Results 131 to 140 of about 12,090,697 (382)
FEBS Letters, EarlyView.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
AnimalsDirect-fed microbials (DFMs) have shown the potential to improve livestock performance and overall health. Extensive research has been conducted to identify new DFMs and understand their mechanisms of action in the gut.
Raphaële Gresse +9 more
doaj +1 more source
THE MUTATION RATE OF THE GENE FOR HAEMOPHILIA, AND ITS SEGREGATION RATIOS IN MALES AND FEMALES [PDF]
, 1946 J. B. S. Haldane
openalex +1 more source
The diversity of a distributed genome in bacterial populations
, 2010 The distributed genome hypothesis states that the set of genes in a population of bacteria is distributed over all individuals that belong to the specific taxon. It implies that certain genes can be gained and lost from generation to generation.
Baumdicker, F. +2 more
core +1 more source
Genome Biology, 2017 Background Respiratory illness caused by viral infection is associated with the development and exacerbation of childhood asthma. Little is known about the effects of respiratory viral infections in the absence of illness.
Agata Wesolowska-Andersen +13 more
doaj +1 more source
Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
FEBS Letters, EarlyView.Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri +5 more
wiley +1 more source
Self-cooling of a movable mirror to the ground state using radiation pressure
, 2007 We show that one can cool a micro-mechanical oscillator to its quantum ground state using radiation pressure in an appropriately detuned cavity (self-cooling).
A. Dantan +6 more
core +1 more source