Results 191 to 200 of about 5,981,041 (371)

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Origin of the Genetic Code

Nature, 1967
F. Crick
semanticscholar   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

<i>Chlamydomonas</i> chloroplast genes tolerate compression of the genetic code to just 51 codons. [PDF]

Proc Natl Acad Sci U S A
Mordaka PM, Clouston K, Cui J, Holzer A, Jackson HO, Purton S, Smith AG.   +6 more
europepmc   +1 more source

Impact of non-coding RNAs in genetic disease and papillomavirus lifecycle

, 2017
Rachel Chirayil
openalex   +1 more source

The Structural Basis of the Genetic Code: Amino Acid Recognition by Aminoacyl-tRNA Synthetases [PDF]

, 2019
Florian Kaiser, Sarah Krautwurst, Sebastian Salentin, V. Joachim Haupt, Christoph Leberecht, Sebastian Bittrich, Dirk Labudde, Michael Schroeder   +7 more
openalex   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

StayRose: A photostable StayGold derivative redshifted by genetic code expansion. [PDF]

J Biol Chem
Scott W, Ivorra-Molla E, Akhuli D, Massam-Wu T, Lysyganicz PK, Walsh R, Parent M, Cook J, Song L, Kumar A, Schneider F, Mishima M, Crow A, Balasubramanian MK.   +13 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Hijacking a bacterial ABC transporter for genetic code expansion. [PDF]

Nature
Iype T, Fottner M, Böhm P, Piedrafita C, Möller Y, Groll M, Lang K.   +6 more
europepmc   +1 more source