A Scalable Framework for Comprehensive Typing of Polymorphic Immune Genes from Long‐Read Data
SpecImmune introduces a unified computational framework optimized for long‐read sequencing to resolve over 400 highly polymorphic immune genes. This scalable approach achieves high‐resolution typing, enabling the discovery of cross‐family co‐evolutionary networks and population‐specific diversity.
Shuai Wang +5 more
wiley +1 more source
Comparison of Diagnostic Performance of Commercially Available Serological and Molecular Tests for Detection of <i>Orientia tsutsugamushi</i> in South Korea: A Single-Center Prospective Study. [PDF]
Kim S +9 more
europepmc +1 more source
In wild‐type cells, FIPV infection recruits CLTC to nsp3, facilitates DMV biogenesis and block autophagic flux to promote viral replication. CLTC knockout impairs autophagosome nucleation by reducing Beclin1–ATG14 complex expression. This disrupts the formation of autophagic precursor membranes, thereby preventing their hijacking by nsp3 for DMV ...
Juan Xu +9 more
wiley +1 more source
Leukocyte immunoglobulin-like receptor B2 regulates atherosclerosis progression by modulating macrophage extracellular trap formation in foam macrophages through the PI3K-AKT signaling pathway. [PDF]
Jiao Y +5 more
europepmc +1 more source
Transcriptome-Proteome Analysis of Human Naive and Memory B Cell Subsets Reveals Isotype and Subclass-Specific Phenotypes. [PDF]
Koers J +6 more
europepmc +1 more source
Case Report: Clonal evolution of diffuse large B-cell lymphoma to plasmablastic lymphoma: diagnostic challenges in a case of gastric lesion with EBV-negative PBL. [PDF]
Xu J +6 more
europepmc +1 more source
Novel variants related to extreme elevation of serum IgE in Vietnamese patients with primary immunodeficiency: Case report. [PDF]
Huong LTM +10 more
europepmc +1 more source
Oligoclonal B cell expansion and passenger fusion genes predict response to Nivolumab in recurrent ovarian cancer: phase II Kyoto trial. [PDF]
Murakami R +11 more
europepmc +1 more source

