Results 1 to 10 of about 144,784 (158)
Accurate genome-wide phasing from IBD data
BMC Bioinformatics, 2022 As genotype databases increase in size, so too do the number of detectable segments of identity by descent (IBD): segments of the genome where two individuals share an identical copy of one of their two parental haplotypes, due to shared ancestry.
Keith Noto, Luong Ruiz
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Prostate cancer genetic risk and associated aggressive disease in men of African ancestry
Nature Communications, 2023 African ancestry is a significant risk factor for prostate cancer and advanced disease. Yet, genetic studies have largely been conducted outside the context of Sub-Saharan Africa, identifying 278 common risk variants contributing to a multiethnic ...
Pamela X. Y. Soh +11 more
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Genome-wide risk prediction of common diseases across ancestries in one million people
Cell Genomics, 2022 Summary: Polygenic risk scores (PRS) measure genetic disease susceptibility by combining risk effects across the genome. For coronary artery disease (CAD), type 2 diabetes (T2D), and breast and prostate cancer, we performed cross-ancestry evaluation of ...
Nina Mars +19 more
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Individual‐based simulations of genome evolution with ancestry: The GenomeAdmixR R package
Methods in Ecology and Evolution, 2021 Hybridization between populations or species results in a mosaic of the two parental genomes. This and other types of genome admixture have received increasing attention for their implications in speciation, human evolution, Evolve and Resequence (E&R ...
Thijs Janzen, Fernando Diaz
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The Ancestry of Segmentation [PDF]
Developmental Cell, 2003 Recent studies of segmentation in the spider suggest that the ancestral vertebrate and arthropod segmentation mechanisms utilized the Notch signaling pathway and bolster the argument that segmentation is an ancestral feature of all bilaterians.
openaire +2 more sources
eLife, 2018 The same genes and signalling pathways control the formation of skin appendages in both fish and land animals.
Hannah Brunsdon, E Elizabeth Patton
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