Results 61 to 70 of about 92,865 (288)
Does gene flow aggravate or alleviate maladaptation to environmental stress in small populations?
Evolutionary Applications, 2019 Environmental change can expose populations to unfamiliar stressors, and maladaptive responses to those stressors may result in population declines or extirpation.
Sarah W. Fitzpatrick, Brendan N. Reid
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Polygenic Adaptation in a Population of Finite Size
Entropy, 2020 Polygenic adaptation in response to selection on quantitative traits has become an important topic in evolutionary biology. Here we review the recent literature on models of polygenic adaptation.
Wolfgang Stephan, Sona John
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Hsp90-Induced Evolution: Adaptationist, Neutralist, and Developmentalist Scenarios [PDF]
, 2008 Recent work on the heat-shock protein Hsp90 by Rutherford and Lindquist (1998) has been included among the pieces of evidence taken to show the essential role of developmental processes in evolution; Hsp90 acts as a buffer against phenotypic variation ...
Millstein, Roberta L.
core
Recent evolutionary history predicts population but not ecosystem‐level patterns
Ecology and Evolution, 2019 In the face of rapid anthropogenic environmental change, it is increasingly important to understand how ecological and evolutionary interactions affect the persistence of natural populations.
Madison L. Miller +2 more
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Structure and genetic variability in Nellore (Bos indicus) cattle by pedigree analysis
Genetics and Molecular Biology, 2006 Parameters based on the probability of gene origin were used to describe the genetic variability in strains of Nellore and polled Nellore (Bos indicus) cattle that participated in the Program for Genetic Improvement of the Nellore Breed (Programa de ...
Pedro Alejandro Vozzi +4 more
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Genetic drift and polygenic inheritance [PDF]
American Journal of Physical Anthropology, 1972 AbstractThe interaction of random gene drift and selection was studied by computer simulation for two quantitative traits, which were considered to approximate stature and skin color differences in human populations. The expected effects of gene drift, fixation of alleles and reduction of genotypic and phenotypic variances, were found in the simulation.
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The Genetic Drift Inventory: A Tool for Measuring What Advanced Undergraduates Have Mastered about Genetic Drift [PDF]
, 2014 Understanding genetic drift is crucial for a comprehensive understanding of biology, yet it is difficult to learn because it combines the conceptual challenges of both evolution and randomness.
Mead, Louise S. +6 more
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Random genetic drift in a cline [PDF]
Proceedings of the National Academy of Sciences, 1978 A diffusion model is derived for random genetic drift in a cline. The monoecious organism occupies an unbounded linear habitat with constant, uniform population density. Migration is homogeneous, symmetric, and independent of genotype. The analysis applies to a single diallelic locus without dominance or mutation.
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