Results 81 to 90 of about 224,267 (330)

Major Histocompatibility Complex (MHC) Genes and Disease Resistance in Fish

open access: yesCells, 2019
Fascinating about classical major histocompatibility complex (MHC) molecules is their polymorphism. The present study is a review and discussion of the fish MHC situation. The basic pattern of MHC variation in fish is similar to mammals, with MHC class I
Takuya Yamaguchi, Johannes M. Dijkstra
doaj   +1 more source

Highly efficient peptide binding and T cell activation by MHC class II molecules of CIITA-transfected cells [PDF]

open access: yes, 2017
Expression of MHC class II, DM and li genes is controlled by the transactivator CIITA, a mediator of the activation of these genes by IFN-γ. Surprisingly, MHC class II molecules expressed on CIITA transfectants behave very differently from those ...
Mach, Bernard   +2 more
core  

Cryptic female choice favours sperm from major histocompatibility complex-dissimilar males [PDF]

open access: yes, 2013
Cryptic female choice may enable polyandrous females to avoid inbreeding or bias offspring variability at key loci after mating. However, the role of these genetic benefits in cryptic female choice remains poorly understood. Female red junglefowl, Gallus
Alcaide M   +8 more
core   +1 more source

Host‐Directed Biomaterials for Combatting Bloodstream Infections: From Macrocyclic Peptides to Immune‐Activating Cell Backpacks

open access: yesAdvanced Functional Materials, EarlyView.
Bloodstream infections (BSI) are one of the leading causes of mortality and morbidity in both civilian and military populations. This paper summarizes recent progress in novel treatment strategies to manage BSI arising from both bacterial and fungal pathogens using molecules, particles, and materials to elicit host‐directed immunity.
Thomas Thomou   +11 more
wiley   +1 more source

Correlation in chicken between the marker LEI0258 alleles and Major Histocompatibility Complex sequences

open access: yesBMC Proceedings, 2011
Background The LEI0258 marker is located within the B region of the chicken Major Histocompatibility Complex (MHC), and is surprisingly well associated with serology.
Chazara Olympe   +4 more
doaj   +1 more source

The porcine Major Histocompatibility Complex and related paralogous regions: a review

open access: yesGenetics Selection Evolution, 2000
The physical alignment of the entire region of the pig major histocompatibility complex (MHC) has been almost completed. In swine, the MHC is called the SLA (swine leukocyte antigen) and most of its class I region has been sequenced.
Vaiman Marcel   +3 more
doaj   +1 more source

Major histocompatibility complex class I involvement in the rejection of allogeneic erythrocytes in rainbow trout (Oncorhynchus mykiss) [PDF]

open access: yes, 2003
Major histocompatibility complex genes are thought to be involved in allogeneic graft rejection but not many reports are available on their functional analysis in fish.
Sarder, M.R.I.
core  

The multigenic structure of the MHC locus contributes to positive selection efficiency: A role for MHC class II gene-genespecific [PDF]

open access: yes, 2005
This deposit is in restrictedAccess (it can't be in open access to the public), and can only be accessed by two ways: either by requesting a legal copy from the author (the email contact present in this deposit) or by visiting the following link: https:/
Couceiro, Sofia   +2 more
core   +1 more source

Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System

open access: yesAdvanced Functional Materials, EarlyView.
A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim   +4 more
wiley   +1 more source

Antigen-presenting genes and genomic copy number variations in the Tasmanian devil MHC

open access: yes, 2015
BACKGROUND The Tasmanian devil (Sarcophilus harrisii) is currently under threat of extinction due to an unusual fatal contagious cancer called Devil Facial Tumour Disease (DFTD).
Amemiya, Chris T   +8 more
core   +1 more source

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