Results 31 to 40 of about 5,250,240 (290)

Assessment of a 44 gene classifier for the evaluation of chronic fatigue syndrome from peripheral blood mononuclear cell gene expression. [PDF]

PLoS ONE, 2011
Chronic fatigue syndrome (CFS) is a clinically defined illness estimated to affect millions of people worldwide causing significant morbidity and an annual cost of billions of dollars.
Daniel Frampton, Jonathan Kerr, Tim J Harrison, Paul Kellam   +3 more
doaj   +1 more source

Efficient generation of mNeonGreen Plasmodium falciparum reporter lines enables quantitative fitness analysis

Frontiers in Cellular and Infection Microbiology, 2022
CRISPR editing has enabled the rapid creation of fluorescent Plasmodium transgenic lines, facilitating a deeper understanding of parasite biology. The impact of genetic perturbations such as gene disruption or the introduction of drug resistance alleles ...
Johanna Hoshizaki, Hannah Jagoe, Marcus C. S. Lee   +2 more
doaj   +1 more source

Imaging Molecular Pathways: Reporter Genes [PDF]

Radiation Research, 2012
Molecular imaging is a rapidly advancing field that allows cancer biologists to look deeper into the complex inner workings of tumor cells, or whole tumors, in a non-invasive manner. In this review, we will summarize some recent advances that enable investigators to study various important biological processes in tumors in vivo.
John, Brogan, Fang, Li, Wenrong, Li, Zhimin, He, Qian, Huang, Chuan-Yuan, Li   +5 more
openaire   +2 more sources

Magnetic Resonance Reporter Gene Imaging [PDF]

Theranostics, 2012
Molecular imaging has undergone an explosive advancement in recent years, due to the tremendous research efforts made to understand and visualize biological processes. Molecular imaging by definition assesses cellular and molecular processes in living subjects, with the targets of following metabolic, genomic, and proteomic events.
Lee, Sheen-Woo, Lee, Sang-Hoon, Biswal, Sandip   +2 more
openaire   +2 more sources

Infection by Bacterial Pathogens Expressing Type III Secretion Decreases Luciferase Activity: Ramifications for Reporter Gene Studies

BioTechniques, 2000
Pathogenic microbes influence gene regulation in eukaryotic hosts. Reporter gene studies can define the roles of promoter regulatory sequences. The effect of pathogenic bacteria on reporter genes has not been examined.
Suzana D. Savkovic, Athanasia Koutsouris, Gary Wu, Gail Hecht   +3 more
doaj   +1 more source

Preparation and application of chikungunya pseudovirus containing double reporter genes

Scientific Reports, 2022
Chikungunya virus (CHIKV), a highly infectious and rapidly spread viral pathogen, is classified as a pathogenic agent at the biosafety level 3. Operation of live authentic CHIKV needs a specific laboratory with the P3 or above containment, which greatly ...
Chunyan Su, Kaiyun Ding, Jingwen Xu, Jianchao Wu, Jiansheng Liu, Jiayuan Shen, Hongning Zhou, Hongqi Liu   +7 more
doaj   +1 more source

Sickle Cell Disease Is an Inherent Risk for Asthma in a Sibling Comparison Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Sickle cell disease (SCD) and asthma share a complex relationship. Although estimates vary, asthma prevalence in children with SCD is believed to be comparable to or higher than the general population. Determining whether SCD confers an increased risk for asthma remains challenging due to overlapping symptoms and the ...
Suhei C. Zuleta De Bernardis, Okeleji Olayinka, Mariam Z. Quraishi, Lakshmi V. Srivaths, Deborah L. Brown, Neethu M. Menon, Ricardo A. Mosquera, Ashwin P. Patel, James M. Stark, Aravind Yadav   +9 more
wiley   +1 more source

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus, Floortje Strobbe, Annemarie A. Verrijn Stuart, Hanneke M. van Santen, Gerlof D. Valk, Sasja A. Schepers, Rachel S. van Leeuwaarde   +6 more
wiley   +1 more source

A cell culture adapted HCV JFH1 variant that increases viral titers and permits the production of high titer infectious chimeric reporter viruses. [PDF]

PLoS ONE, 2012
The unique properties of the hepatitis C virus (HCV) JFH1 isolate have made it possible to produce and study HCV in an infectious cell culture system. However, relatively low virus titers restrict some of the uses of this system and preparing infectious ...
Shuanghu Liu, Li Xiao, Cassie Nelson, Curt H Hagedorn   +3 more
doaj   +1 more source

Multimodality reporter gene imaging: Construction strategies and application

Theranostics, 2018
Molecular imaging has played an important role in the noninvasive exploration of multiple biological processes. Reporter gene imaging is a key part of molecular imaging.
Mengting Li, Yichun Wang, Mei Liu, X. Lan   +3 more
semanticscholar   +1 more source