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MEIS homeobox genes in neuroblastoma
Cancer Letters, 2005The common pediatric tumor neuroblastoma originates from primitive neural crest-derived precursor cells of the peripheral nervous system. Neuroblastoma especially affects very young children, and can already be present at birth. Its early onset and cellular origin predict the involvement of developmental control genes in neuroblastoma etiology.
Geerts, Dirk +4 more
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Homeobox HOXA10 Gene Analysis in Cryptorchidism
Journal of Pediatric Endocrinology and Metabolism, 2004In male mice, targeted disruption of the homeobox gene hoxa10 causes cryptorchidism and infertility. Genetic alterations in exon 1 of HOXA10 have been found in a high number of boys with cryptorchidism.To evaluate whether mutations of HOXA10 can be a common cause of cryptorchidism.Genomic DNA was extracted from 18 patients with cryptorchidism (age 7-44
BERTINI V +5 more
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Conserved pleiotropy of an ancient plant homeobox gene uncovered by cis-regulatory dissection
Cell, 2021Anat Hendelman +2 more
exaly
CDX-2 Homeobox Gene Expression
The American Journal of Surgical Pathology, 2003FRANCHI, ALESSANDRO +3 more
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Deregulated homeobox gene expression in cancer: cause or consequence?
Nature Reviews Cancer, 2002Cory T Abate-Shen
exaly
The genesis and evolution of homeobox gene clusters
Nature Reviews Genetics, 2005Jordi Garcia-Fernandez
exaly