Results 1 to 10 of about 243,525 (310)

CIITA (MHC class II transactivator) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on CIITA (MHC class II transactivator), with data on DNA, on the protein encoded, and where the gene is implicated.
openaire   +1 more source

Expressions of HLA Class II Genes in Cutaneous Melanoma Were Associated with Clinical Outcome: Bioinformatics Approaches and Systematic Analysis of Public Microarray and RNA-Seq Datasets

Diagnostics, 2019
Major histocompatibility complex (MHC) class II molecules, encoded by human leukocyte antigen (HLA) class II genes, play important roles in antigen presentation and initiation of immune responses.
Yang-Yi Chen, Wei-An Chang, En-Shyh Lin, Yi-Jen Chen, Po-Lin Kuo   +4 more
doaj   +1 more source

Mouse CD4 binds MHC class II with extremely low affinity [PDF]

, 2017
Interaction of CD4 with MHC class II molecules plays a crucial role during thymic development and activation of singie-positive CD4 T lymphocytes. The quantitation of this interaction is, therefore, important for understanding the role of CD4 during ...
Karjalainen, Klaus, Weber, Susanna
core  

Model for the Interaction of T-cell Receptors with Peptide/MHC Complexes [PDF]

, 1989
The immune response against a viral infection is mediated by two different types of cells known as B and T lymphocytes. The receptor on the B cell is the well-characterized antibody molecule, which exists in a membrane-bound form and in a secreted form ...
Bjorkman, P. J., Davis, M. M.
core   +1 more source

Major Histocompatibility Complex Class I Matching is Necessary but not Sufficient for Tolerance Induction to Vascularized Composite Allografts After Donor Hematopoietic Cell Transplantation

Transplantation Direct
Background. We previously reported a porcine model of vascularized composite allograft (VCA) transplantation with concurrent hematopoietic cell transplantation (HCT).
Elin Manell, DVM, PhD, M. Esad Gunes, MD, Sarah Merl, MBBS, Satyajit Patwardhan, MBBS, Ishit Chauhan, MBBS, Julie Hong, MD, Bryan Chen, BS, BA, Philip Jordache, BS, MS, Ahmed Almesalmy, BS, Dilrukshi Ekanayake-Alper, DVM, PhD, Dominik Hajosi, DVM, Sameera Husain, MD, Cheng-Shie Wuu, PhD, Matthew Wright, MD, Jarrod Bogue, MD, Christine Rohde, MD, Kumaran Shanmugarajah, MD, PhD, Curtis L Cetrulo, Jr, MD, David H. Sachs, MD, Joshua Weiner, MD   +19 more
doaj   +1 more source

Macroautophagy Proteins Control MHC Class I Levels on Dendritic Cells and Shape Anti-viral CD8+ T Cell Responses

Cell Reports, 2016
The macroautophagy machinery has been implicated in MHC class II restricted antigen presentation. Here, we report that this machinery assists in the internalization of MHC class I molecules.
Monica Loi, Anne Müller, Karin Steinbach, Jennifer Niven, Rosa Barreira da Silva, Petra Paul, Laure-Anne Ligeon, Assunta Caruso, Randy A. Albrecht, Andrea C. Becker, Nicolas Annaheim, Heike Nowag, Jörn Dengjel, Adolfo García-Sastre, Doron Merkler, Christian Münz, Monique Gannagé   +16 more
doaj   +1 more source

MHC presentation via autophagy and how viruses escape from it [PDF]

, 2018
T cells detect infected and transformed cells via antigen presentation by major histocompatibility complex (MHC) molecules on the cell surface. For T cell stimulation, these MHC molecules present fragments of proteins that are expressed or taken up by ...
Gannage, Monique, Münz, Christian
core  

A block in degradation of MHC class II-associated invariant chain correlates with a reduction in transport from endosome carrier vesicles to the prelysosome compartment [PDF]

, 1992
Invariant chain (Ii) associated with MHC class II molecule is processed proteolytically via several distinct intermediates during its intracellular transport through endosomal compartments.
Dobberstein, Bernhard, Griffiths, Gareth, Zachgo, Sabine   +2 more
core   +1 more source

Deteksi Protein Bovine Major Histocompatibility Complex Klas I dan Klas II pada Sapi Madura

Jurnal Veteriner, 2008
A study to detect the presence of bovine major histocompatibility complex (Bo-MHC) in maduracattle has been carried out. Lymphocyte samples were collected from 25 cattle.
Ni Ketut Suwiti, Fedik Abdul Rantam, I Nengah Kerta Besung   +2 more
doaj  

Gut mesenchymal stromal cells in immunity [PDF]

, 2017
Mesenchymal stromal cells (MSCs), first found in bone marrow (BM), are the structural architects of all organs, participating in most biological functions.
Biancone, Livia, Buccione, Carla, Marotta, Giulia, Mattia, Gianfranco, Messina, Valeria, Puglisi, Rossella, Sacchetti, Benedetto, Signore, Michele, Valtieri, Mauro, Ziccheddu, Giovanna   +9 more
core   +4 more sources