Results 141 to 150 of about 1,359,813 (255)

Identification of selection signatures and genetic diversity in the sheep. [PDF]

Trop Anim Health Prod
Karabaş M, Yılmaz O.
europepmc   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Faroese sheep expand overall global ovine genetic diversity. [PDF]

BMC Genom Data
Hansen EK, Í Gerðinum JI, Våge DI, Mikalsen SO.   +3 more
europepmc   +1 more source

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

FEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang, Lynn Kee, Alexander Gont, Jalna Meens, Fraser G. Ferens, Meredith S. Irwin, Laurie Ailles, Scott A. Yuzwa, Claire M. Robinson, Michael Ohh   +9 more
wiley   +1 more source

Genetic Diversity and Metabolic Profile of Tibetan Medicinal Plant <i>Saussurea obvallata</i>. [PDF]

Genes (Basel)
Zhang S, Wang S, Wang S, Su H, De J.
europepmc   +1 more source

Maize Genetic Diversity: Utilization of Molecular Markers in Genetic Diversity

International Journal of Current Microbiology and Applied Sciences, 2020
Anand Kumar, Vivudh Pratap Singh
openaire   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Genetic diversity analysis and core germplasm construction of tea plants in Lu'an. [PDF]

BMC Plant Biol
Wang Y, Peng H, Tong X, Ding X, Song C, Ma T, Wang H, Wei W, Chen C, Zhu J, Liu D.   +10 more
europepmc   +1 more source

Downregulation of O‐GlcNAcylation enhances etoposide‐induced p53‐mediated apoptosis in HepG2 human liver cancer cells

FEBS Open Bio, EarlyView.
Etoposide, a topoisomerase II inhibitor, reduces O‐GlcNAcylation in HepG2 liver cancer cells. Further inhibition of O‐GlcNAc transferase by OSMI‐1 enhanced etoposide‐induced apoptosis, lowering the IC50 for viability and increasing the EC50 for cytotoxicity.
Jaehoon Lee, Gi‐Bang Koo, Jihye Park, Byung‐Cheol Han, Mijin Kwon, Seung‐Ho Lee   +5 more
wiley   +1 more source

Whole Genome Insights into Genetic Diversity, Introgression, and Adaptation of Hunan Cattle. [PDF]

Animals (Basel)
Li Y, Li J, Duan H, Sun A, Hu R, Gao S, Zhang B, Huang B, Lei C, Yi K.   +9 more
europepmc   +1 more source