Results 41 to 50 of about 65,874 (228)

Vsx2 controls eye organogenesis and retinal progenitor identity via homeodomain and non-homeodomain residues required for high affinity DNA binding. [PDF]

PLoS Genetics, 2012
The homeodomain and adjacent CVC domain in the visual system homeobox (VSX) proteins are conserved from nematodes to humans. Humans with missense mutations in these regions of VSX2 have microphthalmia, suggesting both regions are critical for function ...
Changjiang Zou, Edward M Levine
doaj   +1 more source

BMP2 commitment to the osteogenic lineage involves activation of Runx2 by DLX3 and a homeodomain transcriptional network

, 2006
Several homeodomain (HD) proteins are critical for skeletal patterning and respond directly to BMP2 as an early step in bone formation. RUNX2, the earliest transcription factor proven essential for commitment to osteoblastogenesis, is also expressed in ...
Aberg, Acampora, Afzal, Amjad Javed, Andre J. van Wijnen, Aronow, Bae, Balint, Banerjee, Banerjee, Beanan, Bendall, Bryan, Cheng, Choi, Depew, Depew, Drissi, Drissi, Ducy, Ferrari, Fujita, Gary S. Stein, Gaur, Ghoul-Mazgar, Harris, Hassan, Hoffmann, Ichida, Ishii, Jane B. Lian, Janet L. Stein, Kim, Komori, Lallemand, Lee, Lengner, Lengner, Lundberg, Maria I. Morasso, Matthew Mandeville, McKeown, Miyama, Mohammad Q. Hassan, Nakashima, Newberry, Otto, Owen, Park, Pratap, Provot, Rahul S. Tare, Robinson, Robledo, Roca, Rosen, Ryoo, Satokata, Satokata, Semba, Shirakabe, Smith, Stricker, Suk Hee Lee, Ten Dijke, Vaes, van Gurp, Xu, Yoshizawa, Zaidi, Zaidi, Zambotti   +71 more
core   +1 more source

A role for heterodimerization in nuclear localization of a homeodomain protein [PDF]

Proceedings of the National Academy of Sciences, 1998
TheAmating type genes of the mushroomCoprinus cinereusencode two families of dissimilar homeodomain proteins (HD1 and HD2). The proteins heterodimerize when mating cells fuse to generate a transcriptional regulator that promotes expression of genes required for early steps in sexual development. In previous work we showed that heterodimerization brings
A, Spit, R H, Hyland, E J, Mellor, L A, Casselton   +3 more
openaire   +2 more sources

Transcriptional Regulation: a Genomic Overview [PDF]

, 2002
The availability of the Arabidopsis thaliana genome sequence allows a comprehensive analysis of transcriptional regulation in plants using novel genomic approaches and methodologies. Such a genomic view of transcription first necessitates the compilation
Riechmann, José Luis
core   +2 more sources

Expression of a truncated ATHB17 protein in maize increases ear weight at silking. [PDF]

PLoS ONE, 2014
ATHB17 (AT2G01430) is an Arabidopsis gene encoding a member of the α-subclass of the homeodomain leucine zipper class II (HD-Zip II) family of transcription factors.
Elena A Rice, Abha Khandelwal, Robert A Creelman, Cara Griffith, Jeffrey E Ahrens, J Philip Taylor, Lesley R Murphy, Siva Manjunath, Rebecca L Thompson, Matthew J Lingard, Stephanie L Back, Huachun Larue, Bonnie R Brayton, Amanda J Burek, Shiv Tiwari, Luc Adam, James A Morrell, Rico A Caldo, Qing Huai, Jean-Louis K Kouadio, Rosemarie Kuehn, Anagha M Sant, William J Wingbermuehle, Rodrigo Sala, Matt Foster, Josh D Kinser, Radha Mohanty, Dongming Jiang, Todd E Ziegler, Mingya G Huang, Saritha V Kuriakose, Kyle Skottke, Peter P Repetti, T Lynne Reuber, Thomas G Ruff, Marie E Petracek, Paul J Loida   +36 more
doaj   +1 more source

The homeodomain transcription factor Phox2 in the stellate ganglion of the squid Loligo pealei

Biology Open, 2015
Homeodomain transcription factors regulate development of embryos and cellular physiology in adult systems. Paired-type homeodomain genes constitute a subclass that has been particularly implicated in establishment of neuronal identity in the mammalian ...
J. Peter H. Burbach, Anita J. C. G. M. Hellemons, Philip Grant, Harish C. Pant   +3 more
doaj   +1 more source

PHD finger proteins function in plant development and abiotic stress responses: an overview

Frontiers in Plant Science, 2023
The plant homeodomain (PHD) finger with a conserved Cys4-His-Cys3 motif is a common zinc-binding domain, which is widely present in all eukaryotic genomes.
Wenli Quan, Wenli Quan, Zhulong Chan, Piwei Wei, Yahui Mao, Dorothea Bartels, Xun Liu   +6 more
doaj   +1 more source

In planta localisation patterns of MADS domain proteins during floral development in Arabidopsis thaliana [PDF]

, 2009
Background: MADS domain transcription factors play important roles in various developmental processes in flowering plants. Members of this family play a prominent role in the transition to flowering and the specification of floral organ identity. Several
Angenent, G.C., Folter, S., de, Immink, G.H., Kaufmann, K., Shchennikova, A., Urbanus, S.L.   +5 more
core   +3 more sources

NaNog: A pluripotency homeobox (master) molecule. [PDF]

, 2015
One of the most intriguing aspects of cell biology is the state of pluripotency, where the cell is capable of self-renewal for as many times as deemed necessary , then at a specified time can differentiate into any type of cell. This fundamental process
Aguib, YE, Allouba, MH, ElGuindy, AM, Krishnamoorthy, N, Yacoub, MH   +4 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source