Results 51 to 60 of about 5,849,979 (303)
Overview of tRNA Modifications in Chloroplasts
Microorganisms, 2022 The chloroplast is a promising platform for biotechnological innovation due to its compact translation machinery. Nucleotide modifications within a minimal set of tRNAs modulate codon–anticodon interactions that are crucial for translation efficiency ...
Maxime Fages-Lartaud +1 more
doaj +1 more source
Life, 2018 Information is the currency of life, but the origin of prebiotic information remains a mystery. We propose transitional pathways from the cosmic building blocks of life to the complex prebiotic organic chemistry that led to the origin of information ...
S. Chatterjee, S. Yadav
semanticscholar +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Alveolar soft part sarcoma (ASPS) is a rare soft tissue sarcoma occurring most commonly in adolescence and young adulthood. Methods We present the clinical characteristics, treatments, and outcomes of patients with newly diagnosed ASPS enrolled on the Children's Oncology Group study ARST0332.
Jacquelyn N. Crane +11 more
wiley +1 more source
Life, 2016 We have previously proposed that tRNAGly was the first tRNA and glycine was the first amino acid incorporated into the genetic code. The next two amino acids incorporated would have been the other two small hydrophilic amino acids serine and aspartic ...
Harold S. Bernhardt
doaj +1 more source
Analysis of amino acids network based on transition and transversion mutation of codons [PDF]
Network Biology, 2021 In this paper, we have developed a network of 20 amino acids based on a distance matrix of amino acids. This distance matrix is obtained by considering the transition and transversion mutation of codons.
Tazid Ali, Chandra Borah
doaj
Therapeutic applications of genetic code expansion
Synthetic and Systems Biotechnology, 2018 In nature, a limited, conservative set of amino acids are utilized to synthesize proteins. Genetic code expansion technique reassigns codons and incorporates noncanonical amino acids (ncAAs) through orthogonal aminoacyl-tRNA synthetase (aaRS)/tRNA pairs.
Yujia Huang, T. Liu
semanticscholar +1 more source
Implementing Health‐Related Quality of Life Assessment in Pediatric Oncology: A Feasibility Study
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background There is growing interest in embedding health‐related quality of life (HRQoL) assessment and patient‐reported outcome measures (PROMs) within clinical cancer care. This study evaluated the feasibility, acceptability, and usability of implementing an electronic PROM (ePROM) platform to measure HRQoL in children with cancer ...
Mikaela Doig +13 more
wiley +1 more source
Next-generation genetic code expansion.
Current Opinion in Chemical Biology, 2018 Engineering of the translation apparatus has permitted the site-specific incorporation of nonstandard amino acids (nsAAs) into proteins, thereby expanding the genetic code of organisms.
Pol Arranz‐Gibert +2 more
semanticscholar +1 more source
Treatment Decision‐Making Roles and Preferences Among Adolescents and Young Adults With Cancer
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Decision‐making (DM) dynamics between adolescents and young adults (AYAs) with cancer, parents, and oncologists remain underexplored in diverse populations. We examined cancer treatment DM preferences among an ethnically and socioeconomically diverse group of AYAs and their parents.
Amanda M. Gutierrez +14 more
wiley +1 more source
Algebraic structures and distance based analysis of genetic code [PDF]
Network Biology, 2023 This paper explores the genetic code's algebraic structures associated with the four mRNA (or DNA) bases A, G, C, and U. We have obtained quotient group structures of codons by considering the transition and substitution mutation. In these quotient group
Chandra Borah, Tazid Ali
doaj