Results 61 to 70 of about 542,740 (308)

Green Fluorescent Protein (GFP) in Vector Systems Played Sense Role of Epigenetic in Plants [PDF]

, 2008
The green fluorescent protein (GFP) of jellyfish (_Aequorea victoria_) has significant advantages over other reporter genes, because expression can be detected in living cells without any substrates.
Hany A. El-Shemy, Masao Ishimoto, Mutasim M. Khalafalla   +2 more
core   +1 more source

Reporter Genes

, 2008
Reporter genes have been widely used in plant molecular biology, typically to discern patterns of gene expression, but also as markers of transformed cells during stable transformation procedures.The ideal marker gene would be expected to display characteristics such as ease and cheapness of use, lack of toxicity, and robustness; and the most commonly ...
openaire   +2 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Non-invasive imaging using reporter genes altering cellular water permeability

Nature Communications, 2016
Magnetic resonance imaging combined with molecular reporters can visualise cellular functions in intact organisms. Here Mukherjeeet al. present a cellular imaging approach based on intracellular changes in water diffusion using human aquaporin 1 gene as ...
Arnab Mukherjee, Di Wu, Hunter C. Davis, Mikhail G. Shapiro   +3 more
doaj   +1 more source

Microfluorometer Assay to Measure the Expression of β-Galactosidase and Green Fluorescent Protein Reporter Genes in Single Drosophila Flies

BioTechniques, 2001
β-galactosidase and green fluorescent protein (GFP) are among the most commonly used reporter genes to monitor gene expression in various organisms including Drosophila melanogaster.
A.C. Jung, M.-C. Criqui, S. Rutschmann, J.A. Hoffmann, D. Ferrandon   +4 more
doaj   +1 more source

Invariant Distribution of Promoter Activities in Escherichia coli [PDF]

, 2009
Cells need to allocate their limited resources to express a wide range of genes. To understand how Escherichia coli partitions its transcriptional resources between its different promoters, we employ a robotic assay using a comprehensive reporter strain ...
A Zaslaver, A Zaslaver, Adrian Jinich, AL Barabasi, Alon Zaslaver, Anat Bren, Avi Mayo, BP Cormack, C Furusawa, Christopher Rao, Erez Dekel, FC Neidhardt, G Churchward, H Bremer, H Bremer, H Jeong, HR Ueda, IM Keseler, JM Carlson, JM Carlson, M Ehrenberg, M Nomura, M Schaechter, MA Kohanski, MA Kohanski, NJ Guido, NO Kjeldgaard, NO Kjeldgaard, O Maaloe, O Maaloe, PP Dennis, R Schleif, R Tanaka, R Tanaka, S Kaplan, S Klumpp, S Lin-Chao, Shai Kaplan, Shalev Itzkovitz, Uri Alon, W Donachie   +40 more
core   +4 more sources

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

Comparison between Effects of Retroactivity and Resource Competition upon Change in Downstream Reporter Genes of Synthetic Genetic Circuits

Life, 2019
Reporter genes have contributed to advancements in molecular biology. Binding of an upstream regulatory protein to a downstream reporter promoter allows quantification of the activity of the upstream protein produced from the corresponding gene.
Takefumi Moriya, Tomohiro Yamaoka, Yuki Wakayama, Shotaro Ayukawa, Zicong Zhang, Masayuki Yamamura, Shinji Wakao, Daisuke Kiga   +7 more
doaj   +1 more source

Ancient Pbx-Hox signatures define hundreds of vertebrate developmental enhancers [PDF]

, 2011
Background: Gene regulation through cis-regulatory elements plays a crucial role in development and disease. A major aim of the post-genomic era is to be able to read the function of cis-regulatory elements through scrutiny of their DNA sequence ...
Bronner, Marianne E., Elgar, Greg, Parker, Hugo J., Piccinelli, Paul, Sauka-Spengler, Tatjana   +4 more
core   +5 more sources

The chicken gene nomenclature committee report [PDF]

BMC Genomics, 2009
Comparative genomics is an essential component of the post-genomic era. The chicken genome is the first avian genome to be sequenced and it will serve as a model for other avian species. Moreover, due to its unique evolutionary niche, the chicken genome can be used to understand evolution of functional elements and gene regulation in mammalian species.
Burt, D. W., Carre, W., Fell, Mark, Law, A. S., Antin, P. B., Maglott, D. R., Weber, J. A., Schmidt, C. J., Burgess, S. C., McCarthy, F. M.   +9 more
openaire   +3 more sources