Results 21 to 30 of about 750,648 (173)

Regulation of Male Fertility by X‐Linked Genes [PDF]

Journal of Andrology, 2010
ABSTRACT: Infertility is a worldwide reproductive health problem, affecting men and women about equally. Mouse genetic studies demonstrate that more than 200 genes specifically or predominantly regulate fertility. However, few genetic causes of infertility in humans have been identified.
Ke, Zheng, Fang, Yang, Peijing Jeremy, Wang   +2 more
openaire   +2 more sources

Data for identification of porcine X-chromosome inactivation center, XIC, by genomic comparison with human and mouse XIC

Data in Brief, 2015
The data included in this article shows homologies of genes in porcine X-chromosome inactivation center, XIC, to each orthologue in human and mouse XIC.
Jae Yeon Hwang, Kwang-Hwan Choi, Chang-Kyu Lee   +2 more
doaj   +1 more source

Masculinization of the X-chromosome in aphid soma and gonads

Peer Community Journal, 2022
Males and females share essentially the same genome but differ in their optimal values for many phenotypic traits, which can result in intra-locus conflict between the sexes.
Jaquiéry, Julie, Simon, Jean-Christophe, Robin, Stéphanie, Richard, Gautier, Peccoud, Jean, Boulain, Hélène, Legeai, Fabrice, Tanguy, Sylvie, Prunier-Leterme, Nathalie, Letrionnaire, Gaël   +9 more
doaj   +1 more source

A familial case of diffuse periventricular nodular heterotopia identified prenatally: Filamin A defect as the probable cause

Radiology Case Reports
Periventricular nodular heterotopia (PNH) is a neuronal migration defect characterized by the presence of ectopic grey matter nodules adjacent to the walls of the lateral ventricles.
Mariana Tomásio Neves, MD, André Luís Borges, MD, Guilherme Martins, MD, Graça Sá, MD, Teresa Loureiro, PhD, Oana Moldovan, MD   +5 more
doaj   +1 more source

The X chromosome and sex-specific effects in infectious disease susceptibility

Human Genomics, 2019
The X chromosome and X-linked variants have largely been ignored in genome-wide and candidate association studies of infectious diseases due to the complexity of statistical analysis of the X chromosome.
Haiko Schurz, Muneeb Salie, Gerard Tromp, Eileen G. Hoal, Craig J. Kinnear, Marlo Möller   +5 more
doaj   +1 more source

Transcriptional regulation of dosage compensation in Carica papaya

Scientific Reports, 2021
Sex chromosome evolution results in the disparity in gene content between heterogametic sex chromosomes and creates the need for dosage compensation to counteract the effects of gene dose imbalance of sex chromosomes in males and females. It is not known
Juan Liu, Jennifer Han, Anupma Sharma, Ching Man Wai, Ray Ming, Qingyi Yu   +5 more
doaj   +1 more source

LOCALISATION OF THE X-LINKED HYPOPHOSPHATAEMIC RICKETS GENE [PDF]

Pediatric Research, 1986
Cloned human X chromosome fragments identifying DNA sequence polymorphisms have been used as genetic markers in linkage studfes to localise the abnormal gene that causes X-linked hypophospbataemic rickets. These linkage studies were performed in 11 families in which the disease had occured in 3 or more generations.
Thakker, R, Davies, K, Read, A, Glorieux, F, Oriordan, J   +4 more
openaire   +2 more sources

X-Linked Retinitis Pigmentosa Gene Therapy: Preclinical Aspects

Ophthalmology and Therapy, 2022
The most common inherited eye disease is retinitis pigmentosa (RP). X-linked RP (XLRP) is one of the most severe types of RP, with a considerable disease burden. Patients with XLRP experience a decrease in their vision and become blind in their 4th decade of life, causing much morbidity after starting a rather normal life.
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Abnormal dosage compensation of reporter genes driven by the Drosophila glass multiple reporter (GMR) enhancer-promoter. [PDF]

PLoS ONE, 2011
In Drosophila melanogaster the male specific lethal (MSL) complex is required for upregulation of expression of most X-linked genes in males, thereby achieving X chromosome dosage compensation.
Corey Laverty, Fang Li, Esther J Belikoff, Maxwell J Scott   +3 more
doaj   +1 more source