Results 241 to 250 of about 2,718,862 (371)

Elucidating shared genetic association between female body mass index and preeclampsia. [PDF]

Commun Biol
Yang F, Zha Z, Gao F, Wang M, Du E, Wang Z, Zhou L, Gao B, Li S, Zhang D.   +9 more
europepmc   +1 more source

The IL9R region contribution in asthma is supported by genetic association in an isolated population [PDF]

, 2000
Paula Kauppi, Tarja Laitinen, Vesa Ollikainen, Heikki Mannila, Lauri A. Laitinen, Juha Kere   +5 more
openalex   +1 more source

Hijacking the BAF complex: the mechanistic interplay of ARID1A and EWS::FLI1 in Ewing sarcoma

Molecular Oncology, Volume 19, Issue 4, Page 961-964, April 2025.
Ewing sarcoma is driven by the EWS::FLI1 fusion protein, which disrupts gene expression by hijacking the BAF complex via ARID1A. ARID1A's ability to form biomolecular condensates is crucial for tumor growth, making it a potential therapeutic target. However, targeting these transient condensates is challenging, requiring further research. Ewing sarcoma,
Erich J. Sohn, David S. Libich
wiley   +1 more source

Genetic association studies using disease liabilities from deep neural networks. [PDF]

Am J Hum Genet
Yang L, Sadler MC, Altman RB.
europepmc   +1 more source

Genomic landscape and preclinical models of angiosarcoma

Molecular Oncology, Volume 19, Issue 4, Page 965-983, April 2025.
Angiosarcomas are a rare and aggressive cancer with a poor prognosis for patients. The genomic landscape of angiosarcoma can be highly complex and heterogenous; however, recent studies have identified some common features especially within anatomic and molecular subgroups.
Annaleigh Benton, Bozhi Liu, Lauren E. Gartenhaus, Jason A. Hanna   +3 more
wiley   +1 more source

Missing Regulation Between Genetic Association and Transcriptional Abundance for Hypercholesterolemia Genes. [PDF]

Genes (Basel)
Hakim A, Connally NJ, Schnitzler GR, Cho MH, Jiang ZG, Sunyaev SR, Gupta RM.   +6 more
europepmc   +1 more source

Association between the Endogenous Retrovirus HRES-1 and Multiple Sclerosis in the United Kingdom – Evidence of Genetically Different Disease Subsets? [PDF]

, 2000
Henrik Berg Rasmussen, M. A. Kelly, D. A. Francis, J. Clausen   +3 more
openalex   +1 more source

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

Molecular Oncology, Volume 19, Issue 5, Page 1386-1403, May 2025.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale, Li Li, J. Kyle Bruner, Melody Chou, Bao Nguyen, Jaesung Seo, Ruiqi Zhu, Mark J. Levis, Christine A. Pratilas, Donald Small   +9 more
wiley   +1 more source

Investigating the Genetic Association of Selected Candidate Loci with Alopecia Areata Susceptibility in Jordanian Patients. [PDF]

Medicina (Kaunas)
Al-Eitan LN, Alasmar MK, Aljamal HA, Mihyar AH, Alghamdi MA.   +4 more
europepmc   +1 more source

Epidemiological and Genetic Associations of Activated Factor XII Concentration With Factor VII Activity, Fibrinopeptide A Concentration, and Risk of Coronary Heart Disease in Men [PDF]

, 2000
Francesco Paolo Zito, Felicity Drummond, Sarah R. Bujac, M. P. Esnouf, James H. Morrissey, Steve E. Humphries, George J. Miller   +6 more
openalex   +1 more source