caused by biofilm is an urgent in medicine that should be tackled by new alternative strategies. Low efficiency of classical treatments and antibiotic resistance are the main concerns of the persistent infection due to biofilm ...
Shima Afrasiabi, Alireza Partoazar
doaj   +1 more source

Analysis of differentially expressed genes in bacterial and fungal keratitis

Indian Journal of Ophthalmology, 2020
Purpose: This study was aimed at identifying differentially expressed genes (DEGs) in bacterial and fungal keratitis. The candidate genes can be selected and quantified to distinguish between causative agents of infectious keratitis to improve ...
Rui Tian, He Zou, Lufei Wang, Lu Liu, Meijiao Song, Hui Zhang   +5 more
doaj   +1 more source