Results 141 to 150 of about 5,291,009 (397)
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
, 2009 Human-made structures are increasingly found in marine coastal habitats. The aim of the present study was to explore whether urban coastal structures can affect the genetic variation of hard-bottom species.
Abbiati, Marco +4 more
core +1 more source
Evolutionary Applications, 2017 Genetic diversity underpins the ability of populations to persist and adapt to environmental changes. Substantial empirical data show that genetic diversity rapidly deteriorates in small and isolated populations due to genetic drift, leading to reduction
A. Pavlova +14 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin +14 more
wiley +1 more source
FACTORS DETERMINING CONJUGATION IN PARAMECIUM AURELIA II. GENETIC DIVERSITIES BETWEEN STOCKS OR RACES [PDF]
, 1936 T. M. Sonneborn, B M Cohen
openalex +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Molecular Oncology, EarlyView.Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park +6 more
wiley +1 more source
Genetic diversity of porcine sapoviruses
Veterinary Microbiology, 2007 Sapoviruses (SaVs) within the Caliciviridae family are an important cause of gastroenteritis in both humans and animals. Although the widespread occurrence of divergent human SaV strains has been reported, there have only been a few studies of porcine SaVs examining their genetic diversity.
Cheol Won Jeong +11 more
openaire +3 more sources
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
Molecular Oncology, EarlyView.We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi +26 more
wiley +1 more source
First report of Cactodera milleri Graney and Bird, 1990 from Colorado and Minnesota [PDF]
Journal of Nematology, 2021 Andrea M. Skantar +7 more
doaj +1 more source
Genetic Diversity in Pseudomonas syringae pv. maculicola Strains
Journal of Pure and Applied Microbiology, 2018 Pseudomonas syringae pv. maculicola (Psm) is a phytopathogen of a wide range of host plants from the cruciferae family, producing blight. Some strains infect Arabidopsis thaliana, whose genetic characteristics has made it a plant model for analyses of ...
Cesar Alvarez-Mejia +4 more
doaj +1 more source