Results 51 to 60 of about 250,803 (252)

APPLICATION OF THE DIRECTED MUTATION TO CELLULAR AUTOMATA GENERATION PROCESS [PDF]

open access: yesНаучно-технический вестник информационных технологий, механики и оптики, 2014
Cellular automata are widely used for the simulation of discrete systems. However, in most cases creation of controlling cellular automata is done manually, empirically or by exhaustive search. A number of papers describe methods for automatic generation
A. V. Tikhomirov, A. A. Shalyto
doaj  

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Co-evolutionary Genetic Algorithms for Reactive Scheduling

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2010
Previous researches provided a reactive scheduling method using a genetic algorithm to improve disturbed production schedules, due to unexpected disruptions, such as delays of manufacturing operations.
Yoshitaka TANIMIZU   +4 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

A coarse-grained parallelization of genetic algorithms

open access: yesIJAIN (International Journal of Advances in Intelligent Informatics), 2018
Genetic algorithms are frequently used to solve optimization problems. However, the problems become increasingly complex and time consuming. One solution to speed up the genetic algorithm processing is to use parallelization. The proposed parallelization
Muhamad Radzi Rathomi, Reza Pulungan
doaj   +1 more source

A Genetic Algorithm for the Maximum 2–Packing Set Problem

open access: yesInternational Journal of Applied Mathematics and Computer Science, 2020
Given an undirected connected graph G = (V, E), a subset of vertices S is a maximum 2-packing set if the number of edges in the shortest path between any pair of vertices in S is at least 3 and S has the maximum cardinality.
Trejo-Sánchez Joel Antonio   +2 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Higher-Order Quantum-Inspired Genetic Algorithms [PDF]

open access: yesAnnals of computer science and information systems, 2014
Robert Nowotniak, Jacek Kucharski
doaj   +1 more source

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