Results 111 to 120 of about 5,291,009 (397)
Purification tags markedly affect self‐aggregation of CPEB3
FEBS Letters, EarlyView.Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...Harunobu Saito, Yujin Lee, Motoharu Ueno, Naotaka Sekiyama, Masatomo So, Ayako Furukawa, Kenji Sugase +6 morewiley +1 more sourceWhole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets
Nature Communications, 2015 Pancreatic ductal adenocarcinoma (PDA) has a dismal prognosis and insights into both disease etiology and targeted intervention are needed. A total of 109 micro-dissected PDA cases were subjected to whole-exome sequencing. Microdissection enriches tumour A. Witkiewicz, E. McMillan, U. Balaji, GuemHee Baek, Wan-chi Lin, J. Mansour, M. Mollaee, K. Wagner, P. Koduru, A. Yopp, M. Choti, C. Yeo, P. Mccue, M. White, E. Knudsen +14 moresemanticscholar +1 more sourceNatural recovery of genetic diversity by gene flow in reforested areas
of the endemic Canary Island pine, Pinus canariensis
, 2007 The endemic pine, Pinus canariensis, forms one of the main forest ecosystems
in the Canary Islands. In this archipelago, pine forest is a mosaic of natural
stands (remnants of past forest overexploitation) and artificial stands planted
from the 1940's ...Adams, Auckland, Brent C. Emerson, Chagné, DiFazio, Doyle, Dyer, El-Kassaby, Glaubitz, Glaubitz, Goldstein, González-Martínez, Gómez, Harju, Ledig, Ledig, Lefèvre, Lenormand, Lian, Miguel Navascués, Nathan, Nei, Nei, Nielsen, Parsons, Rannala, Raymond, Robledo-Arnuncio, Schuster, Soranzo, Vaxevanidou, Vendramin, Wang, Waples, Yazdani +34 morecore +3 more sourcesThe power of genetic diversity in genome-wide association studies of lipids
Nature, 2021 S. Graham, S. Clarke, Kuan-Han H. Wu, S. Kanoni, G. Zajac, S. Ramdas, I. Surakka, I. Ntalla, S. Vedantam, T. Winkler, A. Locke, E. Marouli, M. Y. Hwang, Sohee Han, A. Narita, A. Choudhury, A. Bentley, K. Ekoru, A. Verma, B. Trivedi, H. Martin, K. Hunt, Q. Hui, D. Klarin, Xiang Zhu, G. Thorleifsson, A. Helgadóttir, D. Gudbjartsson, H. Hólm, I. Olafsson, M. Akiyama, S. Sakaue, C. Terao, M. Kanai, Wei Zhou, B. Brumpton, H. Rasheed, S. Ruotsalainen, A. Havulinna, Y. Veturi, Q. Feng, E. Rosenthal, T. Lingren, J. Pacheco, S. Pendergrass, J. Haessler, Franco Giulianini, Y. Bradford, Jason E. Miller, A. Campbell, Kuang Lin, I. Millwood, G. Hindy, A. Rasheed, J. Faul, Wei Zhao, D. Weir, Constance Turman, Hongyan Huang, M. Graff, A. Mahajan, Michael R. Brown, Weihua Zhang, Ketian Yu, Ellen M. Schmidt, Anita Pandit, S. Gustafsson, X. Yin, J. Luan, Jinghua Zhao, F. Matsuda, Hye-Mi Jang, Kyungheon Yoon, C. Medina-Gomez, A. Pitsillides, J. Hottenga, G. Willemsen, A. Wood, Y. Ji, Zishan Gao, S. Haworth, R. Mitchell, Jin-Fang Chai, M. Aadahl, Jie Yao, A. Manichaikul, H. Warren, J. Ramírez, J. Bork-Jensen, L. Kårhus, A. Goel, M. Sabater-Lleal, R. Noordam, C. Sidore, E. Fiorillo, Aaron F. McDaid, P. Marques-Vidal, M. Wielscher, S. Trompet, N. Sattar, L. Møllehave, B. Thuesen, M. Munz, Lingyao Zeng, Jianfeng Huang, Bin Yang, A. Poveda, A. Kurbasic, C. Lamina, L. Forer, M. Scholz, T. Galesloot, J. Bradfield, E. W. Daw, J. Zmuda, J. Mitchell, C. Fuchsberger, Henry Christensen, Jennifer A. Brody, M. Feitosa, M. Wojczynski, Michael H. Preuss, M. Mangino, P. Christofidou, N. Verweij, J. Benjamins, J. Engmann, R. Kember, R. Slieker, K. S. Lo, Nuno R Zilhao, P. Le, M. Kleber, G. Delgado, Shaofeng Huo, Daisuke D Ikeda, H. Iha, Jian Yang, Jun Liu, H. Leonard, J. Marten, B. Schmidt, Marina Arendt, L. Smyth, M. Cañadas-Garre, Chaolong Wang, M. Nakatochi, A. Wong, N. Hutri-Kähönen, X. Sim, Rui Xia, A. Huerta-Chagoya, J. Fernández-López, V. Lyssenko, Meraj Ahmed, A. Jackson, M. Irvin, C. Oldmeadow, Han-Na Kim, S. Ryu, P. Timmers, L. Arbeeva, R. Dorajoo, L. Lange, Xiaoran Chai, Gauri Prasad, L. Lorés-Motta, Marc Pauper, J. Long, Xiaohui Li, E. Theusch, F. Takeuchi, Cassandra N. Spracklen, A. Loukola, S. Bollepalli, S. Warner, Y. X. Wang, W. Wei, T. Nutile, D. Ruggiero, Y. Sung, Y. Hung, Shufeng Chen, Fangchao Liu, Jingyun Yang, K. Kentistou, Mathias Gorski, M. Brumat, K. Meidtner, L. Bielak, Jennifer A. Smith, Prashantha Hebbar, Aliki-Eleni Farmaki, E. Hofer, Maoxuan Lin, C. Xue, Jifeng Zhang, M. P. Concas, S. Vaccargiu, P. J. van der Most, N. Pitkänen, B. Cade, Jiwon Lee, S. W. van der Laan, K. Chitrala, S. Weiss, M. Zimmermann, Jong Young Lee, Hyeok Sun Choi, M. Nethander, S. Freitag-Wolf, L. Southam, N. W. Rayner, Carol A. Wang, Shih-Yi Lin, Jun-Sing Wang, C. Couture, L. Lyytikäinen, K. Nikus, G. Cuéllar-Partida, H. Vestergaard, Bertha Hildalgo, O. Giannakopoulou, Q. Cai, M. Obura, J. van Setten, Xiaoyin Li, K. Schwander, N. Terzikhan, J. Shin, R. Jackson, A. Reiner, L. Martin, Zhengming Chen, Liming Li, H. Highland, K. Young, T. Kawaguchi, J. Thiery, J. Bis, G. Nadkarni, L. Launer, Huaixing Li, M. Nalls, O. Raitakari, S. Ichihara, S. Wild, C. Nelson, H. Campbell, S. Jäger, T. Nabika, F. Al-Mulla, H. Niinikoski, P. Braund, I. Kolčić, P. Kovacs, Tota Giardoglou, T. Katsuya, K. F. Bhatti, D. D. de Kleijn, G. D. de Borst, E. Kim, H. Adams, M. A. Ikram, Xiaofeng Zhu, F. Asselbergs, A. Kraaijeveld, J. Beulens, X. Shu, L. Rallidis, O. Pedersen, T. Hansen, P. Mitchell, A. Hewitt, M. Kähönen, L. Pérusse, C. Bouchard, A. Tönjes, Y. Chen, C. Pennell, Trevor A. Mori, W. Lieb, A. Franke, C. Ohlsson, D. Mellström, Y. Cho, Hyejin Lee, Jian-Min Yuan, W. Koh, S. Rhee, J. Woo, I. Heid, K. Stark, H. Völzke, G. Homuth, M. Evans, A. Zonderman, O. Polašek, G. Pasterkamp, I. Hoefer, S. Redline, K. Pahkala, A. Oldehinkel, H. Snieder, G. Biino, R. Schmidt, H. Schmidt, Y. E. Chen, S. Bandinelli, G. Dedoussis, T. Thanaraj, S. Kardia, N. Kato, M. Schulze, G. Girotto, B. Jung, C. Böger, Peter K. Joshi, D. Bennett, P. D. De Jager, Xiangfeng Lu, Vasiliki Mamakou, Morris J. Brown, M. Caulfield, P. Munroe, Xiuqing Guo, M. Ciullo, J. Jonas, N. Samani, J. Kaprio, P. Pajukanta, L. Adair, Sonny A Bechayda, H. J. de Silva, A. R. Wickremasinghe, R. Krauss, Jer-Yuarn Wu, W. Zheng, A. D. den Hollander, D. Bharadwaj, A. Correa, James G. Wilson, L. Lind, C. Heng, A. Nelson, Y. Golightly, James F. Wilson, B. Penninx, Hyung-Lae Kim, J. Attia, R. Scott, D. Rao, D. Arnett, M. Walker, H. Koistinen, G. Chandak, C. Yajnik, J. Mercader, Teresa Tusié-Luna, C. Aguilar-Salinas, Clicerio González Villalpando, L. Orozco, M. Fornage, E. Tai, R. V. van Dam, T. Lehtimäki, N. Chaturvedi, Mitsuhiro Yokota, J. Liu, Dermot F. Reilly, A. McKnight, F. Kee, K. Jöckel, M. McCarthy, C. Palmer, V. Vitart, C. Hayward, E. Simonsick, C. V. van Duijn, F. Lu, J. Qu, H. Hishigaki, Xu Lin, W. März, E. Parra, M. Cruz, V. Gudnason, J. Tardif, G. Lettre, L. T. ’t Hart, P. Elders, S. Damrauer, M. Kumari, M. Kivimaki, P. van der Harst, T. Spector, R. Loos, M. Province, B. Psaty, I. Brandslund, P. Pramstaller, K. Christensen, S. Ripatti, E. Widén, H. Hakonarson, S. Grant, L. Kiemeney, J. de Graaf, M. Loeffler, F. Kronenberg, D. Gu, J. Erdmann, H. Schunkert, P. Franks, A. Linneberg, J. Jukema, A. Khera, M. Männikkö, M. Jarvelin, Z. Kutalik, F. Cucca, D. Mook-Kanamori, K. W. van Dijk, H. Watkins, D. Strachan, N. Grarup, P. Sever, N. Poulter, J. Rotter, T. Dantoft, F. Karpe, M. Neville, N. Timpson, Ching-Yu Cheng, T. Wong, C. Khor, C. Sabanayagam, A. Peters, C. Gieger, A. Hattersley, N. Pedersen, P. Magnusson, D. Boomsma, E. D. de Geus, L. Cupples, J. V. van Meurs, M. Ghanbari, P. Gordon-Larsen, Wei Huang, Y. J. Kim, Y. Tabara, N. Wareham, C. Langenberg, E. Zeggini, J. Kuusisto, M. Laakso, E. Ingelsson, G. Abecasis, J. Chambers, J. Kooner, P. D. de Vries, A. Morrison, K. North, M. Daviglus, P. Kraft, N. Martin, J. Whitfield, S. Abbas, D. Saleheen, R. Walters, M. Holmes, C. Black, Blair H. Smith, A. Justice, A. Baras, J. Buring, P. Ridker, D. Chasman, C. Kooperberg, Wei-Qi Wei, G. Jarvik, B. Namjou, M. Hayes, M. Ritchie, P. Jousilahti, V. Salomaa, K. Hveem, B. Åsvold, M. Kubo, Y. Kamatani, Y. Okada, Y. Murakami, U. Thorsteinsdóttir, K. Stefánsson, Y. Ho, J. Lynch, D. Rader, P. Tsao, Kyong‐Mi Chang, Kelly Cho +499 moresemanticscholar +1 more sourceSingle‐cell insights into the role of T cells in B‐cell malignancies
FEBS Letters, EarlyView.Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...Laura Llaó‐Cidwiley +1 more sourceGenetic diversity of local cattle*
Acta Biochimica Polonica, 2018 The Slovak Pinzgau breed faces the bottleneck effect and the loss of diversity due to unequal use of founders and significant population decline. Further population size reduction can lead to serious problems. High-throughput genotypes of 179 individuals were used to characterise genetic diversity and differentiation of Slovak Pinzgau, Austrian Pinzgau,Radovan Kasarda, Gábor Mészáros, Mojca Simčič, Ino Curik, Nina Moravčíková, Veronika Kukučková +5 moreopenaire +4 more sources
