Results 71 to 80 of about 2,685,260 (259)

Genetic variation in bovine milk fat composition [PDF]

, 2009
In her thesis, Stoop shows that there is considerable genetic variation in milk fat composition, which opens opportunities to improve milk fat composition by selective breeding.
Stoop, W.M.
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Foreign cry1Ac gene integration and endogenous borer stress-related genes synergistically improve insect resistance in sugarcane

BMC Plant Biology, 2018
Background Sugarcane (Saccharum spp. hybrids) is considered the most globally important sugar-producing crop and raw material for biofuel. Insect attack is a major issue in sugarcane cultivation, resulting in yield losses and sucrose content reductions ...
Dinggang Zhou, Xiaolan Liu, Shiwu Gao, Jinlong Guo, Yachun Su, Hui Ling, Chunfeng Wang, Zhu Li, Liping Xu, Youxiong Que   +9 more
doaj   +1 more source

Modelling Agricultural Systems: Applications to Livestock Breeding [PDF]

Traditionally the evaluation of animal genetic traits has focused primarily on production traits and the construction of selection indices. Selection indices, however, fail to consider the effect of management practices and the environment on ...
Hattam, Caroline
core  

Breeding against osteochondrosis : phenotypic and genetic analyses in horses and pigs [PDF]

, 2011
Osteochondrosis (OC) is a disturbance in the process of endochondral ossification during skeletal growth. The objectives of this thesis were to assess the prevalence and genetic parameters of OC, and to facilitate optimization of breeding against OC ...
Grevenhof, E.M., van
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Genetic trends in CIMMYT’s tropical maize breeding pipelines

, 2022
Fostering a culture of continuous improvement through regular monitoring of genetic trends in breeding pipelines is essential to improve efficiency and increase accountability.
Vivek, B., Tarekegne, A.T., Beyene, Y., Ahmed, S., Makumbi, D., Zaman-Allah, M., Chere, A.T., Burgueño, J., Nagesh, P., Kuchanur, P.H., Zaidi, P.H., Magorokosho, C., Fato, P., Dagne Wegary Gissa, Lohithaswa, H.C., Mashingaidze, K., Vinayan, M.T., Matova, P.M., Koirala, K.B., Jat, S.L., San Vicente Garcia, F.M., Rakshit, S., Cairns, J.E., Prasanna, B.M., Mwansa, K., Asea, G., Dhliwayo, T., Ndhlela, T., Singh, S.B., Kumar, R., Singh, N.K., Woyengo, V.   +31 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Alternative polyadenylation and metabolic profiling in young panicle development of hybrid rice and its parents

Rice
Alternative polyadenylation (APA) is a widespread post-transcriptional regulatory mechanism in eukaryotes that modulates gene expression by generating transcript variants.
Guangliang Wu, Shangwei Yu, Junru Fu, Linjuan Ouyang, Lifang Hu, Jianmin Bian, Xiaorong Chen, Jie Xu, Dahu Zhou, Haohua He, Haihui Fu   +10 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source