Results 11 to 20 of about 226,034 (265)

Within-sibship genome-wide association analyses decrease bias in estimates of direct genetic effects [PDF]

open access: yes, 2022
Estimates from genome-wide association studies (GWAS) of unrelated individuals capture effects of inherited variation (direct effects), demography (population stratification, assortative mating) and relatives (indirect genetic effects). Family-based GWAS
Howe, Laurence J.   +7 more
core   +3 more sources

Evolving temporal association rules with genetic algorithms [PDF]

open access: yes, 2010
A novel framework for mining temporal association rules by discovering itemsets with a genetic algorithm is introduced. Metaheuristics have been applied to association rule mining, we show the efficacy of extending this to another variant - temporal ...
Gongora, Mario A.   +6 more
core   +1 more source

The COPD genetic association compendium: a comprehensive online database of COPD genetic associations [PDF]

open access: yesHuman Molecular Genetics, 2009
Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. COPD is thought to arise from the interaction of environmental exposures and genetic susceptibility, and major research efforts are underway to identify genetic determinants of COPD susceptibility.
Castaldi, P.   +15 more
openaire   +3 more sources

Heritability estimates of the position and number of facial hair whorls in Thoroughbred horses

open access: yesBMC Research Notes, 2019
Objective According to oral traditions of horse caretakers and trainers, the differences in the position and number of facial hair whorls may be associated with temperamental traits.
Tamu Yokomori   +7 more
doaj   +1 more source

Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study. [PDF]

open access: yes, 2011
The prevalence of hypertension in African Americans (AAs) is higher than in other US groups; yet, few have performed genome-wide association studies (GWASs) in AA.
Keating, BJ   +999 more
core   +1 more source

Genetic components in diabetic retinopathy

open access: yesIndian Journal of Ophthalmology, 2016
Diabetic retinopathy (DR) is a serious complication of diabetes, which is fast reaching epidemic proportions worldwide. While tight glycemic control remains the standard of care for preventing the progression of DR, better insights into DR etiology ...
Bibhudatta Mishra   +2 more
doaj   +1 more source

PsychArray-Based Genome Wide Association Study of Suicidal Deaths in India

open access: yesBrain Sciences, 2023
Background: Suicide is a preventable but escalating global health crisis. Genome-wide association studies (GWAS) studies to date have been limited, and some are underpowered.
Chittaranjan Behera   +6 more
doaj   +1 more source

Genome-wide association study of receptive language ability of 12 year olds [PDF]

open access: yes, 2013
Purpose: We have previously shown that individual differences in measures of receptive language ability at age 12 are highly heritable. The current study attempted to identify some of the genes responsible for the heritability of receptive language ...
Hanscombe, K.B.   +32 more
core   +1 more source

Progress in Genetic Studies of Tourette’s Syndrome

open access: yesBrain Sciences, 2017
Tourette’s Syndrome (TS) is a complex disorder characterized by repetitive, sudden, and involuntary movements or vocalizations, called tics. Tics usually appear in childhood, and their severity varies over time.
Yanjie Qi   +3 more
doaj   +1 more source

Association of Genetic Variation With Keratoconus [PDF]

open access: yesJAMA Ophthalmology, 2020
Keratoconus is a condition in which the cornea progressively thins and protrudes in a conical shape, severely affecting refraction and vision. It is a major indication for corneal transplant. To discover new genetic loci associated with keratoconus and better understand the causative mechanism of this disease, we performed a genome-wide association ...
Bennet J, McComish   +21 more
openaire   +2 more sources

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