Results 11 to 20 of about 2,782,325 (342)

Development and pilot testing of a three-dimensional, phenomenon-based unit that integrates evolution and heredity

Evolution: Education and Outreach, 2019
To realize the promise of the Next Generation Science Standards, educators require new three-dimensional, phenomenon-based curriculum materials. We describe and report on pilot test results from such a resource—Evolution: DNA and the Unity of Life ...
Sheila A. Homburger, Dina Drits-Esser, Molly Malone, Kevin Pompei, Kagan Breitenbach, Ryan D. Perkins, Pete C. Anderson, Nicola C. Barber, Amy J. Hawkins, Sam Katz, Max Kelly, Harmony Starr, Kristin M. Bass, Jo Ellen Roseman, Joseph Hardcastle, George DeBoer, Louisa A. Stark   +16 more
doaj   +1 more source

Genetic Association Studies [PDF]

Circulation, 2008
With the completion of the HapMap project1 and the development of technology that allows the examination of ≥1 million genetic polymorphisms at once, genetic association studies are becoming more comprehensive. This article first provides a brief overview of the rationale for genetic association studies; it then discusses the primary features ...
openaire   +2 more sources

The role of 39 psoriasis risk variants on age of psoriasis onset. [PDF]

, 2013
Recent genome-wide association studies (GWAS) have identified multiple genetic risk factors for psoriasis, but data on their association with age of onset have been marginally explored.
Butler, Daniel, Chen, Haoyan, Cordoro, Kelly, Debbaneh, Maya, Gupta, Rishu, Huynh, Monica, Kane, Sinae, Leon, Argentina, Levin, Ethan, Liao, Wilson, Lu, Yingchang, Millsop, Jillian W, Nguyen, Tien   +12 more
core   +2 more sources

Heritability estimates of the position and number of facial hair whorls in Thoroughbred horses

BMC Research Notes, 2019
Objective According to oral traditions of horse caretakers and trainers, the differences in the position and number of facial hair whorls may be associated with temperamental traits.
Tamu Yokomori, Teruaki Tozaki, Hiroshi Mita, Takeshi Miyake, Hironaga Kakoi, Yuki Kobayashi, Kanichi Kusano, Takuya Itou   +7 more
doaj   +1 more source

Detection of phosphorothioated (PS) oligonucleotides in horse plasma using a product ion (m/z 94.9362) derived from the PS moiety for doping control

BMC Research Notes, 2018
Objective Clinical research on gene therapy has advanced the field of veterinary medicine, and gene doping, which is the illegal use of gene therapy, has become a major concern in horseracing. Since the International Federation of Horseracing Authorities
Teruaki Tozaki, Kaoru Karasawa, Yohei Minamijima, Hideaki Ishii, Mio Kikuchi, Hironaga Kakoi, Kei-ichi Hirota, Kanichi Kusano, Shun-ichi Nagata   +8 more
doaj   +1 more source

Genetic components in diabetic retinopathy

Indian Journal of Ophthalmology, 2016
Diabetic retinopathy (DR) is a serious complication of diabetes, which is fast reaching epidemic proportions worldwide. While tight glycemic control remains the standard of care for preventing the progression of DR, better insights into DR etiology ...
Bibhudatta Mishra, Anand Swaroop, Raj P Kandpal   +2 more
doaj   +1 more source

PsychArray-Based Genome Wide Association Study of Suicidal Deaths in India

Brain Sciences, 2023
Background: Suicide is a preventable but escalating global health crisis. Genome-wide association studies (GWAS) studies to date have been limited, and some are underpowered.
Chittaranjan Behera, Ruchika Kaushik, Deepak Ramkumar Bharti, Baibaswata Nayak, Daya Nand Bhardwaj, Dibyabhaba Pradhan, Harpreet Singh   +6 more
doaj   +1 more source

Genetic model misspecification in genetic association studies [PDF]

BMC Research Notes, 2017
The underlying model of the genetic determinant of a trait is generally not known with certainty a priori. Hence, in genetic association studies, a dominant model might be erroneously modelled as additive, an error investigated previously. We explored this question, for candidate gene studies, by evaluating the sample size required to compensate for ...
Amadou Gaye, Sharon K. Davis
openaire   +3 more sources

iPSCORE: A Resource of 222 iPSC Lines Enabling Functional Characterization of Genetic Variation across a Variety of Cell Types. [PDF]

, 2017
Large-scale collections of induced pluripotent stem cells (iPSCs) could serve as powerful model systems for examining how genetic variation affects biology and disease.
Adler, Eric, Aguirre, Aitor, Arias, Angelo D, Benaglio, Paola, Berggren, W Travis, Borja, Victor, Chi, Neil C, Cook, Megan, D'Antonio, Matteo, D'Antonio-Chronowska, Agnieszka, Dargitz, Carl T, DeBoever, Christopher, Diffenderfer, Kenneth E, Donovan, Margaret KR, Drees, Frauke, Evans, Sylvia M, Farnam, KathyJean, Feiring, Rachel, Frazer, Kelly A, Garcia, Melvin, Goldstein, Lawrence SB, Greenwald, William W, Grinstein, Jonathan D, Harismendy, Olivier, Hashem, Sherin I, Hishida, Yuriko, Izpisua Belmonte, Juan Carlos, Jakubosky, David A, Jepsen, Kristen, Li, He, Loring, Jeanne F, Matsui, Hiroko, McGarry, Thomas J, Miller, Carl A, Modesto, Veronica, Müller, Franz-Josef, Nariai, Naoki, Nelson, Bradley C, O'Connor, Daniel T, Okubo, Jonathan, Panopoulos, Athanasia D, Rao, Fangwen, Reyna, Joaquin, Schuldt, Bernhard M, Smith, Erin N, Williams, Roy, Yeo, Gene W, Zhao, Chang   +47 more
core   +2 more sources

Genetic Risk and Atrial Fibrillation in Patients with Heart Failure [PDF]

, 2020
Aims: To study the association between an atrial fibrillation (AF) genetic risk score with prevalent AF and all-cause mortality in patients with heart failure.
Anker, Stefan D., Artola, Vicente A., Benjamin, Emelia J., Dickstein, Kenneth, Filippatos, Gerasimos S., Kloosterman, Mariëlle, Koekemoer, Andrea, Lam, Carolyn S. P., Lang, Chim, Meer, Peter van der, Metra, Marco, Nelson, Christopher P., Ng, Leong L., Ponikowski, Piotr, Rienstra, Michiel, Romaine, Simon P. R., Roselli, Carolina, Samani, Nilesh J., Santema, Bernadet T., van der Harst, Pim, Van Gelder, Isabelle C., Van Veldhuisen, Dirk Jan, Voors, Adriaan A.   +22 more
core   +3 more sources