Results 41 to 50 of about 2,782,325 (342)

Association analysis of Epworth Sleepiness Scale (ESS) scores with serotonin transporter (5-HTT- LPR, 5-HTT-VNTR) and circadian (PER3-VNTR) genes [PDF]

Sleep Science
Excessive daytime sleepiness (EDS) is a common complaint encountered in clinical practice with serious consequences both for individual and society since it can increase the ratio of motor vehicle accidents, work- related incidents, and deaths. Moreover,
Filiz Ozen, Zeynep Yegin, Zuhal Aydan Saglam, Figen Yavlal, Haydar Koc, Celal Ulasoglu   +5 more
doaj   +1 more source

Genomic copy number variation association study in Caucasian patients with nonsyndromic cryptorchidism [PDF]

, 2016
Copy number variation (CNV) is a potential contributing factor to many genetic diseases. Here we investigated the potential association of CNV with nonsyndromic cryptorchidism, the most common male congenital genitourinary defect, in a Caucasian ...
Abrams, Debra J., Banihani, Ahmad H., Barthold, Julia Spencer, Chiavacci, Rosetta M., Devoto, Marcella, Figueroa, T. Ernesto, Gonzalez, Ricardo, Hagerty, Jennifer A., Hakonarson, Hakon, Harden, Kisha R., Kim, Cecilia E., Kolon, Thomas F., Li, Jin, Noh, Paul H., Olivant Fisher, Alicia, Sol Church, Katia, Stabley, Deborah, Wang, Yanping   +17 more
core   +1 more source

Why and When Are Evidence‐Based Interventions Adopted in Paediatric Supportive Care? A Qualitative Exploration of the Determinants of Photobiomodulation Implementation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Oral mucositis is a common and debilitating side effect of childhood cancer and stem cell transplant treatments. It affects the quality of life of children and young people (CYP) and places a strain on services. Photobiomodulation is recommended for oral mucositis prevention in international guidance but is poorly implemented in UK ...
Claudia Heggie, Kara A. Gray‐Burrows, Peter F. Day, Bob Phillips, Carl A. Thompson   +4 more
wiley   +1 more source

Exploring genetic associations of Crohn’s disease and ulcerative colitis with extraintestinal cancers in European and East Asian populations

Frontiers in Immunology
BackgroundPrevious studies have reported associations of Crohn’s disease (CD) and ulcerative colitis (UC) with the risks of extraintestinal cancers, but the causality remains unclear.MethodsUsing genetic variations robustly associated with CD and UC ...
Chengdong Yu, Jiawei Xu, Siyi Xu, Lei Tang, Qinyuan Han, Xiaoqiang Zeng, Yanxiao Huang, Tenghua Yu, Zhengkui Sun   +8 more
doaj   +1 more source

Genetic association studies [PDF]

Neurology, 2001
The urge to associate genetic markers with human traits or diseases has been around for centuries. The association of specific hair colors with certain personality types has a long tradition in folklore. The rate-limiting factor has been the availability of measurable genetic markers.
Thomas D. Bird, Gail P. Jarvik, Nicholas W. Wood   +2 more
openaire   +1 more source

GemTools: A fast and efficient approach to estimating genetic ancestry [PDF]

, 2011
To uncover the genetic basis of complex disease, individuals are often measured at a large number of genetic variants (usually SNPs) across the genome. GemTools provides computationally efficient tools for modeling genetic ancestry based on SNP genotypes.
Devlin, Bernie, Kent, Brian P., Klei, Lambertus, Melhem, Nadine, Roeder, Kathryn   +4 more
core  

Genome-wide analyses for personality traits identify six genomic loci and show correlations with psychiatric disorders [PDF]

, 2016
Personality is influenced by genetic and environmental factors1 and associated with mental health. However, the underlying genetic determinants are largely unknown.
A Okbay, A Ramasamy, AE Poropat, Anders M Dale, Andrew Schork, B Bulik-Sullivan, B Devlin, B Franke, B Howie, BK Bulik-Sullivan, BM Henn, C Giambartolomei, CA Rietveld, Carol Franz, CG DeYoung, Chi-Hua Chen, Chun-Chieh Fan, CJ Soto, CJ Willer, D Falush, D Trabzuni, Daniel J Smith, David A Hinds, DF Gudbjartsson, DJ Smith, Dominic Holland, DP Hibar, DR Nyholt, E Green, G Bjornsdottir, Gyda Bjornsdottir, HC So, HN Kim, Hreinn Stefansson, J Van Os, J Yang, JA Gray, JH Barnett, JK Pickrell, JM Hettema, Joyce Y Tung, JR Gulcher, K Åberg, Kari Stefansson, Karolina Kauppi, KS Kendler, L Mezquita, Linda K McEvoy, LR Goldberg, MA Distel, MH de Moor, MH de Moor, Michael O'Donovan, Min-Tzu Lo, Nilotpal Sanyal, Olav B Smeland, Ole A Andreassen, P Bůžková, R Plomin, R Tabarés-Seisdedos, RA Power, RA Power, RJ Pruim, S Jakobwitz, S Purcell, S Ripke, SBG Eysenck, SL Karalunas, SM van den Berg, SM van den Berg, SR Browning, T Insel, T Vukasović, TA Greenwood, Thorgeir E Thorgeirsson, TJ Trull, V Boraska, Valentina Escott-Price, WK Thompson, Y Hu, Y Ono, Y Wang, Yunpeng Wang   +82 more
core   +3 more sources

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Genome-wide association study of primary open-angle glaucoma in continental and admixed African populations. [PDF]

, 2018
Primary open angle glaucoma (POAG) is a complex disease with a major genetic contribution. Its prevalence varies greatly among ethnic groups, and is up to five times more frequent in black African populations compared to Europeans.
Akafo, Stephen K, Allingham, R Rand, Ashaye, Adeyinka O, Belbin, Gillian M, Bonnemaijer, Pieter WM, Bottinger, Erwin P, Cook, Colin, Eyes of Africa Genetics Consortium, GIGA Study Group, Girkin, Christopher A, Hammond, Christopher J, Hassan, Hassan G, Hauser, Michael A, Hysi, Pirro G, Iglesias, Adriana I, Kenny, Eimear E, Klaver, Caroline CW, Lemij, Hans G, Li, Zheng, Loos, Ruth JF, Meester-Smoor, Magda A, Nadkarni, Girish N, Nag, Abhishek, NEIGHBORHOOD Consortium, Ng, Maggie CY, Rotter, Jerome I, Sanyiwa, Anna J, Schurmann, Claudia, Simcoe, Mark, Taylor, Kent D, Thiadens, Alberta AHJ, van de Laar, Suzanne, van Duijn, Cornelia M, Weinreb, Robert N, Wiggs, Janey L, Wiliams, Susan EI, Zangwill, Linda M   +36 more
core  

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine, Ofélie Trudeau‐Ferrin, Caroline Laverdière, Patrick Hamel, Rosanne Superstein, Bénédicte Koukoui, Carole Provost, Paul C. Nathan, Vijay Ramaswamy, Furqan Shaikh, Brenda Gallie, Ashwin Mallipatna, Stephanie Kletke, Helen Dimaras, Hallie Coltin   +14 more
wiley   +1 more source