Results 11 to 20 of about 41,966 (223)
Homeodomain Proteins: Cooperating to be different [PDF]
Current Biology, 1995 The product of the Drosophila extradenticle gene interacts cooperatively with homeodomain proteins encoded by homeotic selector genes, and may account in part for their distinct regulatory properties.
Wilson, David S., Desplan, Claude
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Karyopherins in nuclear transport of homeodomain proteins during development [PDF]
Biochimica Et Biophysica Acta - Molecular Cell Research, 2011 Homeodomain proteins are crucial transcription factors for cell differentiation, cell proliferation and organ development. Interestingly, their homeodomain signature structure is important for both their DNA-binding and their nucleocytoplasmic ...
Wenduo Ye, Wenbo Lin, Alan M Tartakoff
exaly +4 more sources
Intercellular Trafficking of Homeodomain Proteins [PDF]
The Plant Pathology Journal, 2005 Homeotic proteins have pivotal roles during the development of both plant and animals. Many homeotic proteins exert control over cell fate in cells where their genes are not expressed, i.e., in a non-cell autonomous manner. Cell-to-cell communication, which delivers critical information for position-dependent specification of cell fate, is an essential
Seon-Won Kim +10 more
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NK-like homeodomain proteins activate NOTCH3-signaling in leukemic T-cells [PDF]
BMC Cancer, 2009 Background Homeodomain proteins control fundamental cellular processes in development and in cancer if deregulated. Three members of the NK-like subfamily of homeobox genes (NKLs), TLX1, TLX3 and NKX2-5, are implicated in T-cell acute lymphoblastic ...
Drexler Hans G +10 more
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Drosophila Homeodomain-Interacting Protein Kinase (Hipk) Phosphorylates the Homeodomain Proteins Homeobrain, Empty Spiracles, and Muscle Segment Homeobox. [PDF]
Int J Mol Sci, 2019 The Drosophila homeodomain-interacting protein kinase (Hipk) is the fly representative of the well-conserved group of HIPKs in vertebrates. It was initially found through its characteristic interactions with homeodomain proteins.
Steinmetz EL +3 more
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Modular control of glutamatergic neuronal identity in C. elegans by distinct homeodomain proteins. [PDF]
Cell, 2013 SummaryThe choice of using one of many possible neurotransmitter systems is a critical step in defining the identity of an individual neuron type. We show here that the key defining feature of glutamatergic neurons, the vesicular glutamate transporter ...
Serrano-Saiz E +5 more
europepmc +2 more sources
Amino acid sequence conservation in homeodomain proteins. [PDF]
, 2022 Sequence logo plots of protein domains involve in the function of homeodomain proteins. Although the C-terminal domain was not related to a function, it was displayed due to its high conservation in protein sequences. Amino acids are colored according to
Vilde Bruhn Kinneberg (12328777) +7 more
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Scientific Reports, 2023 HMX3 is a homeodomain protein with essential roles in CNS and ear development. Homeodomains are DNA-binding domains and hence homeodomain-containing proteins are usually assumed to be transcription factors.
William Haws +6 more
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The roles of HD-ZIP proteins in plant abiotic stress tolerance
Frontiers in Plant Science, 2022 Homeodomain leucine zipper (HD-ZIP) proteins are plant-specific transcription factors that contain a homeodomain (HD) and a leucine zipper (LZ) domain.
Yuxia Li +7 more
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Homeodomain proteins directly regulate ATM kinase activity [PDF]
, 2020 The ataxia-telangiectasia mutated (ATM) kinase is a master regulator involved in the detection and repair of DNA double-strand breaks (DSBs). The Mre11/Rad50/Nbs1 (MRN) complex recruits and activates ATM at DSBs, causing a signaling cascade to initiate ...
Johnson, Tanya Ellen
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