Results 51 to 60 of about 8,029,668 (390)

Driving Cars by Means of Genetic Algorithms [PDF]

open access: yes, 2008
Proceedings of: 10th International Conference on Parallel Problem Solving From Nature, PPSN 2008. Dortmund, Germany, September 13-17, 2008The techniques and the technologies supporting Automatic Vehicle Guidance are an important issue.
Isasi, Pedro   +3 more
core   +2 more sources

Molecular insights into the modulation of the 5HT2A receptor by serotonin, psilocin, and the G protein subunit Gqα

open access: yesFEBS Letters, Volume 599, Issue 6, Page 876-891, March 2025.
We explore 5HT2A receptor activation, a key target for psychedelic drugs, using molecular dynamics simulations. Without Gqα, the active receptor collapses to an inactive conformation, underscoring the G‐protein's role. Discovery of an intermediate “partially‐open” state and the higher affinity of ligands to the orthosteric binding site provides ...
Niklas Viohl   +2 more
wiley   +1 more source

Parameter Selection in Genetic Algorithms [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2004
In this study, we provide a new taxonomy of parameters of genetic algorithms (GA), structural and numerical parameters, and analyze the effect of numerical parameters on the performance of GA based simulation optimization applications with experimental ...
Onur BOYABATLI, Ihsan SABUNCUOGLU
doaj  

ASSESSING SOFTWARE RELIABILITY USING GENETIC ALGORITHMS

open access: yesThe Journal of Engineering Research, 2019
The role of software reliability and quality improvement is becoming more important than any other issues related to software development. To date, we have various techniques that give a prediction of software reliability like neural networks, fuzzy ...
Rachna Jain, Arun Sharma
doaj   +1 more source

Optimal Recombination in Genetic Algorithms [PDF]

open access: yes, 2013
This paper surveys results on complexity of the optimal recombination problem (ORP), which consists in finding the best possible offspring as a result of a recombination operator in a genetic algorithm, given two parent solutions.
Eremeev, Anton V., Kovalenko, Julia V.
core  

The apo LETM1 F‐EF‐hand adopts a closed conformation that underlies a multi‐modal sensory role in mitochondria

open access: yesFEBS Letters, Volume 599, Issue 7, Page 971-988, April 2025.
We present the first solution structure of the Ca2+‐depleted LETM1 F‐EF‐hand through a D676A/N678A Ca2+ binding‐deficient mutant, revealing a closed hydrophobic cleft caused by a unique F1‐helix pivot. The apo LETM1 F‐EF‐hand exhibits regiospecific hot and cold unfolding, sensitivity to physiological pH changes and potential for promiscuous heterotypic
Qi‐Tong Lin   +2 more
wiley   +1 more source

Multidimensional crossover in genetic algorithms

open access: yesJournal of Numerical Analysis and Approximation Theory, 1999
Not available.
Márton-Ernö Balázs
doaj   +2 more sources

Qualified Genetic Algorithms for Images Smoothing [PDF]

open access: yesالمجلة العراقية للعلوم الاحصائية, 2008
Four types of algorithms are suggested in this paper to smooth images; three of them work in the special domain and the fourth works in the frequency domain.
doaj   +1 more source

Distinct dysregulated pathways in sporadic and Lynch syndrome‐associated colorectal cancer offer insights for targeted treatment

open access: yesFEBS Letters, Volume 599, Issue 7, Page 1006-1028, April 2025.
This study explores the distinct molecular mechanisms underlying Lynch syndrome‐associated and sporadic colorectal cancer (CRC). By highlighting the therapeutic potential of targeting the PI3K‐Akt pathway in Lynch syndrome‐associated CRC and the Wnt pathway in sporadic CRC, the findings open avenues for personalised treatment strategies, aiming to ...
May J. Krause   +2 more
wiley   +1 more source

Self-selection of evolutionary strategies: adaptive versus non-adaptive forces

open access: yesHeliyon, 2021
The evolution of complex genetic networks is shaped over the course of many generations through multiple mechanisms. These mechanisms can be broken into two predominant categories: adaptive forces, such as natural selection, and non-adaptive forces, such
Matthew Putnins, Ioannis P. Androulakis
doaj  

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