Results 111 to 120 of about 11,860,410 (381)

Self-cooling of a movable mirror to the ground state using radiation pressure

open access: yes, 2007
We show that one can cool a micro-mechanical oscillator to its quantum ground state using radiation pressure in an appropriately detuned cavity (self-cooling).
A. Dantan   +6 more
core   +1 more source

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

open access: yesFEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

open access: yesNature, 2022
V. Trubetskoy   +433 more
semanticscholar   +1 more source

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

open access: yesFEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang   +2 more
wiley   +1 more source

Foxg1 deletion impairs the development of the epithalamus

open access: yesMolecular Brain, 2018
The epithalamus, which is dorsal to the thalamus, consists of the habenula, pineal gland and third ventricle choroid plexus and plays important roles in the stress response and sleep–wake cycle in vertebrates.
Bin Liu   +3 more
doaj   +1 more source

Genes and salt tolerance: bringing them together.

open access: yesNew Phytologist, 2005
Salinity tolerance comes from genes that limit the rate of salt uptake from the soil and the transport of salt throughout the plant, adjust the ionic and osmotic balance of cells in roots and shoots, and regulate leaf development and the onset of ...
R. Munns
semanticscholar   +1 more source

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Gap-enhanced Raman tags for physically unclonable anticounterfeiting labels

open access: yesNature Communications, 2020
Physical unclonable functions with inherent randomness are promising candidates for secure labeling systems. Here the authors demonstrate such a function using gap-enhanced Raman tags to create high-capacity and high-security labels for ...
Yuqing Gu   +5 more
doaj   +1 more source

Lamprey watershed education and outreach [PDF]

open access: yes, 2010
The Lamprey River Nomination Committee sought the assistance of the Piscataqua Region Estuaries Partnership (PREP) to complete an extensive and detailed information package to nominate the Lamprey River and its major tributaries to the NH Rivers ...
Genes, Dawn   +2 more
core   +1 more source

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