Results 21 to 30 of about 391,292 (303)

Dose-sensitivity, conserved noncoding sequences and duplicate gene retention through multiple tetraploidies in the grasses.

open access: yesFrontiers in Plant Science, 2011
Whole genome duplications, or tetraplodies, are an important source of increased gene content. Following whole genome duplication, duplicate copies of many genes are lost from the genome.
James C Schnable   +3 more
doaj   +1 more source

Myxococcus xanthus DK1622 Coordinates Expressions of the Duplicate groEL and Single groES Genes for Synergistic Functions of GroELs and GroES

open access: yesFrontiers in Microbiology, 2017
Chaperonin GroEL (Cpn60) requires cofactor GroES (Cpn10) for protein refolding in bacteria that possess single groEL and groES genes in a bicistronic groESL operon.
Yue-zhong Li   +6 more
doaj   +1 more source

Conversion between duplicated genes generated by polyploidization contributes to the divergence of poplar and willow

open access: yesBMC Plant Biology, 2022
Background Gene conversion has an important effect on duplicate genes produced by polyploidization. Poplar (Populus trichocarpa) and willow (Salix brachista) are leading models and excellent green plants in the Salicaceae.
Jianyu Wang   +14 more
doaj   +1 more source

The DAXX co-repressor is directly recruited to active regulatory elements genome-wide to regulate autophagy programs in a model of human prostate cancer. [PDF]

open access: yes, 2015
While carcinoma of the prostate is the second most common cause of cancer death in the US, current methods and markers used to predict prostate cancer (PCa) outcome are inadequate.
Benner, Christopher   +2 more
core   +2 more sources

The Genomic Basis of Evolutionary Innovation in Pseudomonas aeruginosa.

open access: yesPLoS Genetics, 2016
Novel traits play a key role in evolution, but their origins remain poorly understood. Here we address this problem by using experimental evolution to study bacterial innovation in real time.
Macarena Toll-Riera   +3 more
doaj   +1 more source

A likelihood ratio test for changes in homeolog expression bias

open access: yesBMC Bioinformatics, 2019
Background Gene duplications are a major source of raw material for evolution and a likely contributor to the diversity of life on earth. Duplicate genes (i.e., homeologs, in the case of a whole genome duplication) may retain their ancestral function ...
Ronald D. Smith   +3 more
doaj   +1 more source

Duplicated membrane estrogen receptors in the European sea bass (Dicentrarchus labrax): Phylogeny, expression and regulation throughout the reproductive cycle [PDF]

open access: yes, 2018
The numerous estrogen functions reported across vertebrates have been classically explained by their binding to specific transcription factors, the nuclear estrogen receptors (ERs).
Alvarado, M. Victoria   +5 more
core   +1 more source

UVPAR: fast detection of functional shifts in duplicate genes

open access: yesBMC Bioinformatics, 2006
Background The imprint of natural selection on gene sequences is often difficult to detect. A plethora of methods have been devised to detect genetic changes due to selective processes.
Lucas J Ignasi   +3 more
doaj   +1 more source

Identification and characterisation of enteroaggregative Escherichia coli subtypes associated with human disease [PDF]

open access: yes, 2020
Enteroaggregative E. coli (EAEC) are a major cause of diarrhoea worldwide. Due to their heterogeneity and carriage in healthy individuals, identification of diagnostic virulence markers for pathogenic strains has been difficult.
Brett, Bernard   +9 more
core   +1 more source

Expression and regulatory asymmetry of retained Arabidopsis thaliana transcription factor genes derived from whole genome duplication

open access: yesBMC Evolutionary Biology, 2019
Background Transcription factors (TFs) play a key role in regulating plant development and response to environmental stimuli. While most genes revert to single copy after whole genome duplication (WGD) event, transcription factors are retained at a ...
Nicholas L. Panchy   +4 more
doaj   +1 more source

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