Results 41 to 50 of about 92,865 (288)

Genetic Assimilation and Canalisation in the Baldwin Effect [PDF]

open access: yes, 2005
The Baldwin Effect indicates that individually learned behaviours acquired during an organism’s lifetime can influence the evolutionary path taken by a population, without any direct Lamarckian transfer of traits from phenotype to genotype.
Richard A. Watson   +3 more
core   +1 more source

Change in genetic size of small-closed populations: lessons from a domestic mammal population

open access: yesGenetics and Molecular Biology, 2010
The aim of this study was to monitor changes in genetic size of a small-closed population of Iranian Zandi sheep, by using pedigree information from animals born between 1991 and 2005.
Farhad Ghafouri-Kesbi
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Stochastic Evolutionary Dynamics: Drift vs. Draft [PDF]

open access: yes, 2004
In a small handful of papers in theoretical population genetics, John Gillespie argues that a new stochastic process he calls "genetic draft" is evolutionarily more significant than genetic drift. This case study of chance in evolution explores Gillespie'
Skipper, Robert
core  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Frequent Genetic Mismatch between Vaccine Strains and Circulating Seasonal Influenza Viruses, Hong Kong, China, 1996–2012

open access: yesEmerging Infectious Diseases, 2018
The World Health Organization selects influenza vaccine compositions biannually to cater to peaks in temperate regions. In tropical and subtropical regions, where influenza seasonality varies and epidemics can occur year-round, the choice of vaccine ...
Martin C.W. Chan   +9 more
doaj   +1 more source

It's Okay to Call Genetic Drift a “Force” [PDF]

open access: yes, 2012
One hotly debated philosophical question in the analysis of evolutionary theory concerns whether or not evolution and the various factors which constitute it (selection, drift, mutation, and so on) may profitably be considered to be “forces” in the ...
Pence, Charles H.
core   +7 more sources

Phenotypic stasis with genetic divergence

open access: yesPeer Community Journal, 2023
Whether or not genetic divergence in the short-term of tens to hundreds of generations is compatible with phenotypic stasis remains a relatively unexplored problem.
Mallard, François   +5 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Concepts of Drift and Selection in “The Great Snail Debate” of the 1950s and Early 1960s [PDF]

open access: yes, 2007
Recently, much philosophical discussion has centered on the best way to characterize the concepts of random drift and natural selection, and, in particular, on the question of whether selection and drift can be conceptually distinguished (Beatty 1984 ...
Millstein, Roberta L.
core  

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