Results 51 to 60 of about 5,981,041 (371)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Purpose Infants with cancer are rare and face unique challenges. Our study aims to describe the incidence of infantile cancers in Canada and to compare treatment‐related mortality (TRM) and their outcomes with those of older children. Methods We conducted a retrospective cohort study using the Cancer in Young People in Canada database ...
Samuel Sassine +22 more
wiley +1 more source
Gaussian-Distributed Codon Frequencies of Genomes
G3: Genes, Genomes, Genetics, 2019 DNA encodes protein primary structure using 64 different codons to specify 20 different amino acids and a stop signal. Frequencies of codon occurrence when ordered in descending sequence provide a global characterization of a genome’s preference (bias ...
Bohdan B. Khomtchouk, Wolfgang Nonner
doaj +1 more source
Analysis of amino acids network based on transition and transversion mutation of codons [PDF]
Network Biology, 2021 In this paper, we have developed a network of 20 amino acids based on a distance matrix of amino acids. This distance matrix is obtained by considering the transition and transversion mutation of codons.
Tazid Ali, Chandra Borah
doaj
Genetic Code Expansion in Animals.
ACS Chemical Biology, 2018 Expanding the genetic code to enable the incorporation of unnatural amino acids into proteins in biological systems provides a powerful tool for studying protein structure and function.
Wes Brown, Jihe Liu, A. Deiters
semanticscholar +1 more source
Evaluating the Genetic Overlap Between Congenital Heart Disease and Neuroblastoma Risk
Pediatric Blood &Cancer, EarlyView.ABSTRACT Children with congenital heart disease (CHD) have elevated neuroblastoma (NB) risk, potentially due to shared neural crest origins. We analyzed rare exonic de novo single‐nucleotide variants in 702 CHD and 454 NB trios from the Neuroblastoma Epidemiology in North America Study, Gabriella Miller Kids First Program, and a published cohort. Seven
Ji Yun Tark +7 more
wiley +1 more source
Optimality of the genetic code with respect to protein stability and amino acid frequencies [PDF]
, 2001 How robust is the natural genetic code with respect to mistranslation errors? It has long been known that the genetic code is very efficient in limiting the effect of point mutation.
Cerf, Nicolas +3 more
core +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Introduction We developed MedSupport, a multilevel medication adherence intervention designed to address root barriers to medication adherence. This study sought to explore the feasibility and acceptability of the MedSupport intervention strategies to support a future full‐scale randomized controlled trial.
Elizabeth G. Bouchard +8 more
wiley +1 more source
Algebraic structures and distance based analysis of genetic code [PDF]
Network Biology, 2023 This paper explores the genetic code's algebraic structures associated with the four mRNA (or DNA) bases A, G, C, and U. We have obtained quotient group structures of codons by considering the transition and substitution mutation. In these quotient group
Chandra Borah, Tazid Ali
doaj
The functional readthrough extension of malate dehydrogenase reveals a modification of the genetic code [PDF]
Open Biology, 2016 Translational readthrough gives rise to C-terminally extended proteins, thereby providing the cell with new protein isoforms. These may have different properties from the parental proteins if the extensions contain functional domains.
Julia Hofhuis +6 more
doaj +1 more source
Expanding the genetic code of Mus musculus
Nature Communications, 2017 Here we report the expansion of the genetic code of Mus musculus with various unnatural amino acids including Nɛ-acetyl-lysine. Stable integration of transgenes encoding an engineered Nɛ-acetyl-lysyl-tRNA synthetase (AcKRS)/tRNAPyl pair into the mouse ...
Songmi Han +5 more
semanticscholar +1 more source