Results 51 to 60 of about 47,618 (305)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Caracterização genotípica dos isolados de Escherichia coli provenientes de frangos de corte

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2011
Caracterizaram-se genotipicamente os isolados de Escherichia coli oriundos de fígado de frangos provenientes de dois matadouros avícolas. Foram coletadas 62 amostras de fígados de frangos, sendo 30 macroscopicamente inalterados e 32 com alteração ...
I.M.M. Silva, J. Evêncio-Neto, R.M. Silva, N. Lucena-Silva, J. Magalhães, M. Baliza   +5 more
doaj   +1 more source

Machine learning algorithm to characterize antimicrobial resistance associated with the International Space Station surface microbiome

Microbiome, 2022
Background Antimicrobial resistance (AMR) has a detrimental impact on human health on Earth and it is equally concerning in other environments such as space habitat due to microgravity, radiation and confinement, especially for long-distance space travel.
Pedro Madrigal, Nitin K. Singh, Jason M. Wood, Elena Gaudioso, Félix Hernández-del-Olmo, Christopher E. Mason, Kasthuri Venkateswaran, Afshin Beheshti   +7 more
doaj   +1 more source

Genome-wide search for strabismus susceptibility loci. [PDF]

, 2003
The purpose of this study was to search for chromosomal susceptibility loci for comitant strabismus. Genomic DNA was isolated from 10mL blood taken from each member of 30 nuclear families in which 2 or more siblings are affected by either esotropia or ...
Fujiwara, Hirotake, Hasebe, Satoshi, Kitada, Mizue, Matsuo, Toshihiko, Ohtsuki, Hiroshi, Sato, Masako, Yamane, Takashi   +6 more
core   +1 more source

Cloning, expression and sequence diversity of iss gene from avian pathogenic Escherichia coli (APEC) isolated in Brazil /
Clonagem, expressão e diversidade na seqüência do gene iss de Escherichia coli patogênica para aves (APEC), isolada no Brasil

Semina: Ciências Agrárias, 2010
A proteína Iss (increased serum survival) é uma importante característica de resistência ao sistema complemento da Escherichia coli patogênica para aves (APEC). Os objetivos deste trabalho foram clonar e verificar a diversidade da seqüência do gene iss de APEC e caracterizar a proteína Iss recombinante.
Marilda Carlos Vidotto, Emerson José Venâncio, Renata Katsuko Takayama Kobayashi, Ana Angelita Sampaio Baptista   +3 more
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A Novel Bioinformatic Approach to Understanding Addiction [PDF]

, 2017
Finding the genetic markers that influence complex, multigenic substance addiction phenotypes has been an area of significant medical study. Understanding complex disease traits like addiction has been hampered by the lack of functional insights into ...
Jackson, Latifa F.
core   +1 more source

Skeletal muscle myopenia in mice model of bile duct ligation and carbon tetrachloride-induced liver cirrhosis [PDF]

, 2017
Skeletal muscle myopathy is universal in cirrhotic patients, however, little is known about the main mechanisms involved. The study aims to investigate skeletal muscle morphological, histological, and functional modifications in experimental models of ...
Ascenzi, Francesca, Barberi, Laura, Caporaso, Nicola, D'Argenio, Giuseppe, Di Sario, Francesca, Gaudio, Eugenio, Giusto, Michela, Merli, Manuela, Musaro', Antonio, Nicoletti, Carmine, Renzi, Anastasia, Rizzuto, Emanuele   +11 more
core   +1 more source

Cloning, expression and sequence diversity of iss gene from avian pathogenic Escherichia coli (APEC) isolated in Brazil

Semina: Ciências Agrárias, 2010
The Iss (Increased serum survival) protein is an important characteristic of resistance to complement system of avian pathogenic Escherichia coli (APEC). The objectives of this work were to cloning and verify the sequence diversity of iss gene from APEC and characterize the recombinant Iss protein. The iss gene of 309 bp was amplified by PCR,
Ana Angelita Sampaio Baptista, Renata Katsuko Takayama Kobayashi, Emerson José Venâncio, Marilda Carlos Vidotto   +3 more
openaire   +2 more sources

Colimetric index and virulence genes iss and iutA in Escherichia coli isolates in cellulitis of poultry carcasses under sanitary inspection [PDF]

Revista Brasileira de Saúde e Produção Animal, 2018
SUMMARY Current study determines the population of total coliforms and Escherichia coli and identifies iss and iutA virulence genes in Escherichia coli strains isolated from cellulitis in poultry carcasses retrieved from a slaughterhouse. One hundred cellulitis lesions were collected between August 2013 and January 2014.
Silva, Ricardo Mendes da, Jesus, Maykson Costa de, Macêdo, Kelly Menezes, Cardoso, Vaneza Leal, Santana, Jerusa Mota, Silva, Isabella de Matos Mendes da, Baliza, Marcílio, Evêncio-Neto, Joaquim   +7 more
openaire   +3 more sources