Results 151 to 160 of about 373,131 (211)

Editorial: Advances in systems neurogenetics. [PDF]

Front Neurosci
Carney P, Zhang B.
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CRISPR knockout screens reveal JUN as the master mediator of resistance to MAPK inhibition in KRAS-mutant pancreatic cancer. [PDF]

J Exp Clin Cancer Res
Mulero-Sánchez A, Bosma A, Visuvasam B, Pouliopoulou N, van de Ven M, Proost N, Boeije M, Lieftink C, Beijersbergen R, Bernards R, Mainardi S.   +10 more
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Oncogenic RAS activity is linked to immune priming and adenosine-driven immune evasion in lung adenocarcinoma

de Carné Trécesson S, East P, Pillsbury CE, dos Santos MS, Cha H, Colliver E, Gilmore T, Rana S, Moore C, Lighterness S, Caswell D, Boumelha J, Tomaschko M, Baer R, Eyles J, Teixeira B, Saeed M, Litchfield K, Molina-Arcas M, Lee S, MacRae JI, Hobson P, Swanton C, Downward J.   +23 more
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Extensive sequence homology of the goldfish ras gene to mammalian ras genes

Differentiation, 1986
We cloned ras-related sequences from goldfish genomic libraries constructed as recombinants using the lambda phage. Restriction enzyme mapping of the clones obtained revealed three kinds of ras-related sequences among approximately 350,000 genomic clones. One of these clones was partially sequenced. Comparison with the nucleotide sequences of mammalian
N, Nemoto, K, Kodama, A, Tazawa, P, Masahito, T, Ishikawa   +4 more
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H-RAS, K-RAS, and N-RAS Gene Activation in Human Bladder Cancers

Cancer Genetics and Cytogenetics, 2000
Bladder cancer is one of the leading causes of cancer death in most developed countries. In this work, 19 bladder cancer specimens, along with their infiltrations of the urinary bladder wall from the same patients, were examined for the presence of H-RAS, K-RAS, and N-RAS activation using a polymerase chain reaction-restriction fragment length ...
B, Przybojewska, A, Jagiello, P, Jalmuzna   +2 more
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Conversion of ras Genes to Cancer Genes

1987
The cellular precursor of Harvey and Balb sarcoma virus, termed proto-ras, from certain tumors registers most frequently as an apparent cancer gene in the gene transfer assay with NIH 3T3 cells [1–4]. The viral ras gene is a dominant transforming gene that elicits all features of oncogenic transformation in a single step upon transfer into established ...
K, Cichutek, P H, Duesberg
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A novel ras-related gene family

Cell, 1985
We have identified a new family of ras genes, the rho genes, which share several properties with the more classical ras gene family consisting of N-, K-, and H-ras. The rho genes, first isolated from a cDNA library from the abdominal ganglia of Aplysia, encode proteins that share 35% amino acid homology with H-ras. Evolutionarily conserved counterparts
P, Madaule, R, Axel
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Targeting Ras Genes in Kidney Disease

Nephron Experimental Nephrology, 2004
Certain changes in cellular function are characteristic of renal disease. Foremost among these is the excessive proliferation of cells, but other phenotypic changes include dysregulated apoptosis, migration, adhesion, contraction, secretion, and receptor expression. Recent advances in cell biology have revealed an extensive role for the small monomeric
Hendry, B M, Sharpe, C C
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Dictyostelium ras genes

1995
Abstract Five ras genes (rasB, rasC, rasD, rasG and rasS) and one rap gene (rap1) have been isolated and characterized in the cellular slime mold Dictyostelium discoideum (Daniel etal. 1993,1994; Reymond etal. 1984; Robbins eta/. 1989,1990).
Juliet Daniel, Gerald Weeks, George B Spiegelman   +2 more
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Ras-like genes and gene families in the mouse

Mammalian Genome, 1991
Four human RAS-like cDNAs and a mouse genomic DNA fragment were used to define novel mouse Ras-like genes and gene families. Inheritance of DNA restriction fragment length variants associated with these genes in recombinant inbred and backcross mice allowed definition of 12 genetic loci, nine of which were mapped, to chromosomes (Chr) 2, 4, 7, 8, 9 ...
G, Drivas, R, Massey, H Y, Chang, M G, Rush, P, D'Eustachio   +4 more
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