Results 21 to 30 of about 7,627,088 (344)

Heritability estimates of the position and number of facial hair whorls in Thoroughbred horses

open access: yesBMC Research Notes, 2019
Objective According to oral traditions of horse caretakers and trainers, the differences in the position and number of facial hair whorls may be associated with temperamental traits.
Tamu Yokomori   +7 more
doaj   +1 more source

Detection of phosphorothioated (PS) oligonucleotides in horse plasma using a product ion (m/z 94.9362) derived from the PS moiety for doping control

open access: yesBMC Research Notes, 2018
Objective Clinical research on gene therapy has advanced the field of veterinary medicine, and gene doping, which is the illegal use of gene therapy, has become a major concern in horseracing. Since the International Federation of Horseracing Authorities
Teruaki Tozaki   +8 more
doaj   +1 more source

FinnGen provides genetic insights from a well-phenotyped isolated population

open access: yesNature, 2023
Genome-wide association studies of individuals from an isolated population (data from the Finnish biobank study FinnGen) and consequent meta-analyses facilitate the identification of previously unknown coding variant associations for both rare and common
M. Kurki   +167 more
semanticscholar   +1 more source

Association of the NEGR1 rs2815752 with obesity and related traits in Pakistani females

open access: yesUpsala Journal of Medical Sciences, 2020
Introduction: The variant NEGR1 rs2815752 has recently been linked with obesity in Caucasians. However, a very limited number of studies have examined the association of the NEGR1 rs2815752 with overweight/obesity in non-Caucasians with no such study ...
Sobia Rana, Maha Mobin
doaj   +1 more source

Genetic model misspecification in genetic association studies [PDF]

open access: yesBMC Research Notes, 2017
The underlying model of the genetic determinant of a trait is generally not known with certainty a priori. Hence, in genetic association studies, a dominant model might be erroneously modelled as additive, an error investigated previously. We explored this question, for candidate gene studies, by evaluating the sample size required to compensate for ...
Amadou Gaye, Sharon K. Davis
openaire   +3 more sources

A review of kernel methods for genetic association studies

open access: yesGenetic Epidemiology, 2019
Evaluating the association of multiple genetic variants with a trait of interest by use of kernel‐based methods has made a significant impact on how genetic association analyses are conducted. An advantage of kernel methods is that they tend to be robust
N. Larson, Jun Chen, D. Schaid
semanticscholar   +1 more source

MetaGenyo: a web tool for meta-analysis of genetic association studies

open access: yesBMC Bioinformatics, 2017
Genetic association studies (GAS) aims to evaluate the association between genetic variants and phenotypes. In the last few years, the number of this type of study has increased exponentially, but the results are not always reproducible due to ...
Jordi Martorell-Marugán   +3 more
semanticscholar   +1 more source

The VNTR 48 bp Polymorphism in the DRD4 Gene Is Associated with Higher Tobacco Smoking in Male Mexican Mestizo Smokers with and without COPD

open access: yesDiagnostics, 2019
Cigarette smoking is influenced by nicotine’s effects on dopaminergic activity, which appear to be moderated by genetic variation, particularly a variable number tandem repeat (VNTR, 48 bp) polymorphism in the third exon of the dopamine receptor ...
Gloria Pérez-Rubio   +7 more
doaj   +1 more source

Genome-wide association analysis of plasma lipidome identifies 495 genetic associations

open access: yesmedRxiv, 2023
Human plasma lipidome captures risk for cardio-metabolic diseases. To discover new lipid-associated variants and understand link between lipid species and cardiometabolic disorders, we performed univariate and multivariate genome-wide analyses of 179 ...
L. Ottensmann   +8 more
semanticscholar   +1 more source

Conservation of Animal Genetic Resources in the Danubian Valley

open access: yesScientific Papers Animal Science and Biotechnologies, 2023
The overall aim of gene conservation is the preservation of animal genetic resources (AnGR). Since the well balanced, diverse and healthy supply of food is a major element of the national food sovereignty, hence successful animal production is not ...
Pal Hajas
doaj  

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