Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
The costs of breed reconstruction from cryopreserved material in mammalian livestock species
Genetics Selection Evolution, 2007 The aim of this work was to compare costs, in the horse, cattle, sheep, swine, and rabbit species, for the creation of gene banks for reconstruction of an extinct breed, using different strategies: embryos-only, embryos in combination with semen, and ...
Gandini Gustavo +3 more
doaj +1 more source
The WTP for property rights for the Giant Panda: can a charismatic species be an instrument for conservation of natural habitat? [PDF]
, 2002 The paper presents the results from a stated preference study to address issues concerning the potential for using flag-ship species, such as the Giant Panda, to purchase the property rights for the conservation of natural habitat. The study finds, first,
Kontoleon, A., Swanson, T.
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Next‐generation metrics for monitoring genetic erosion within populations of conservation concern
Evolutionary Applications, 2017 Genetic erosion is a major threat to biodiversity because it can reduce fitness and ultimately contribute to the extinction of populations. Here, we explore the use of quantitative metrics to detect and monitor genetic erosion.
G. Leroy +6 more
semanticscholar +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Determinants of cereal diversity in communities and on household farms of the Northern Ethiopian Highlands: [PDF]
"On farm conservation of crop diversity poses obvious policy challenges in terms of the design of appropriate incentive mechanisms and possible trade-offs between conservation and productivity.
Benin, Samuel +4 more
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Extinctions, genetic erosion and conservation options for the black rhinoceros (Diceros bicornis)
Scientific Reports, 2017 The black rhinoceros is again on the verge of extinction due to unsustainable poaching in its native range. Despite a wide historic distribution, the black rhinoceros was traditionally thought of as depauperate in genetic variation, and with very little ...
Y. Moodley +16 more
semanticscholar +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
On farm conservation of rice biodiversity in Nepal: a simultaneous estimation approach [PDF]
"This paper presents an empirical case study about farmer management of rice genetic resources in two communities of Nepal, drawing on interdisciplinary, participatory research that involved farmers, rice geneticists, and social scientists.
Gauchan, Devendra +2 more
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The concept of "Networked collection" or "Virtual collection"?: revisiting the classical delineation between "in situ" and "ex situ" conservation and its consequences on database management [PDF]
, 2009 A networked collection, also called a virtual collection, is located at more than one geographical/institutional site, spans the genetic diversity of a given species (genepool) and gathers stakeholders having a mutual interest in rationally conserving ...
Bambridge, T. +5 more
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