Results 71 to 80 of about 4,028,677 (349)

Community-based breeding programmes are a viable solution for Ethiopian small ruminant genetic improvement but require public and private investments.

Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie, 2019
Ethiopia has a large and diverse population of small ruminants, which contribute substantially to the livelihood and income of the rural poor and the country at large. However, the sector faces a number of challenges.
A. Haile, S. Gizaw, T. Getachew, Joaquín P Mueller, P. Amer, M. Rekik, B. Rischkowsky   +6 more
semanticscholar   +1 more source

Modern approaches for breeding high quality apples with durable resistance to scab, powdery mildew and fire blight [PDF]

, 2008
New methods to allow for more precise selection of tree and fruit characters in breeding programmes were developed in recent years. Marker-assisted selection (MAS) is common practice in the ACW apple breeding programme at Wädenswil.
Duffy, Brion, Frey, Jürg, Kellerhals, Markus, Patocchi, Andrea   +3 more
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Study on microflora structure of Macrobrachium rosenbergii larvae and environmental water at different developmental stages

Journal of Freshwater Ecology, 2022
16S rRNA gene sequencing was used to analyze the changes in the microbial community structure of Macrobrachium rosenbergii (M. rosenbergii) larvae and environmental water at different stages (0, 7, 14 and 21 days).
Yang Xu, Haihua Cheng, Zhimin Gu, Xilian Li, Peijing Shen, Qiang Gao   +5 more
doaj   +1 more source

Genetic and genomic resources for Rubus breeding: a roadmap for the future

Horticulture Research, 2019
Rubus fruits are high-value crops that are sought after by consumers for their flavor, visual appeal, and health benefits. To meet this demand, production of red and black raspberries (R. idaeus L. and R. occidentalis L.), blackberries (R. subgenus Rubus)
T. Foster, N. Bassil, M. Dossett, Margaret Leigh Worthington, J. Graham   +4 more
semanticscholar   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Optimized breeding strategies to harness genetic resources with different performance levels

bioRxiv, 2019
Background The narrow genetic base of elite germplasm compromises long-term genetic gain and increases the vulnerability to biotic and abiotic stresses in unpredictable environmental conditions. Therefore, an efficient strategy is required to broaden the
Antoine Allier, S. Teyssedre, Christina Lehermeier, L. Moreau, A. Charcosset   +4 more
semanticscholar   +1 more source

Using Microsatellites to Assess Genetic Variation in a Selective Breeding Program of Chinese Bay Scallop (Argopecten irradians irradians) [PDF]

, 2013
This study aimed to improve our understanding of the genetics of the Chinese bay scallop (Argopecten irradians irradians), one of the most important maricultured shellfish in China.
Li Li., Zhang G., Zhang S.
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Genome-wide scan reveals genetic divergence and diverse adaptive selection in Chinese local cattle

BMC Genomics, 2019
Background Understanding the population structure and genetic bases of well-adapted cattle breeds to local environments is one of the most essential tasks to develop appropriate genetic improvement programs.
Lingyang Xu, Liu Yang, Bo Zhu, Wengang Zhang, Zezhao Wang, Yan Chen, Lupei Zhang, Xue Gao, Huijiang Gao, George E. Liu, Junya Li   +10 more
doaj   +1 more source