Results 61 to 70 of about 967,622 (295)
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Czech Journal of Animal Science, 2017 Genetic relationship was analyzed between type traits and longevity measures in dual-purpose cattle. Data from 91 486 Czech Fleckvieh cows first calved between 2003 and 2009 were used.
Luboš Novotný +3 more
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Genetic overlap between major depressive disorder and obstructive sleep apnea
Frontiers in PsychiatryObjectiveObservational studies have frequently shown a co-occurrence of psychiatric disorders and Obstructive sleep apnea (OSA), with major depressive disorder (MDD) being a prevalent psychiatric disorder.
Fangbo Lin +4 more
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Genetic correlations between longevity and conformation traits in the Czech Holstein population
Czech Journal of Animal Science, 2012 Genetic correlations between longevity and conformation traits were estimated using data on Czech Holstein cows first calved in the years 1993-2008. Longevity traits considered were length of productive life and number of lactations initiated and their ...
L. Zavadilová, M. Štípková
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FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
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Journal of Dairy Science: Genetic selection to reduce CH4 emissions is a promising solution for reducing the environmental impact of dairy cattle production. Before such a selection program can be implemented, however, it is necessary to have a better understanding of the ...
S. Fresco +3 more
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Czech Journal of Animal Science, 2013 Genetic parameters for total number of piglets born per litter, number of piglets weaned per litter, lean meat content, and average daily gain from birth till the end of the field test were estimated for Czech Large White (445 589 records) and Czech ...
E. Krupa, J. Wolf
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Quambalaria shoot blight resistance in marri (Corymbia calophylla): genetic parameters and correlations between growth rate and blight resistance [PDF]
, 2022 Hoa Thanh Duong +4 more
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source