Results 91 to 100 of about 4,028,677 (349)

Interaktionen zwischen Genotyp und Ort sind ein Vorteil von lokaler Züchtung von Ackerbohnen (Vicia faba L.) [PDF]

, 2007
Organic farming is based on low productivity environments regarding the restricted supply of inputs. Thus, to maximize the response of selection, the local breeding approach was put forward for organic agriculture.
Ghaouti, L., Link, W., Vogt-Kaute, W.
core  

Genome Resources for Climate‐Resilient Cowpea, an Essential Crop for Food Security [PDF]

, 2016
Cowpea (Vigna unguiculata L. Walp.) is a legume crop that is resilient to hot and drought‐prone climates, and a primary source of protein in sub‐Saharan Africa and other parts of the developing world.
Alhakami, Hind, Alpert, Matthew, Atokple, Ibrahim, Barkley, Noelle A., Batieno, Benoit J., Boukar, Ousmane, Bozdag, Serdar, Cisse, Ndiaga, Close, Timothy J., Drabo, Issa, Ehlers, Jeffrey D., Farmer, Andrew, Fatokun, Christian, Gu, Yong Q., Guo, Yi-Ning, Huynh, Bao-Lam, Jackson, Scott A., Kusi, Francis, Lawley, Cynthia T., Lonardi, Stefano, Lucas, Mitchell R., Luo, Ming-Cheng, Ma, Yaqin, Mirebrahim, Hamid, Munoz-Amatriain, Maria, Roberts, Philip A., Timko, Michael P., Wanamaker, Steve, Wu, Jiajie, Xu, Pei, You, Frank   +30 more
core   +3 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

An overview of the current genetic and phenotypical selection strategies to reduce the prevalence of feline hypertrophic cardiomyopathy = Een overzicht van de huidige genetische en fenotypische selectiestrategieën tegen hypertrofe cardiomyopathie bij de kat [PDF]

, 2020
Hypertrophic cardiomyopathy (HCM) is a common and potentially lethal heart disease in cats. To reduce its prevalence, breeding cats are frequently screened on the basis of their phenotype or genotype.
Broeckx, Bart, Peelman, Luc, Schipper, Tom, Smets, Pascale   +3 more
core   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

The alcohol dehydrogenase gene family in sugarcane and its involvement in cold stress regulation

BMC Genomics, 2020
Background Alcohol dehydrogenases (ADHs) in plants are encoded by a multigene family. ADHs participate in growth, development, and adaptation in many plant species, but the evolution and function of the ADH gene family in sugarcane is still unclear ...
Weihua Su, Yongjuan Ren, Dongjiao Wang, Yachun Su, Jingfang Feng, Chang Zhang, Hanchen Tang, Liping Xu, Khushi Muhammad, Youxiong Que   +9 more
doaj   +1 more source

Fine-scale population structure and asymmetrical dispersal in an obligate salt-marsh passerine, the Saltmarsh Sparrow (Ammodramus Caudacutus) [PDF]

, 2012
Understanding the spatial scale of gene flow can yield valuable insight into the ecology of an organism and guide conservation strategies. Fine-scale genetic structure is uncommon in migratory passerines because of their high vagility and presumed high ...
Babbitt, Kimberly J., Kovach, Adrienne I., O\u27Brien, Kathleen M., Walsh, Jennifer   +3 more
core   +2 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Identification and evaluation of PCR reference genes for host and pathogen in sugarcane-Sporisorium scitamineum interaction system

BMC Genomics, 2018
Background Sugarcane (Saccharum L. plant) is an important crop for sugar and bio-energy production around the world. Among sugarcane diseases, smut caused by Sporisorium scitamineum is one of the major fungal diseases causing severe losses to the ...
Ning Huang, Hui Ling, Feng Liu, Yachun Su, Weihua Su, Huaying Mao, Xu Zhang, Ling Wang, Rukai Chen, Youxiong Que   +9 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source