Results 81 to 90 of about 2,467,569 (240)

Migraine genetics: Associative studies

Nauchno-prakticheskii zhurnal «Patogenez», 2018
Статья посвящена анализу имеющихся на сегодняшний день данных генетических полиморфизмов, излучавшихся при мигрени. При мигрени гены-кандидаты мигрени сгруппированы в четыре функциональных семейства генов: гены нервной системы, гены сердечно-сосудистой системы, гормональные, воспалительные гены. Среди генов нервной системы значимость представляют гены,
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Human platelet antigen polymorphisms and the risk of chronic Chagas disease cardiomyopathy

Platelets, 2020
Human platelet antigen (HPA) polymorphisms are considered to be a risk factor for cardiac and vascular diseases, but the role of HPA in chronic Chagas disease cardiomyopathy (CCC) is not available.
Deborah Elzita do Carmo Corrêa, Christiane Maria Ayo, Jeane Eliete Laguila Visentainer, Eliane Papa Ambrosio-Albuquerque, Pâmela Guimarães Reis, Cinara Cássia Brandão de Mattos, Reinaldo Bulgarelli Bestetti, Luiz Carlos de Mattos, Ana Maria Sell   +8 more
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‘Smoking Genes’: A Genetic Association Study

PLoS ONE, 2011
Some controversy exists on the specific genetic variants that are associated with nicotine dependence and smoking-related phenotypes. The purpose of this study was to analyse the association of smoking status and smoking-related phenotypes (included nicotine dependence) with 17 candidate genetic variants: CYP2A6*1×2, CYP2A6*2 (1799T>A) [rs1801272 ...
Zoraida Verde, Catalina Santiago, José Miguel Rodríguez González-Moro, Pilar de Lucas Ramos, Soledad López Martín, Fernando Bandrés, Alejandro Lucia, Félix Gómez-Gallego   +7 more
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Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. [PDF]

, 2014
To further understanding of the genetic basis of type 2 diabetes (T2D) susceptibility, we aggregated published meta-analyses of genome-wide association studies (GWAS), including 26,488 cases and 83,964 controls of European, east Asian, south Asian and ...
Abecasis, Goncalo R, Adair, Linda S, Almgren, Peter, Asian Genetic Epidemiology Network Type 2 Diabetes (AGEN-T2D) Consortium, Atalay, Mustafa, Aung, Tin, Baldassarre, Damiano, Balkau, Beverley, Bao, Yuqian, Barnett, Anthony H, Barroso, Ines, Basit, Abdul, Been, Latonya F, Beilby, John, Bell, Graeme I, Below, Jennifer E, Benediktsson, Rafn, Bergman, Richard N, Boehm, Bernhard O, Boerwinkle, Eric, Bonnycastle, Lori L, Burtt, Noël, Cai, Qiuyin, Campbell, Harry, Carey, Jason, Cauchi, Stephane, Caulfield, Mark, Chan, Juliana CN, Chang, Li-Ching, Chang, Tien-Jyun, Chang, Yi-Cheng, Charpentier, Guillaume, Chen, Chien-Hsiun, Chen, Han, Chen, Yuan-Tsong, Chia, Kee-Seng, Chidambaram, Manickam, Chines, Peter S, Cho, Nam H, Cho, Young Min, Chuang, Lee-Ming, Chuang, Lee-Ming, Collins, Francis S, Cornelis, Marylin C, Couper, David J, Crenshaw, Andrew T, Danesh, John, Das, Debashish, de Faire, Ulf, Dedoussis, George, Deloukas, Panos, DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium, Dimas, Antigone S, Dina, Christian, Doney, Alex S, Donnelly, Peter J, Dorkhan, Mozhgan, Dupuis, Josée, Edkins, Sarah, Elliott, Paul, Emilsson, Valur, Erbel, Raimund, Eriksson, Johan G, Escobedo, Jorge, Esko, Tonu, Eury, Elodie, Ferreira, Teresa, Florez, Jose C, Fontanillas, Pierre, Forouhi, Nita G, Forsen, Tom, Fox, Caroline, Fraser, Ross M, Frayling, Timothy M, Froguel, Philippe, Frossard, Philippe, Gao, Yutang, Gaulton, Kyle J, Gertow, Karl, Gieger, Christian, Gigante, Bruna, Go, Min Jin, Grallert, Harald, Grant, George B, Groves, Chrisropher J, Grrop, Leif C, Horikoshi, Momoko, Johnson, Andrew D, Mahajan, Anubha, Mexican American Type 2 Diabetes (MAT2D) Consortium, Ng, Maggie CY, Prokopenko, Inga, Saleheen, Danish, South Asian Type 2 Diabetes (SAT2D) Consortium, Type 2 Diabetes Genetic Exploration by Nex-generation sequencing in muylti-Ethnic Samples (T2D-GENES) Consortium, van Dam, Rob M, van Duijn, Cornelia, Wang, Xu, Zeggini, Eleftheria, Zhang, Weihua   +99 more
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Simple Algorithms to Calculate Asymptotic Null Distributions of Robust Tests in Case-Control Genetic Association Studies in R [PDF]

The case-control study is an important design for testing association between genetic markers and a disease. The Cochran-Armitage trend test (CATT) is one of the most commonly used statistics for the analysis of case-control genetic association studies ...
Gang Zheng, Wing Kam Fung, Yong Zang
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Genome-wide association study of primary open-angle glaucoma in continental and admixed African populations. [PDF]

, 2018
Primary open angle glaucoma (POAG) is a complex disease with a major genetic contribution. Its prevalence varies greatly among ethnic groups, and is up to five times more frequent in black African populations compared to Europeans.
Akafo, Stephen K, Allingham, R Rand, Ashaye, Adeyinka O, Belbin, Gillian M, Bonnemaijer, Pieter WM, Bottinger, Erwin P, Cook, Colin, Eyes of Africa Genetics Consortium, GIGA Study Group, Girkin, Christopher A, Hammond, Christopher J, Hassan, Hassan G, Hauser, Michael A, Hysi, Pirro G, Iglesias, Adriana I, Kenny, Eimear E, Klaver, Caroline CW, Lemij, Hans G, Li, Zheng, Loos, Ruth JF, Meester-Smoor, Magda A, Nadkarni, Girish N, Nag, Abhishek, NEIGHBORHOOD Consortium, Ng, Maggie CY, Rotter, Jerome I, Sanyiwa, Anna J, Schurmann, Claudia, Simcoe, Mark, Taylor, Kent D, Thiadens, Alberta AHJ, van de Laar, Suzanne, van Duijn, Cornelia M, Weinreb, Robert N, Wiggs, Janey L, Wiliams, Susan EI, Zangwill, Linda M   +36 more
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Genetic susceptibility in Juvenile Myoclonic Epilepsy: Systematic review of genetic association studies.

PLoS ONE, 2017
BackgroundSeveral genetic association investigations have been performed over the last three decades to identify variants underlying Juvenile Myoclonic Epilepsy (JME).
Bruna Priscila Dos Santos, Chiara Rachel Maciel Marinho, Thalita Ewellyn Batista Sales Marques, Layanne Kelly Gomes Angelo, Maísa Vieira da Silva Malta, Marcelo Duzzioni, Olagide Wagner de Castro, João Pereira Leite, Fabiano Timbó Barbosa, Daniel Leite Góes Gitaí   +9 more
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U-statistics in genetic association studies [PDF]

Human Genetics, 2012
Many common human diseases are complex and are expected to be highly heterogeneous, with multiple causative loci and multiple rare and common variants at some of the causative loci contributing to the risk of these diseases. Data from the genome-wide association studies (GWAS) and metadata such as known gene functions and pathways provide the ...
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Replication validity of genetic association studies

Nature Genetics, 2001
The rapid growth of human genetics creates countless opportunities for studies of disease association. Given the number of potentially identifiable genetic markers and the multitude of clinical outcomes to which these may be linked, the testing and validation of statistical hypotheses in genetic epidemiology is a task of unprecedented scale.
Ioannidis, J. P., Ntzani, E. E., Trikalinos, T. A., Contopoulos-Ioannidis, D. G.   +3 more
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Data from microRNA miR-196a-2 and Breast Cancer: A Genetic and Epigenetic Association Study and Functional Analysis

, 2023
Aaron E. Hoffman, Tongzhang Zheng, Chunhui Yi, Derek Leaderer, Joanne B. Weidhaas, Frank J. Slack, Yawei Zhang, Trupti Paranjape, Yong‐Guan Zhu   +8 more
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