Results 21 to 30 of about 919,210 (312)

Evolutionary strata on the X chromosomes of the dioecious plant Silene latifolia: Evidence from new sex-linked genes [PDF]

, 2007
Despite its recent evolutionary origin, the sex chromosome system of the plant Silene latifolia shows signs of progressive suppression of recombination having created evolutionary strata of different X-Y divergence on sex chromosomes. However, even after
Bergero, Roberta, Forrest, Alan, Kamau, Esther, Charlesworth, Deborah   +3 more
core   +1 more source

Deficiency in the multicopy Sycp3-like X-linked genes Slx and Slxl1 causes major defects in spermatid differentiation. [PDF]

, 2010
The human and mouse sex chromosomes are enriched in multicopy genes required for postmeiotic differentiation of round spermatids into sperm. The gene Sly is present in multiple copies on the mouse Y chromosome and encodes a protein that is required for ...
Ojarikre, Obah A., Burgoyne, Paul S, Yamauchi, Yasuhiro, Rattigan, Aine, Julie Cocquet, Jonathan M. Riel, Thomas P. S. Karacs, Áine Rattigan, Yasuhiro Yamauchi, Riel, Jonathan M., Cocquet, Julie, Affara, Nabeel A., Monika A. Ward, Paul S. Burgoyne, Karacs, Thomas P.S., Ellis, Peter J.I., Obah A. Ojarikre, Peter J. I. Ellis, Nabeel A. Affara, Ward, Monika A.   +19 more
core   +1 more source

X chromosome inactivation during Drosophila spermatogenesis [PDF]

, 2007
Genes with male- and testis-enriched expression are under-represented on the Drosophila melanogaster X chromosome. There is also an excess of retrotransposed genes, many of which are expressed in testis, that have “escaped” the X chromosome and moved to ...
Baines, J., Hense, Winfried, Parsch, John, John Parsch, Baines, John F., Parsch John, Hense Winfried, Baines John F, Hense, W., John F Baines, Winfried Hense, Parsch, J.   +11 more
core   +1 more source

Lack of global meiotic sex chromosome inactivation, and paucity of tissue-specific gene expression on the Drosophila X chromosome

BMC Biology, 2011
Background Paucity of male-biased genes on the Drosophila X chromosome is a well-established phenomenon, thought to be specifically linked to the role of these genes in reproduction and/or their expression in the meiotic male germline.
Nurminsky Dmitry I, Mikhaylova Lyudmila M   +1 more
doaj   +1 more source

MHC-linked and un-linked class I genes in the wallaby [PDF]

, 2009
Background: MHC class I antigens are encoded by a rapidly evolving gene family comprising classical and non-classical genes that are found in all vertebrates and involved in diverse immune functions.
Wong, Emily S. W., Penny Coggill, Yuanyuan Cheng, Deakin Janine E, Katherine Belov, Hart, E., Janine E Deakin, Jennifer Harrow, Harrow Jennifer, Deakin, J.E., Cheng, Y., Beck, Stephan, Stephan Beck, Cheng, Yuanyuan, Hart, Elizabeth, Wong, Emily, Coggill, P., Deakin, Janine; id_orcid, Beck Stephan, Siddle, Hannah, Belov, K., Deakin, Janine E., Wong Emily SW, Hart Elizabeth, Wong, Emily Sw, Coggill Penny, Siddle, Hannah V., Wong, E.S.W., Coggill, Penny, Hannah V Siddle, Elizabeth Hart, Harrow, Jennifer, Beck, S., Cheng Yuanyuan, Harrow, J., Siddle Hannah V, Emily SW Wong, Belov Katherine, Siddle, H.V., Belov, Katherine   +39 more
core   +1 more source

A genetic basis for a postmeiotic X versus Y chromosome intragenomic conflict in the mouse. [PDF]

, 2012
Intragenomic conflicts arise when a genetic element favours its own transmission to the detriment of others. Conflicts over sex chromosome transmission are expected to have influenced genome structure, gene regulation, and speciation.
Shantha K. Mahadevaiah (94714), Nabeel A. Affara (135531), Vaiman, Daniel, Julie Cocquet, Nabeel A Affara, Burgoyne, Paul S., Daniel Vaiman, Cocquet, Julie, Affara, Nabeel A., Julie Cocquet (135523), Mahadevaiah, Shantha K., Ellis, Peter J.I., Peter J I Ellis, Shantha K Mahadevaiah, Daniel Vaiman (83223), Paul S. Burgoyne (94717), Peter J. I. Ellis (135526), Paul S Burgoyne   +17 more
core   +1 more source

Intelligence Quotient Variability in Klinefelter Syndrome Is Associated With GTPBP6 Expression Under Regulation of X-Chromosome Inactivation Pattern

Frontiers in Genetics, 2021
Klinefelter syndrome (KS) displays a broad dysmorphological, endocrinological, and neuropsychological clinical spectrum. We hypothesized that the neurocognitive dysfunction present in KS relies on an imbalance in X-chromosome gene expression. Thus, the X-
Luciane Simonetti, Lucas G. A. Ferreira, Lucas G. A. Ferreira, Angela Cristina Vidi, Angela Cristina Vidi, Janaina Sena de Souza, Ilda S. Kunii, Maria Isabel Melaragno, Claudia Berlim de Mello, Gianna Carvalheira, Magnus R. Dias da Silva, Magnus R. Dias da Silva   +11 more
doaj   +1 more source

LOCALISATION OF THE X-LINKED HYPOPHOSPHATAEMIC RICKETS GENE [PDF]

Pediatric Research, 1986
Cloned human X chromosome fragments identifying DNA sequence polymorphisms have been used as genetic markers in linkage studfes to localise the abnormal gene that causes X-linked hypophospbataemic rickets. These linkage studies were performed in 11 families in which the disease had occured in 3 or more generations.
Thakker, R, Davies, K, Read, A, Glorieux, F, Oriordan, J   +4 more
openaire   +2 more sources

Androgen-induced rhox homeobox genes modulate the expression of AR-regulated genes [PDF]

, 2010
Rhox5, the founding member of the reproductive homeobox on the X chromosome (Rhox) gene cluster, encodes a homeodomain-containing transcription factor that is selectively expressed in Sertoli cells, where it promotes the survival of male germ cells ...
Hu, Z.Y., Hu, Z., Verhoeven, G., De Gendt, K., Dandekar, D., Wilkinson, M.F., Wilkinson, M., O'Shaughnessy, P.J.   +7 more
core   +1 more source

Over-expression of XIST, the Master Gene for X Chromosome Inactivation, in Females With Major Affective Disorders

EBioMedicine, 2015
Background: Psychiatric disorders are common mental disorders without a pathological biomarker. Classic genetic studies found that an extra X chromosome frequently causes psychiatric symptoms in patients with either Klinefelter syndrome (XXY) or Triple X
Baohu Ji, Kerin K. Higa, John R. Kelsoe, Xianjin Zhou   +3 more
doaj   +1 more source