Results 81 to 90 of about 373,131 (211)

Renin-angiotensin-aldosterone system in ISIAH rats with stressinduced arterial hypertension

Вавиловский журнал генетики и селекции, 2017
Because the renin-angiotensin system (RAS) has a wide range of opportunities in the regulation of fluid and electrolyte balance and arterial pressure, it is currently hypothesized that alterations in systemic circulating or local tissue RAS are some of ...
A. D. Dubinina, E. V. Antonov, L. A. Fedoseeva, E. N. Pivovarova, A. L. Markel, L. N. Ivanova   +5 more
doaj   +1 more source

Characterization of mutations and loss of heterozygosity of p53 and K-\u3ci\u3eras\u3c/i\u3e2 in pancreatic cancer cell lines by immobilized polymerase chain reaction [PDF]

, 2003
Background The identification of known mutations in a cell population is important for clinical applications and basic cancer research. In this work an immobilized form of the polymerase chain reaction, referred to as polony technology, was used to ...
Butz, James, Edwards, Jeremy, Wickstrom, Eric   +2 more
core   +1 more source

[K-ras gene mutation in gallbladder carcinoma].

Revista medica de Chile, 2004
8
Roa, JC, Roa, I, de Aretxabala, X, Melo, A, Faria, G, Tapia, O   +5 more
openaire   +4 more sources

Biological aspects and tumorigenic activity of the Ras proto-oncogenic family
Aspectos biológicos e atividade tumorigênica da família proto-oncogênica Ras

Semina: Ciências Biológicas e da Saúde, 2010
Proto-oncogenes play an important role in the regulation of the cellular cycle, being critical to the tumorigenesis. In this category we can find the RAS family.
Juliano André Boquett, Reginaldo Justino Ferreira   +1 more
doaj  

Ras-AKT signaling represses the phosphorylation of histone H1.5 at threonine 10 via GSK3 to promote the progression of glioma

Artificial Cells, Nanomedicine, and Biotechnology, 2019
Background Histone H1.5 has been considered as a novel cancer marker as its expression is associated with various human cancers. The objective of this study was to explore the effects of H1.5 phosphorylation in Ras-driven growth and migration of glioma ...
Ben Sang, Jianjing Sun, Dongxu Yang, Zhen Xu, Yuzhen Wei   +4 more
doaj   +1 more source

RAB family gene expression in breast cancer cells under influence of paclitaxel [PDF]

, 2011
The aim of this study was to investigate the role of paclitaxel on RAB family of genes in primary breast cancer cell lines. The cancer breast cells obtained from 40 women during mastectomy were used to address this issue. The group included patients with
Andrzej Wilkolaski, Jolanta Rzymowska, Piotr Maj, Tadeusz Malewski   +3 more
core   +1 more source

Breast tumors with elevated expression of 1q candidate genes confer poor clinical outcome and sensitivity to Ras/PI3K inhibition.

PLoS ONE, 2013
Genomic aberrations are common in cancers and the long arm of chromosome 1 is known for its frequent amplifications in breast cancer. However, the key candidate genes of 1q, and their contribution in breast cancer pathogenesis remain unexplored.
Muthulakshmi Muthuswami, Vignesh Ramesh, Saikat Banerjee, Soundara Viveka Thangaraj, Jayaprakash Periasamy, Divya Bhaskar Rao, Georgina D Barnabas, Swetha Raghavan, Kumaresan Ganesan   +8 more
doaj   +1 more source

Patterning of the C. elegans 1° vulval lineage by RAS and Wnt pathways [PDF]

, 2000
In C. elegans, the descendants of the 1° vulval precursor cell (VPC) establish a fixed spatial pattern of two different cell fates: E-F-F-E. The two inner granddaughters attach to the somatic gonadal anchor cell (AC) and generate four vulF cells, while ...
Sternberg, Paul W., Wang, Minqin
core  

RAS diseases in children

Haematologica, 2014
RAS genes encode a family of 21 kDa proteins that are an essential hub for a number of survival, proliferation, differentiation and senescence pathways. Signaling of the RAS-GTPases through the RAF-MEK-ERK pathway, the first identified mitogen-associated
Charlotte M. Niemeyer
doaj   +1 more source

Elucidating Ras protein as a dual therapeutic target for inflammation and cancer: a review

Discover Oncology
Cancer, one of the most dreadful diseases of the twenty-first century develops as a result of unregulated inflammatory responses and mutations of genes.
Parmar Keshri Nandan, Jayanthi Sivaraman
doaj   +1 more source