Results 21 to 30 of about 8,590,328 (320)
No genetic causal association between systemic lupus erythematosus and COVID-19
Frontiers in Immunology, 2023 ObjectiveEmerging evidence suggests an increased prevalence of coronavirus disease 2019 (COVID-19) in patients with systemic lupus erythematosus (SLE), the prototype of autoimmune disease, compared to the general population. However, the conclusions were
Shu-Zhen Xu +11 more
doaj +1 more source
Genetics of autistic disorders : review and clinical implications [PDF]
, 2009 Twin and family studies in autistic disorders (AD) have elucidated a high heritability of AD. In this literature review, we will present an overview on molecular genetic studies in AD and highlight the most recent findings of an increased rate of copy ...
Duketis, Eftichia +4 more
core +4 more sources
Nature Genetics, 2017 In genome-wide association studies (GWAS) for thousands of phenotypes in large biobanks, most binary traits have substantially fewer cases than controls.
W. Zhou +18 more
semanticscholar +1 more source
Introduction to Genetic Association Studies [PDF]
Cold Spring Harbor Protocols, 2012 Genetic association studies are used to find candidate genes or genome regions that contribute to a specific disease by testing for a correlation between disease status and genetic variation. This article provides a broad outline of the design and analysis of such studies, focusing on case–control studies in candidate genes or regions.
Lewis, Cathryn M, Knight, Jo
openaire +4 more sources
Evolution: Education and Outreach, 2019 To realize the promise of the Next Generation Science Standards, educators require new three-dimensional, phenomenon-based curriculum materials. We describe and report on pilot test results from such a resource—Evolution: DNA and the Unity of Life ...
Sheila A. Homburger +16 more
doaj +1 more source
Heritability estimates of the position and number of facial hair whorls in Thoroughbred horses
BMC Research Notes, 2019 Objective According to oral traditions of horse caretakers and trainers, the differences in the position and number of facial hair whorls may be associated with temperamental traits.
Tamu Yokomori +7 more
doaj +1 more source
Population stratification and genetic association studies in South Asia [PDF]
, 2005 Population stratification and its influence on genetic association studies is a controversial topic. Although it has been suggested that stratification is unlikely to bias the results of association studies conducted in developed countries, convincing ...
Bittles, A.H.
core +2 more sources
Genetic Association Studies [PDF]
Circulation, 2008 With the completion of the HapMap project1 and the development of technology that allows the examination of ≥1 million genetic polymorphisms at once, genetic association studies are becoming more comprehensive. This article first provides a brief overview of the rationale for genetic association studies; it then discusses the primary features ...
openaire +2 more sources
Genetic association studies in Thorax [PDF]
Thorax, 2005 A guide to assessing the validity of genetic association studies in respiratory disease Increasing knowledge regarding the extent of genetic variation in the human genome has led to an explosion of interest in performing genetic association studies in complex diseases.
John D Blakey, Ian P. Hall
openaire +2 more sources
Genetics of Anthracycline-Associated Cardiotoxicity
Frontiers in Cardiovascular Medicine, 2022 Anthracyclines are a major component of chemotherapies used in many pediatric and adult malignancies. Anthracycline-associated cardiotoxicity (ACT) is a dose-dependent adverse effect that has substantial impact on morbidity and mortality. Therefore, the identification of genetic variants associated with increased risk of ACT has the potential for ...
Talal Khalid Al-Otaibi +3 more
openaire +3 more sources