Results 71 to 80 of about 23,942 (228)

Infant frontal alpha asymmetry predicts social attention and transdiagnostic risk for emotional reactivity

JCPP Advances, EarlyView.
Abstract Background Differences in Frontal Alpha Asymmetry (FAA), derived from the electroencephalogram (EEG), have been associated with approach‐withdrawal behavior, although inconsistently. The current study examined how early patterns of FAA during the first 2 years of life relate to various socioemotional characteristics (at 2 years) and ultimately
Viviane Valdes, Niccola Lutri, Haerin Chung, Charles A. Nelson   +3 more
wiley   +1 more source

Integrated analysis of miRNA landscape and cellular networking pathways in stage-specific prostate cancer.

PLoS ONE, 2019
Dysregulation of miRNAs has been demonstrated in several human malignancies including prostate cancer. Due to tissue limitation and variable disease progression, stage-specific miRNAs changes in prostate cancer is unknown. Using chip-based microarray, we
Shiv Verma, Mitali Pandey, Girish C Shukla, Vaibhav Singh, Sanjay Gupta   +4 more
doaj   +1 more source

NF1 microdeletion syndrome: case report of two new patients

Italian Journal of Pediatrics, 2019
Background 17q11.2 microdeletions, which include the neurofibromatosis type 1 (NF1) gene region, are responsible for the NF1 microdeletion syndrome, observed in 4.2% of all NF1 patients.
Gregorio Serra, Vincenzo Antona, Giovanni Corsello, Federico Zara, Ettore Piro, Raffaele Falsaperla   +5 more
doaj   +1 more source

A proteasome-resistant fragment of NIK mediates oncogenic NF-κB signaling in schwannomas [PDF]

, 2019
Schwannomas are common, highly morbid and medically untreatable tumors that can arise in patients with germ line as well as somatic mutations in neurofibromatosis type 2 (NF2).
Angus, Steven P., Bessler, Waylan, Chen, Shi, Clapp, D. Wade, Edwards, Donna, Gehlhausen, Jeffrey R., Hawley, Eric, He, Yongzheng, Jiang, Li, Johnson, Gary L., Lajiness, Jacquelyn D., Li, Xiaohong, Nalepa, Grzegorz, Park, Su-Jung, Rhodes, Steven D., Sandusky, George, Smith, Abbi, Staser, Karl, Stemmer-Rachamimov, Anat, Stuhlmiller, Timothy J., Wahle, Benjamin Mark, Yang, Xianlin, Yates, Charles W., Yuan, Jin   +23 more
core   +1 more source

Yield of Whole Genome Sequencing for Pathogenic Single Nucleotide Variants in Congenital Heart Disease: A Systematic Review and Meta‐Analysis

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective This systematic review and meta‐analysis aimed to assess the diagnostic yield of pathogenic or likely pathogenic (P/LP) single nucleotide variants (SNVs) using whole genome sequencing (WGS) in congenital heart disease (CHD). Methods A systematic search of three databases (2000–2024) was conducted, and two reviewers independently ...
Hiba J. Mustafa, Parisa Najjariasl, Faezeh Aghajani, Enaja V. Sambatur, Andrew Rodenbarger, Stephanie Guseh, Amy E. Roberts, Alireza A. Shamshirsaz   +7 more
wiley   +1 more source

Pancancer landscape analysis of the thymosin family identified TMSB10 as a potential prognostic biomarker and immunotherapy target in glioma

Cancer Cell International, 2022
Background Thymosin family genes (TMSs), biologically important peptides with diverse intracellular and extracellular functions, have been shown to promote the progression of multiple cancers.
Ye Xiong, Yanhua Qi, Ziwen Pan, Shaobo Wang, Boyan Li, Bowen Feng, Hao Xue, Rongrong Zhao, Gang Li   +8 more
doaj   +1 more source

Neurofibromatosis type 1: Fundamental insights into cell signalling and cancer [PDF]

, 2016
Neurofibromatosis type 1 (NF1) is an autosomal dominant tumour predisposition syndrome that is caused through loss of function mutations of a tumour suppressor gene called Neurofibromin 1.
Rad, Ellie, Tee, Andrew
core   +2 more sources

Pediatric spinal ependymomas: Long‐term surgical outcomes in a cohort of 61 cases

Pediatric Investigation, EarlyView.
Spinal ependymomas are rare in children, with limited long‐term outcome data. In this retrospective study of 61 pediatric patients undergoing surgical resection, gross total resection was achieved in 62.3% and was associated with favorable functional improvement. Recurrence was observed in 31.1% of cases.
Liang Zhang, Xingyu Liu, Bo Han, Wenqing Jia   +3 more
wiley   +1 more source

Differences in MWCNT- and SWCNT-induced DNA methylation alterations in association with the nuclear deposition

Particle and Fibre Toxicology, 2018
Background Subtle DNA methylation alterations mediated by carbon nanotubes (CNTs) exposure might contribute to pathogenesis and disease susceptibility.
Deniz Öner, Manosij Ghosh, Hannelore Bové, Matthieu Moisse, Bram Boeckx, Radu C. Duca, Katrien Poels, Katrien Luyts, Eveline Putzeys, Kirsten Van Landuydt, Jeroen AJ Vanoirbeek, Marcel Ameloot, Diether Lambrechts, Lode Godderis, Peter HM Hoet   +14 more
doaj   +1 more source

Ewing sarcoma in a child with neurofibromatosis type 1. [PDF]

, 2019
We report here on a case of Ewing sarcoma (ES) occurring in a child with neurofibromatosis type 1. The sarcoma had an EWSR1-ERG translocation as well as loss of the remaining wild-type allele of NF1. Loss of the NF1 wild-type allele in the tumor suggests
Bastian, Boris C, Fernandez, Karen S, Hardee, Steven, Horvai, Andrew, Shah, Avanthi Tayi, Sweet-Cordero, E Alejandro, Turski, Michelle L   +6 more
core