Results 221 to 230 of about 115,560 (262)

Genetic geographies: the trouble with ancestry

New Genetics and Society, 2017
openaire   +2 more sources

VDAC1 Upregulation Induces Hyperexcitability of Nociceptive Sensory Neurons Via Enhanced Mitochondrial Atp Efflux in Neuropathic Pain

Advanced Science, EarlyView.
The mechanism diagram of VDAC1 mediating neuronal excitability and neuropathic pain. Briefly, VDAC1 is expressed in DRG neurons and is upregulated following CCI‐induced neuropathic pain. This upregulation enhances ATP transport from mitochondria to the cytoplasm in sensory neurons, leading to increased neuronal excitability and pain behavior.
Fengrun Sun, Ning Yu, Liang Yu, Xiaofen Tian, Yujia Ma, Yikuan Xie, Tao Wang, Chao Ma   +7 more
wiley   +1 more source

Markedly Lower Rates of Age-Related Macular Degeneration in Malta Compared to European Countries: Results from The Malta Eye Study, Indicating Possible Divergent Genetic Ancestry? [PDF]

Clin Ophthalmol
Agius D, Mamo JJ, Calleja N, Cassar D, Marku X, Nappa MC, Zammit M, Pace ME, Carbonaro F.   +8 more
europepmc   +1 more source

Clarity for the language of race, ethnicity and genetic ancestry in rheumatology. [PDF]

Nat Rev Rheumatol
Ramos PS, Lim SS.
europepmc   +1 more source

High-throughput proteomics identifies inflammatory proteins associated with disease severity and genetic ancestry in patients with hidradenitis suppurativa. [PDF]

Br J Dermatol
Dimitrion PM, Krevh R, Veenstra J, Ge J, Siddiqui A, Ferguson D, Hans A, Zuniga B, Sidhu K, Daveluy S, Hamzavi I, Zhou L, Adrianto I, Mi QS.   +13 more
europepmc   +1 more source

<i>CYP2C9</i> Promoter Variable Number Tandem Repeat Polymorphism in a Dominican Population: Exploring Differences with Genetic Ancestry. [PDF]

Genes (Basel)
de la Cruz CG, Guevara M, Rodrigues-Soares F, Rodríguez E, Peñas-Lledó E, LLerena A, Dorado P.   +6 more
europepmc   +1 more source

Genetic Ancestry-Based Differences in Biomarker-Based Eligibility for Precision Oncology Therapies.

JAMA Oncol
Arora K, Suehnholz SP, Zhang H, Ostrovnaya I, Kundra R, Nandakumar S, Nissan MH, Brannon AR, Bandlamudi C, Ladanyi M, Drilon A, Brown CL, Solit DB, Schultz N, Berger MF, Chakravarty D.   +15 more
europepmc   +1 more source

African Genetic Ancestry, Structural and Social Determinants of Health, and Mortality in Black Adults.

JAMA Netw Open
Iyer HS, Cheng I, Opara C, Lin K, Zeinomar N, Le Marchand L, Wilkens L, Shariff-Marco S, Conti DV, Haiman CA, Gomez SL, Rebbeck TR.   +11 more
europepmc   +1 more source