Results 31 to 40 of about 243,525 (310)

MHC Class II epitope predictive algorithms [PDF]

open access: yesImmunology, 2010
SummaryMajor histocompatibility complex class II (MHC‐II) molecules sample peptides from the extracellular space, allowing the immune system to detect the presence of foreign microbes from this compartment. To be able to predict the immune response to given pathogens, a number of methods have been developed to predict peptide–MHC binding.
Nielsen, Morten   +3 more
openaire   +3 more sources

Xenografts of MHC-Deficient Mouse Embryonic Mesencephalon Improve Behavioral Recovery in Hemiparkinsonian Rats

open access: yesCell Transplantation, 2002
The limited availability of human embryonic tissue for dopamine cell transplants in Parkinson's patients has led to an increased interest in using xenogeneic donor tissue.
Lone M. Veng   +7 more
doaj   +1 more source

Atlantic cod (Gadus morhua) MHC I localizes to endolysosomal compartments independently of cytosolic sorting signals

open access: yesFrontiers in Cell and Developmental Biology, 2023
Major histocompatibility complex (MHC) class I and II are crucial for the adaptive immune system because they are involved in peptide presentation to T cells.
Synne Arstad Bjørnestad   +5 more
doaj   +1 more source

Diminished Intracellular Invariant Chain Expression Following Vaccinia Virus Infection [PDF]

open access: yes, 2009
Vaccinia virus (VV) has been used as a vaccine to eradicate smallpox and as a vaccine for HIV and tumors. However, the immunoevasive properties of VV, have raised safety concerns.
Blum, Janice S.   +2 more
core   +1 more source

Expression of MHC Class I and II in Growing Ovarian Follicles of Young and Old Laying Hens, Gallus domesticus

open access: yesThe Journal of Poultry Science, 2005
The aim of this study was to determine whether the expressions of MHC class I and II in the ovarian follicles change with follicular growth and aging of birds. Theca layer of white follicles (WF), the largest and the third largest preovulatory follicles
Kalpana Subedi, Yukinori Yoshimura
doaj   +1 more source

Lack of association between alopecia areata and HLA class I and II in a southeastern Brazilian population [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2016
: Background: Alopecia areata (AA) is a common disorder of unknown etiology that affects approximately 0.7% to 3.8% of patients among the general population. Currently, genetic and autoimmune factors are emphasized as etiopathogenic.
Ângela Marques Barbosa   +7 more
doaj   +1 more source

MHC and Evolution in Teleosts

open access: yesBiology, 2016
Major histocompatibility complex (MHC) molecules are key players in initiating immune responses towards invading pathogens. Both MHC class I and class II genes are present in teleosts, and, using phylogenetic clustering, sequences from both classes have ...
Unni Grimholt
doaj   +1 more source

MHC class II expression and potential antigen-presenting cells in the retina during experimental autoimmune uveitis

open access: yesJournal of Neuroinflammation, 2017
Background Controversy exists regarding which cell types are responsible for autoantigen presentation in the retina during experimental autoimmune uveitis (EAU) development.
Deborah A. Lipski   +6 more
doaj   +1 more source

Costimulatory molecule-deficient dendritic cell progenitors (MHC class II+, CD80(dim), CD86-) prolong cardiac allograft survival in nonimmunosuppressed recipients [PDF]

open access: yes, 1996
We have shown previously that granulocyte-macrophage colony-stimulating factor-stimulated mouse bone marrow-derived MHC class II+ dendritic cell (DC) progenitors that are deficient in cell surface expression of the costimulatory molecules B7-1 (CD8O) and
Angus W. Thomson   +48 more
core   +1 more source

Mice lacking the MHC class II transactivator (CIITA) show tissue-specific impairment of MHC class II expression [PDF]

open access: yes, 1996
CIITA activates the expression of multiple genes involved in antigen presentation and it is believed to be required for both constitutive and IFN\xce\xb3-inducible expression of these genes.
Chang, C.-H. (Cheong-Hee)   +4 more
core   +1 more source

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