Molecular dissection of the mechanism by which EWS/FLI expression compromises actin cytoskeletal integrity and cell adhesion in Ewing sarcoma. [PDF]
, 2014 Ewing sarcoma is the second-most-common bone cancer in children. Driven by an oncogenic chromosomal translocation that results in the expression of an aberrant transcription factor, EWS/FLI, the disease is typically aggressive and micrometastatic upon ...
Beckerle, Mary C +8 more
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Gene Expression Dominance in Allopolyploids: Hypotheses and Models [PDF]
Trends in Plant Science, 2018 The classical example of nonadditive contributions of the two parents to allopolyploids is nucleolar dominance, which entails silencing of one parental set of ribosomal RNA genes. This has been observed for many other loci. The prevailing explanation for this genome-wide expression disparity is that the two merged genomes differ in their transposable ...
Bottani, S +3 more
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Genetic Analysis on Seed Size of Chieh-qua by Mixture Model of Major Genes and Polygenes
Guangdong nongye kexue, 2023 【Objective】Genetic analysis of major gene and polygenes was conducted on the length, width, and quality of Chieh-qua seeds to study the genetic rules of seed size and select high-quality Chieh-qua varieties.【Method】Chieh-qua inbred line J16 (big seed ...
Yin GAO +3 more
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Oakleaf: an S locus-linked mutation of Primula vulgaris that affects leaf and flower development [PDF]
, 2015 •In Primula vulgaris outcrossing is promoted through reciprocal herkogamy with insect-mediated cross-pollination between pin and thrum form flowers. Development of heteromorphic flowers is coordinated by genes at the S locus.
Anders S +19 more
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Characterization and gene expression analysis of the cir multi-gene family of plasmodium chabaudi chabaudi (AS) [PDF]
, 2012 Background: The pir genes comprise the largest multi-gene family in Plasmodium, with members found in P. vivax, P. knowlesi and the rodent malaria species.
Berriman, Matthew +11 more
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The molecular genetic analysis of the expanding pachyonychia congenita case collection [PDF]
, 2014 BACKGROUND: Pachyonychia congenita (PC) is a rare autosomal dominant keratinizing disorder characterized by severe, painful, palmoplantar keratoderma and nail dystrophy, often accompanied by oral leucokeratosis, cysts and follicular keratosis.
Al-Asadi, E. +9 more
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Evaluation of polygenic determinants of non-alcoholic fatty liver disease (NAFLD) by a candidate genes resequencing strategy [PDF]
, 2018 NAFLD is a polygenic condition but the individual and cumulative contribution of identified genes remains to be established. To get additional insight into the genetic architecture of NAFLD, GWAS-identified GCKR, PPP1R3B, NCAN, LYPLAL1 and TM6SF2 genes ...
Angelico F +16 more
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A dominant gene for developmental dyslexia on chromosome 3 [PDF]
Journal of Medical Genetics, 2001 Developmental dyslexia is a neurofunctional disorder characterised by an unexpected difficulty in learning to read and write despite adequate intelligence, motivation, and education. Previous studies have suggested mostly quantitative susceptibility loci for dyslexia on chromosomes 1, 2, 6, and 15, but no genes have been identified yet.
J, Nopola-Hemmi +8 more
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Ecotoxicology and Environmental Safety, 2022 Previous research on antibiotic resistance genes and microorganisms centered on those in urban sewage treatment plants, breeding farms, hospitals and others with serious antibiotic pollution.
Jia Ai +5 more
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Nasal Bacterial Microbiome: Probing a Healthy Porcine Family [PDF]
, 2011 Upper respiratory tract (URT) infection caused the leading and devastating diseases in pigs. It was believed that the normal microbiome of URT plays a vital role in health and disease development.
Huanchun Chen, Min Yue, Weicheng Bei
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