Results 81 to 90 of about 1,867,301 (331)

Genetic correlations in grapevine and their effects on selection

Australian Journal of Grape and Wine Research, 2015
Background and Aims The evaluation of genotype-by-environment interaction and the genotypic correlations between important economic traits are two relevant issues of the methodology of grapevine selection that remain insufficiently explored.
Vanda Pedroso, R. Almeida, Isabel Carrasquinho, Elsa Gonçalves, A. Martins   +4 more
openaire   +2 more sources

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source

Common Genetic Variants Explain the Majority of the Correlation Between Height and Intelligence : The Generation Scotland Study [PDF]

, 2014
Creative Commons Attribution LicensePeer reviewedPublisher ...
Archie Campbell, B Benyamin, BH Smith, BH Smith, C Gale, Caroline Hayward, CM Calvin, CM Calvin, CM Haworth, CM Lee, D Wechsler, D Wechsler, David J. Porteous, E Whitley, G Davies, G. David Batty, GD Batty, Ian J. Deary, IJ Deary, IJ Deary, J Yang, J Yang, JC Raven, JM Starr, JM Sundet, JP Beauchamp, K Silventoinen, K Silventoinen, KL Gunderson, LJ Whalley, Lynne J. Hocking, M Trzaskowski, MC Keller, MD Lezak, Peter M. Visscher, Riccardo E. Marioni, S Macgregor, SH Lee, Shona M. Kerr, SM Kerr, TA Paajanen   +40 more
core   +3 more sources

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

FEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield, Torsten Kleffmann, David J. Saul, Sigurd M. Wilbanks   +3 more
wiley   +1 more source

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

FEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker, Nimit Mistry, Nicoletta Plotegher, Elizabeth R. Westbrook, Michael D. E. Sewell, John Carroll, Gyorgy Szabadkai, Angus J. Bain, Michael R. Duchen   +8 more
wiley   +1 more source

Genetic correlations between production and disease traits during first lactation in Holstein cows

Animal, 2014
The aim of this study was to estimate genetic correlations between milk yield, somatic cell score (SCS), mastitis, and claw and leg disorders (CLDs) during first lactation in Holstein cows by using a threshold–linear random regression test-day model.
K. Hagiya, T. Yamazaki, Y. Nagamine, K. Togashi, S. Yamaguchi, Y. Gotoh, T. Kawahara, Y. Masuda, M. Suzuki   +8 more
doaj   +1 more source

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

FEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi, Takehiro Suzuki, Ryota Kawahara, Natsumi Harai, Naoshi Dohmae, Siro Simizu   +5 more
wiley   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Genetic association for oil yield and its component traits in different Ocimum species [PDF]

Electronic Journal of Plant Breeding, 2012
The genus Ocimum belonging to family Lamiaceae is a medicinal aromatic plant that produces essential oils used for various aromatic and medicinal purposes.
R. Ramesh Kumar , , L. Prasanna Anjaneya Reddy and Rajendra Prasad Patel
doaj  

Genetic parameters for traits evaluated at field tests of 3- and 4-year-old Swedish Warmblood horses

Animal, 2008
There are two types of 1-day field tests available for young Swedish Warmblood sport horses; one test for 3-year olds and one more advanced test for 4-year olds. Conformation, gaits and jumping ability are evaluated at both tests.
Å. Viklund, E. Thorén Hellsten, A. Näsholm, E. Strandberg, J. Philipsson   +4 more
doaj   +1 more source