Results 41 to 50 of about 6,532,899 (237)

Nucleolar dominance and ribosomal RNA gene silencing [PDF]

Current Opinion in Cell Biology, 2010
Nucleolar dominance is an epigenetic phenomenon that occurs in genetic hybrids and describes the expression of 45S rRNA genes inherited from one progenitor due to the silencing of the other progenitor's rRNA genes. Nucleolar dominance is a manifestation of rRNA gene dosage control, which also occurs in non-hybrids, regulating the number of active rRNA ...
Sarah Tucker, Alexa Vitins, Craig S. Pikaard, Craig S. Pikaard   +3 more
openaire   +3 more sources

CTCF-mediated transcriptional regulation through cell type-specific chromosome organization in the {\beta}-globin locus [PDF]

, 2012
The principles underlying the architectural landscape of chromatin beyond the nucleosome level in living cells remains largely unknown despite its potential to play a role in mammalian gene regulation. We investigated the 3-dimensional folding of a 1 Mbp
Ann Dean, Bau, Bau, Bender, Bender, Botta, Chunhui Hou, Cook, Cui, de Gennes, Dekker, Dorier, Dostie, Drissen, Duan, Farrell, François Képès, Fraser, Hadjur, Handoko, Hou, Hou, Ivan Junier, Junier, Kalhor, Kiefer, Kim, Krivega, Kurukuti, Langowski, Lee, Lieberman-Aiden, Marenduzzo, Mateos-Langerak, Mukhopadhyay, Murrell, Ong, Palstra, Phillips, Ragoczy, Reuillon, Rosa, Rousseau, Ryan K. Dale, Schoenfelder, Sexton, Sexton, Simonis, Song, Song, Splinter, Stamatoyannopoulos, Strick, Tolhuis, Vakoc, Wallace, Yaffe   +56 more
core   +5 more sources

β-Glucan is a major growth substrate for human gut bacteria related to Coprococcus eutactus [PDF]

, 2020
A clone encoding carboxymethyl cellulase activity was isolated during functional screening of a human gut metagenomic library using Lactococcus lactis MG1363 as heterologous host.
Alessi, Anna M, Collie-Duguid, Elaina S R, Farquharson, Freda M, Flint, Harry J, Flores-López, Adriana, Gasson, Mike, Gray, Victoria, Louis, Petra, Shaw, Sophie, Shearman, Claire, Stead, David, Wegmann, Udo   +11 more
core   +3 more sources

arrEYE : a customized platform for high-resolution copy number analysis of coding and noncoding regions of known and candidate retinal dystrophy genes and retinal noncoding RNAs [PDF]

, 2017
Purpose: Our goal was to design a customized microarray, arrEYE, for high-resolution copy number variant (CNV) analysis of known and candidate genes for inherited retinal dystrophy (iRD) and retina expressed noncoding RNAs (ncRNAs).
Bauwens, Miriam, Cannoodt, Robrecht, Coppieters, Frauke, De Baere, Elfride, De Jaegere, Sarah, Leroy, Bart, Menten, Björn, Sante, Tom, Steyaert, Wouter, Van Cauwenbergh, Caroline, Van Laethem, Thalia, Van Schil, Kristof   +11 more
core   +2 more sources

Evaluation of polygenic determinants of non-alcoholic fatty liver disease (NAFLD) by a candidate genes resequencing strategy [PDF]

, 2018
NAFLD is a polygenic condition but the individual and cumulative contribution of identified genes remains to be established. To get additional insight into the genetic architecture of NAFLD, GWAS-identified GCKR, PPP1R3B, NCAN, LYPLAL1 and TM6SF2 genes ...
Angelico F, Angeloni A, Arca M, Bailetti D, Baratta F, Belardinilli F, Ceci F, D'Erasmo L, De Masi B, Del Ben M, Di Costanzo A, Giannini G, Girelli G, Montali A, Pastori D, Polimeni L, Sponziello M   +16 more
core   +1 more source

Genomewide association for a dominant pigmentation gene in sheep

Journal of Animal Breeding and Genetics, 2013
SummaryMost published genomewide association studies (GWAS) in sheep have investigated recessively inherited monogenic traits. The objective here was to assess the feasibility of performing GWAS for a dominant trait for which the genetic basis was already known.
Kijas, James, Serrano Noreña, Magdalena, McCulloch, R., Li, Y., Salces-Ortiz, Judit, Calvo, Jorge Hugo, Pérez-Guzmán, M. D.   +6 more
openaire   +5 more sources

Day-to-day dynamics of commensal Escherichia coli in Zimbabwean cows evidence temporal fluctuations within a host-specific population structure [PDF]

, 2017
To get insights into the temporal pattern of commensal Escherichia coli populations, we sampled the feces of four healthy cows from the same herd in the Hwange District of Zimbabwe daily over 25 days. The cows had not received antibiotic treatment during
Andremont, Antoine, Caron, Alexandre, Chatel, Jérémie, Clermont, Olivier, Couffignal, Camille, D'Humières, Camille, Denamur, Erick, Massot, Méril, Mentré, France, Plault, Nicolas   +9 more
core   +1 more source

Polysaccharide utilization loci and nutritional specialization in a dominant group of butyrate-producing human colonic Firmicutes

Microbial Genomics, 2016
Firmicutes and Bacteroidetes are the predominant bacterial phyla colonizing the healthy human large intestine. Whilst both ferment dietary fibre, genes responsible for this important activity have been analysed only in the Bacteroidetes, with very little
Paul O. Sheridan, Jennifer C. Martin, T. Lawley, H. Browne, H. Harris, A. Bernalier-Donadille, S. Duncan, P. O’Toole, Karen P. Scott, Harry J. Flint   +9 more
semanticscholar   +1 more source

The molecular genetic analysis of the expanding pachyonychia congenita case collection [PDF]

, 2014
BACKGROUND: Pachyonychia congenita (PC) is a rare autosomal dominant keratinizing disorder characterized by severe, painful, palmoplantar keratoderma and nail dystrophy, often accompanied by oral leucokeratosis, cysts and follicular keratosis.
Al-Asadi, E., Hansen, C. D., McLean, W. H. I., Milstone, L. M., O'Toole, E., Schwartz, M. E., Shepherd, A. A., Smith, F. J. D., Sprecher, E., Wilson, N. J.   +9 more
core   +2 more sources

Nucleolar dominance in triticales: control by unlinked genes.

Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology, 1997
Hybrid plants and animals often show suppression of activity of ribosomal genes (rDNA) originating from one of the parental or ancestral species. In the wheat x rye amphiploid triticale, containing 28 chromosomes of wheat origin and 14 from rye, rDNA of rye origin (on chromosome 1R) is not normally expressed, while the 1B- and 6B-origin rDNA from wheat
Neves, N., Silva, M., Heslop-Harrison, J.S., Viegas, W.   +3 more
openaire   +4 more sources