Results 211 to 220 of about 232,012 (258)
Some of the next articles are maybe not open access.
Immunoglobulin Gene Diversification
Annual Review of Genetics, 2005Three processes alter genomic sequence and structure at the immunoglobulin genes of B lymphocytes: gene conversion, somatic hypermutation, and class switch recombination. Though the molecular signatures of these processes differ, they occur by a shared pathway which is induced by targeted DNA deamination by a B cell–specific factor, activation induced
openaire +2 more sources
Immunoglobulin Gene Diversification by Gene Conversion
1993Publisher Summary This chapter discusses recent advances in the study of gene conversion, primarily in the chicken, and on current models for the molecular mechanism of this form of somatic gene conversion. Most of the higher vertebrates, including teleost fish, the amphibian Xenopus, the reptile Caiman, and most of the mammalian species studied ...
W T, McCormack +2 more
openaire +2 more sources
Transgenic Mice With Immunoglobulin Genes
Annual Review of Immunology, 1987Immunoglobulin (Ig) genes encode antibody molecules expressed exclu sively in the B-Iymphocyte lineage. The most immature identifiable cells of the B-cell lineage, pre-B cells, give rise to B cells that differentiate terminally into antibody secreting plasma cells.
openaire +2 more sources
The Structure of Immunoglobulins and Immunoglobulin Genes
1975Immunoglobulins are members of that family of homologous proteins which includes the humoral antibodies. An antibody is a protein which appears in increased amounts in the body fluids of most vertebrates following the introduction of a foreign substance (antigen) into the body, and which is able to bind specifically to that antigen.
openaire +1 more source
Dynamics of Immunoglobulin Genes
Immunological Reviews, 1977S, Tonegawa +4 more
openaire +2 more sources
Production and Function of Immunoglobulin A
Annual Review of Immunology, 2021Timothy Hand, Andrea Reboldi
exaly