Results 161 to 170 of about 4,570,239 (335)

Development of a high-throughput microsatellite typing approach for forensic and population genetic analysis of wild and domestic African Bovini [PDF]

open access: yes, 2008
Conservation management and forensic traceability of African buffalo and cattle rely on the timely provision of unbiased and accurate genetic information.
Bastos, A.D.S.   +6 more
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

CROP DIVERSITY AS THE DERIVED OUTCOME OF FARMERS' 'SURVIVAL FIRST' MOTIVES IN ETHIOPIA: WHAT ROLE FOR ON-FARM CONSERVATION OF SORGHUM GENETIC RESOURCES? [PDF]

open access: yes
Crop genetic resources are the building blocks of sustainable agricultural development due to their relevance not only as inputs for variety development but also as indigenous crop insurance mechanisms through traditional variety portfolio management ...
Virchow, Detlef, Wale, Edilegnaw
core   +1 more source

Conservation of the critically endangered frog Telmatobufo bullocki in fragmented temperate forests of Chile : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Conservation Biology at Massey University, Albany, New Zealand [PDF]

open access: yes, 2015
Amphibians are currently facing several threats and are suffering severe population declines and extinction worldwide. Telmatobufo bullocki (Anura: Calyptocephalellidae) is one of the rarest and most endangered amphibian species in Chile's temperate ...
Moreno-Puig, Virginia
core  

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Computing Opportunity Costs of Growing Local Varieties for On-farm Conservation: Illustrations Using Sorghum Data from Ethiopia [PDF]

open access: yes
The recent shift of emphasis to on-farm conservation is driven by its diverse attractive features - participatory nature, dynamic nature, capacity to maintain not only crop diversity but the knowledge that evolves with it, the chance it offers and the ...
Estrella, Jaime   +2 more
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Economic Evaluation of Conservation through Use of an Araucaria angustifolia Provenance and Progeny Test

open access: yesPlants
Araucaria angustifolia is a species known for its valuable wood and nuts, but it is threatened with extinction. The plantation of forests for genetic resource conservation is a complementary strategy designed to reduce the species’ genetic variability ...
José Arimatéia Rabelo Machado   +7 more
doaj   +1 more source

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