Results 61 to 70 of about 1,867,301 (331)

A stepwise emergence of evolution in the RNA world

FEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Associations among growth, scrotal circumference, and visual score of beef cattle in performance tests on pasture or in feedlots

Revista Brasileira de Zootecnia
This study aimed to evaluate associations among final weight (FW), average daily gain (ADG), scrotal circumference (SC), and visual score (VS) of beef cattle in performance tests on pasture or in feedlots.
Fernanda Santos Silva Raidan, Juan Salvador Andrade Tineo, Mariana Mamedes de Moraes, Thiago Campos Escarce, Andresa Eva Melo de Araújo, Muller Marques de Carvalho Gomes, Henrique Torres Ventura, Fabio Luiz Buranelo Toral   +7 more
doaj   +1 more source

Direct selection on male attractiveness and female preference fails to produce a response

BMC Evolutionary Biology, 2004
Background Theoretical studies suggest that direct and indirect selection have the potential to cause substantial evolutionary change in female mate choice.
Brooks Robert, Lindholm Anna K, Hall Matthew   +2 more
doaj   +1 more source

Bivariate causal mixture model quantifies polygenic overlap between complex traits beyond genetic correlation. [PDF]

, 2019
Accumulating evidence from genome wide association studies (GWAS) suggests an abundance of shared genetic influences among complex human traits and disorders, such as mental disorders.
Andreassen, Ole A, Dale, Anders M, Djurovic, Srdjan, Fan, Chun Chieh, Frei, Oleksandr, Holland, Dominic, Maeland, Steffen, O'Connell, Kevin S, Shadrin, Alexey A, Smeland, Olav B, Thompson, Wesley K, Wang, Yunpeng   +11 more
core   +3 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Genetic Analysis of Antibody Response to Porcine Reproductive and Respiratory Syndrome Vaccination as an Indicator Trait for Reproductive Performance in Commercial Sows

Frontiers in Genetics, 2020
We proposed to investigate the genomic basis of antibody response to porcine reproductive and respiratory syndrome (PRRS) virus (PRRSV) vaccination and its relationship to reproductive performance in non-PRRSV-infected commercial sows.
Leticia P. Sanglard, Rohan L. Fernando, Kent A. Gray, Daniel C. L. Linhares, Jack C. M. Dekkers, Megan C. Niederwerder, Nick V. L. Serão   +6 more
doaj   +1 more source

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Random regression models with B-splines to estimate genetic parameters for body weight of young bulls in performance tests

Revista Brasileira de Zootecnia, 2018
The objective of this study was to estimate genetic parameters for body weight of beef cattle in performance tests. Different random regression models with quadratic B-splines and heterogeneous residual variance were fitted to estimate covariance ...
Daiane Cristina Becker Scalez, Breno de Oliveira Fragomeni, Dalinne Chrystian Carvalho dos Santos, Tiago Luciano Passafaro, Maurício Mello de Alencar, Fabio Luiz Buranelo Toral   +5 more
doaj   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source