Results 71 to 80 of about 2,467,569 (240)
A genome-wide association study of COVID-19 related hospitalization in Spain reveals genetic disparities among sexes [PDF]
, 2021 Ãngel Carracedo
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A variance components factor model for genetic association studies: a Bayesian analysis.
, 2010 Studies of gene-trait associations for complex diseases often involve multiple traits that may vary by genotype groups or patterns. Such traits are usually manifestations of lower-dimensional latent factors or disease syndromes.
Nonyane, BAS, Whittaker, JC
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HLA Class I or Class II and Disease Association: Catch the Difference if You Can [PDF]
, 2017 The association of autoimmune diseases with HLA has been known for many decades. To date, however, the underlying mechanisms have not been fully understood. The recently introduced genome-wide association studies (GWAS) have suggested that several genes
Fiorillo, Mt +3 more
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Association of Rab37 gene polymorphism and delayed menarche: a report of 2 060 women
陆军军医大学学报Objective To explore the association between single nucleotide polymorphism (SNP) of Rab37 gene and the age at menarche(AAM). Methods A case-control study design was used to conduct an epidemiologic survey on 2 060 women in a community in Jurong City,
YUAN Meng, YUAN Meng, CAI Yang, CAI Yang
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Disease‐Concordant Twins Empower Genetic Association Studies [PDF]
Annals of Human Genetics, 2016 SummaryGenome‐wide association studies with moderate sample sizes are underpowered, especially when testing SNP alleles with low allele counts, a situation that may lead to high frequency of false‐positive results and lack of replication in independent studies.
Tan, Qihua, Li, Weilong, VANDIN, FABIO
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Frontiers in GeneticsBackground: Periodontitis and benign prostatic hyperplasia (BPH) are all common chronic diseases with higher incidence in middle-aged and old men. Several studies have indicated a potential association between periodontitis and BPH, although the findings
Haotian Wei +7 more
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Biomédica: revista del Instituto Nacional de Salud, 2017 Introduction: Systemic lupus erythematosus is an autoimmune disease in which the severity varies according to race, sex and age of onset. This variation is also observed in the genetic markers associated with the disease, including PTPN22, VDR and TNF ...
Gloria Garavito +9 more
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Accurate modeling of confounding variation in eQTL studies leads to a great increase in power to detect trans-regulatory effects [PDF]
, 2011 Expression quantitative trait loci (eQTL) studies are an integral tool to investigate the genetic component of gene expression variation. A major challenge in the analysis of such studies are hidden confounding factors, such as unobserved covariates or ...
Neil Lawrence +2 more
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Statistical significance in genetic association studies
Clinical and Investigative Medicine, 2010 Clinical & Investigative Medicine (CIM) is receiving an increasing number of reports of candidate-based association studies. The track record of such studies in the past has been poor: numerous genetic associations reported from candidate gene studies have not been replicated in later studies.
Hui-Qi, Qu +2 more
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Pooled Association Tests for Rare Genetic Variants: A Review and Some New Results
, 2014 In the search for genetic factors that are associated with complex heritable human traits, considerable attention is now being focused on rare variants that individually have small effects.
Derkach, Andriy +2 more
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