Results 81 to 90 of about 92,865 (288)
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
How Symbiosis Can Guide Evolution [PDF]
, 1999 Hinton and Nowlan have demonstrated a model of how lifetime plasticity can guide evolution. They show how acquired traits change the shape of the reward landscape in which subsequent genetic variation takes place, and in so doing encourage the discovery ...
Jordan B. Pollack +3 more
core +1 more source
BMC Evolutionary Biology, 2010 Background Patterns of spatial variation in discrete phenotypic traits can be used to draw inferences about the adaptive significance of traits and evolutionary processes, especially when compared to patterns of neutral genetic variation.
Runemark Anna +4 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Stability and task complexity: a neural network model of genetic assimilation [PDF]
, 2002 Since Hinton and Nowlan introduced the Baldwin effect to the evolutionary computation community, agent-based studies of genetic assimilation have uncovered many details of the dynamic processes involved.
Geard, N, Wiles, J, Watson, J
core
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Phenotypic divergence in widespread plants : genetic drift, selection and plasticity [PDF]
, 2011 This thesis presents studies that describe and explain phenotypic differentiation within several alpine plant species. The key elements that are addressed are threefold: (1) effects of neutral genetic drift, natural selection and phenotypic plasticity on
Scheepens, Johannes Fredericus
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The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
A population genetics model of marker-assisted selection [PDF]
, 1997 A deterministic two-loci model was developed to predict genetic response to marker-assisted selection (MAS) in one generation and in multiple generations.
Luo, Z. W. +4 more
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