Results 141 to 150 of about 8,825,337 (378)

Mining Frequent Itemsets Using Genetic Algorithm

open access: yes, 2010
In general frequent itemsets are generated from large data sets by applying association rule mining algorithms like Apriori, Partition, Pincer-Search, Incremental, Border algorithm etc., which take too much computer time to compute all the frequent ...
Biswas, Sushanta   +3 more
core   +2 more sources

Novel and unscrutinized immune entities of the zebrafish gut

open access: yesFEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil   +5 more
wiley   +1 more source

Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways

open access: yesNature Genetics, 2018
Neuroticism is an important risk factor for psychiatric traits, including depression1, anxiety2,3, and schizophrenia4–6. At the time of analysis, previous genome-wide association studies7–12 (GWAS) reported 16 genomic loci associated to neuroticism10–12.
M. Nagel   +17 more
semanticscholar   +1 more source

Lack of association between VNTR polymorphism of dopamine transporter gene (SLC6A3) and schizophrenia in a Brazilian sample Ausência de associação entre o polimorfismo VNTR do gene do transportador de dopamina (SLC6A3) e esquizofrenia em uma população brasileira

open access: yesArquivos de Neuro-Psiquiatria, 2004
A role of dopaminergic dysfunction has been postulated in the aetiology of schizophrenia. We hypothesized that variations in the dopamine transporter gene (SLC6A3) may be associated with schizophrenia.
Quirino Cordeiro   +4 more
doaj   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

Association of Genetic and Environmental Factors With Autism in a 5-Country Cohort.

open access: yesJAMA psychiatry, 2019
Importance The origins and development of autism spectrum disorder (ASD) remain unresolved. No individual-level study has provided estimates of additive genetic, maternal, and environmental effects in ASD across several countries. Objective To estimate
Dan Bai   +21 more
semanticscholar   +1 more source

Conservation of Animal Genetic Resources in the Danubian Valley

open access: yesScientific Papers Animal Science and Biotechnologies, 2023
The overall aim of gene conservation is the preservation of animal genetic resources (AnGR). Since the well balanced, diverse and healthy supply of food is a major element of the national food sovereignty, hence successful animal production is not ...
Pal Hajas
doaj  

Lack of association between the G681C polimorphism in the 5-HT1Dbeta autoreceptor gene and schizophrenia Ausência de associação entre o polimorfismo G861C do gene do auto-receptor 5-HT1Dbeta e esquizofrenia

open access: yesArquivos de Neuro-Psiquiatria, 2005
A major role of the serotonergic system has been hypothesized in the pathogenesis of schizophrenia, mostly based on the evidence of action of atypical antipsychotics.
Quirino Cordeiro, Homero Vallada
doaj   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

open access: yesFEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura   +8 more
wiley   +1 more source

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