Global Analysis of Intercellular Homeodomain Protein Transfer [PDF]
Cell Reports, 2019 Summary: The homeodomain is found in hundreds of transcription factors that play roles in fate determination via cell-autonomous regulation of gene expression.
Eun Jung Lee +12 more
doaj +6 more sources
Homeodomain Proteins Directly Regulate ATM Kinase Activity [PDF]
Cell Reports, 2018 Summary: Ataxia-telangiectasia mutated (ATM) is a serine/threonine kinase that coordinates the response to DNA double-strand breaks and oxidative stress.
Tanya E. Johnson +8 more
doaj +3 more sources
Homeodomain proteins: an update. [PDF]
Chromosoma, 2016 Here, we provide an update of our review on homeobox genes that we wrote together with Walter Gehring in 1994. Since then, comprehensive surveys of homeobox genes have become possible due to genome sequencing projects.
Bürglin TR, Affolter M.
europepmc +8 more sources
Homeodomain Proteins: Cooperating to be different [PDF]
Current Biology, 1995 The product of the Drosophila extradenticle gene interacts cooperatively with homeodomain proteins encoded by homeotic selector genes, and may account in part for their distinct regulatory ...
Wilson, David S., Desplan, Claude
core +4 more sources
Homeodomain proteins hierarchically specify neuronal diversity and synaptic connectivity [PDF]
eLifeHow our brain generates diverse neuron types that assemble into precise neural circuits remains unclear. Using Drosophila lamina neuron types (L1-L5), we show that the primary homeodomain transcription factor (HDTF) brain-specific homeobox (Bsh) is ...
Chundi Xu +4 more
doaj +2 more sources
Regulation of Silk Genes by Hox and Homeodomain Proteins in the Terminal Differentiated Silk Gland of the Silkworm Bombyx mori [PDF]
Journal of Developmental Biology, 2016 The silk gland of the silkworm Bombyx mori is a long tubular organ that is divided into several subparts along its anteroposterior (AP) axis. As a trait of terminal differentiation of the silk gland, several silk protein genes are expressed with unique ...
Shigeharu Takiya +2 more
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Evaluating the role of a novel homeodomain protein in periodontal regenerative therapy: An in-vitro study [PDF]
Journal of Oral Biology and Craniofacial ResearchIntroduction: The goal of periodontal treatment is to halt disease progression and restore the structure and function of damaged periodontal tissues.
Bhavya Shetty +5 more
doaj +2 more sources
The HOXC6 homeodomain-containing proteins [PDF]
The international journal of biochemistry & cell biology, 1998 peer reviewedThe HOXC6 homeodomain-containing proteins act as transcription factors in the genetic control of multiple genes involved in development and cell differentiation.
Gielen, jacques, Chariot, Alain
core +4 more sources
Intercellular Trafficking of Homeodomain Proteins
The Plant Pathology Journal, 2005 Homeotic proteins have pivotal roles during the development of both plant and animals. Many homeotic proteins exert control over cell fate in cells where their genes are not expressed, i.e., in a non-cell autonomous manner.
Moon, Jun-Yeon +10 more
core +3 more sources
Decoding the mechanisms of cooperative DNA binding by the Paired-like homeodomain family [PDF]
Nature CommunicationsThe 36 Paired-like homeodomain transcription factors in humans are required for the development of many cell types, tissues, and organs as missense variants in 24 Paired-like genes have been associated with numerous diseases and developmental disorders ...
Brittany Cain +3 more
doaj +2 more sources