Results 41 to 50 of about 1,803,838 (293)
, 2019 11 páginasBackground: Congenital leptin deficiency is a recessive genetic disorder associated with severe early-onset obesity. It is caused by mutations in the leptin (LEP) gene, which encodes the protein product leptin.
Hernan Yupanqui-Lozno +5 more
core +1 more source
Whole metagenome profiles of particulates collected from the International Space Station
Microbiome, 2017 Background The built environment of the International Space Station (ISS) is a highly specialized space in terms of both physical characteristics and habitation requirements.
Nicholas A. Be +6 more
doaj +1 more source
Caracterização genotípica dos isolados de Escherichia coli provenientes de frangos de corte
Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2011 Caracterizaram-se genotipicamente os isolados de Escherichia coli oriundos de fígado de frangos provenientes de dois matadouros avícolas. Foram coletadas 62 amostras de fígados de frangos, sendo 30 macroscopicamente inalterados e 32 com alteração ...
I.M.M. Silva +5 more
doaj +1 more source
Scientific Reports, 2023 With the advent of long-term human habitation in space and on the moon, understanding how the built environment microbiome of space habitats differs from Earth habitats, and how microbes survive, proliferate and spread in space conditions, is becoming ...
Anna C. Simpson +10 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Microbiome, 2022 Background Antimicrobial resistance (AMR) has a detrimental impact on human health on Earth and it is equally concerning in other environments such as space habitat due to microgravity, radiation and confinement, especially for long-distance space travel.
Pedro Madrigal +7 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
ISS-derived B. contaminans enriched functions as compared to references.
, 2020 ISS-derived B. contaminans enriched functions as compared to references.
Michael D. Lee (562262) +4 more
core +1 more source
Journal of Applied Poultry Research, 2016 Colibacillosis, an important disease of poultry caused by avian pathogenic Escherichia coli (APEC), is responsible for great economic losses in the poultry industry around the world. The aims of the present study were to investigate the prevalence of the increased serum survival (iss) gene and to compare the clonal distribution and relatedness of the ...
Badouei, Mahdi Askari +4 more
openaire +4 more sources
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source