Results 231 to 240 of about 115,560 (262)

West African Genetic Ancestry and Breast Cancer Outcomes Among Black Women.

JAMA Netw Open
Reid S, Fan R, Venton L, Weidner A, Tezak A, Roberson ML, Vadaparampil S, Wang X, Yoder S, Rosa M, Hirbo J, Whisenant JG, Pietenpol J, Rajagopal PS, Lehmann B, Ye F, Pal T.   +16 more
europepmc   +1 more source

West African Genetic Ancestry, Neighborhood Deprivation, and Prostate Cancer.

JAMA Netw Open
Pichardo CM, Ezeani A, Acevedo AM, Agurs-Collins T, Bailey-Whyte M, Dorsey TH, Harris AR, Franklin J, Kittles RA, Lawrence WR, Loffredo CA, Minas TZ, Pichardo MS, Ryan BM, Tang W, Wooten W, Liu J, Ambs S.   +17 more
europepmc   +1 more source

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Genetic Ancestry Inference for Pharmacogenomics

2022
Genetic ancestry inference can be used to stratify patient cohorts and to model pharmacogenomic variation within and between populations. We provide a detailed guide to genetic ancestry inference using genome-wide genetic variant datasets, with an emphasis on two widely used techniques: principal components analysis (PCA) and ADMIXTURE analysis.
I King, Jordan, Shivam, Sharma, Shashwat Deepali, Nagar, Augusto, Valderrama-Aguirre, Leonardo, Mariño-Ramírez   +4 more
openaire   +2 more sources

Ancestry and Genetics

2023
Abstract This chapter discusses how genetic diversity is related to ethnicity and ancestry and how the concept of “race” is socially constructed and without a clear biological basis. It describes the pioneering work by Richard Lewontin demonstrating that the vast majority of genetic variation is between individuals in a population rather
openaire   +1 more source

Colorectal Cancer Genomics by Genetic Ancestry

Cancer Discovery, 2022
Summary: Understanding molecular features of colorectal cancer across diverse populations is an indispensable step toward reducing the pronounced disparities in this disease burden. Based on the findings that individuals of African ancestry have an observed increase in the frequency of KRAS, AOC, and PIK3CA mutations, Myer and ...
Cathy Eng, Andreana N. Holowatyj
openaire   +2 more sources

Genetic ancestry and the search for personalized genetic histories

Nature Reviews Genetics, 2004
Public demand and the development of large public and private databases of genetic information across human populations has encouraged the development of the new and rapidly growing field of genetic ancestry testing. Both the promise of the science that underlies this field and a lack of a full understanding of its limitations have fuelled the ...
Mark D, Shriver, Rick A, Kittles
openaire   +2 more sources

The Legitimacy of Genetic Ancestry Tests

Science, 2008
I found the Policy Forum “The science and business of genetic ancestry testing” (D. A. Bolnick et al. , 19 October 2007, p. [399][1]) to be a shallow discussion of a very complex topic. Bolnick et al.
openaire   +2 more sources

Genealogical and Genetic Ancestry

2023
Abstract This chapter begins by defining genealogical ancestry and genetic ancestry, and it explains the differences between the two concepts. Then it explains why DNA ancestry testing cannot provide a complete account of a person’s ancestry.
openaire   +1 more source

Leveraging genetic ancestry to study health disparities

American Journal of Physical Anthropology, 2021
Ken Batai, Rick Kittles
exaly