Results 101 to 110 of about 1,556,760 (310)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

First report of Seville root-knot nematode, Meloidogyne hispanica (Nematoda: Meloidogynidae) in the USA and North America [PDF]

Journal of Nematology, 2021
Andrea M. Skantar, Zafar A. Handoo, Sergei A. Subbotin, Mihail R. Kantor, Paulo Vieira, Paula Agudelo, Maria N. Hult, Stephen Rogers   +7 more
doaj   +1 more source

A global strategy for the conservation and use of cacao genetic resources, as the Foundation for a sustainable cocoa economy [PDF]

, 2012
The future of the world cocoa economy depends on the availability of genetic diversity and the sustainable use of this broad genetic base to breed improved varieties. Decreasing cacao genetic diversity (in situ, on-farm and conserved in collections) is a
Cryer, N.C., Daymond, Andrew J., End, M.J., Engels, Johannes M.M., Eskes, Albertus, Gilmour, Martin, Lachenaud, Philippe, Laliberté, Brigitte, Phillips-Mora, Wilbert, Turnbull, Christ J., Umaharan, Pathmanathan, Weise, Stephan, Zhang, Dapeng   +12 more
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

New additions to the fungal species of Guyana

Studies in Fungi
DNA barcoding is today a standard method used for species identification, preferably in conjunction with supporting morphological data. Here, we employed DNA barcoding using the highly conserved nuclear ribosomal internal transcribed spacer (ITS) region ...
Frode Jacobsen, Carol Kelloff, Lisa A. Castlebury   +2 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Limited role of aquatic habitat complexity in mitigating the ecological impact of invasive bullfrogs on native amphibians

Global Ecology and Conservation
Spatial overlap in habitat use and structural habitat complexity can shape the ecological impact of biological invasions. Environmental conditions that mitigate these impacts can be exploited in nature-based conservation strategies aimed at damage ...
Jonathan Tibo, Rein Brys, Hans Jacquemyn, Charlotte Van Driessche, Teun Everts   +4 more
doaj   +1 more source

Structure and genetic diversity in wild and cultivated populations of Zapote mamey (Pouteria sapota, Sapotaceae) from southeastern Mexico: its putative domestication center [PDF]

, 2019
Tropical fruit trees are an important component of the human diet; however, little is known about their genetic diversity levels. Zapote mamey (Pouteria sapota) is a tree native to southeastern Mexico and Central America, and Mexico is the leading ...
Arias, Renee S., Blancarte-Jasso, Nassib H., Chepe-Cruz, Gabriel, Martínez-Castillo, Jaime, Nah-Chan, Noemí G., Ortiz-García, Matilde M.   +5 more
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source