Results 51 to 60 of about 234,175 (326)

Migration and Genetic Drift in Human Populations [PDF]

Evolution, 1986
In humans and many other species, mortality is concentrated early in the life cycle, and is low during the ages of dispersal and reproduction. Yet precisely the opposite is assumed by classical population-genetics models of migration and genetic drift. We introduce a model in which population regulation occurs before migration.
Alan R, Rogers, Henry C, Harpending
openaire   +2 more sources

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine, Ofélie Trudeau‐Ferrin, Caroline Laverdière, Patrick Hamel, Rosanne Superstein, Bénédicte Koukoui, Carole Provost, Paul C. Nathan, Vijay Ramaswamy, Furqan Shaikh, Brenda Gallie, Ashwin Mallipatna, Stephanie Kletke, Helen Dimaras, Hallie Coltin   +14 more
wiley   +1 more source

Population genetic structure in a self‐compatible hermaphroditic snail is driven by drift independently of its contemporary mating system

Ecology and Evolution
Genetic drift, gene flow, and natural selection commonly influence population genetic diversity. In populations of self‐compatible hermaphrodites, the mating system (e.g., self‐fertilization) further reduces individual heterozygosity.
Cansu Çetin, Jukka Jokela, Philine G. D. Feulner, Tamara Schlegel, Nadine Tardent, Otto Seppälä   +5 more
doaj   +1 more source

Frequent Genetic Mismatch between Vaccine Strains and Circulating Seasonal Influenza Viruses, Hong Kong, China, 1996–2012

Emerging Infectious Diseases, 2018
The World Health Organization selects influenza vaccine compositions biannually to cater to peaks in temperate regions. In tropical and subtropical regions, where influenza seasonality varies and epidemics can occur year-round, the choice of vaccine ...
Martin C.W. Chan, Maggie H. Wang, Zigui Chen, David S.C. Hui, Angela K. Kwok, Apple C.M. Yeung, Kun M. Liu, Yun Kit Yeoh, Nelson Lee, Paul K.S. Chan   +9 more
doaj   +1 more source

Phenotypic stasis with genetic divergence

Peer Community Journal, 2023
Whether or not genetic divergence in the short-term of tens to hundreds of generations is compatible with phenotypic stasis remains a relatively unexplored problem.
Mallard, François, Noble, Luke, Guzella, Thiago, Afonso, Bruno, Baer, Charles F., Teotónio, Henrique   +5 more
doaj   +1 more source

Directional selection effects on patterns of phenotypic (co)variation in wild populations. [PDF]

, 2016
Phenotypic (co)variation is a prerequisite for evolutionary change, and understanding how (co)variation evolves is of crucial importance to the biological sciences.
Assis, APA, Hubbe, A, Marroig, G, Patton, JL   +3 more
core   +3 more sources

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

Gene surfing [PDF]

, 2007
Spatially resolved genetic data is increasingly used to reconstruct the migrational history of species. To assist such inference, we study, by means of simulations and analytical methods, the dynamics of neutral gene frequencies in a population ...
Allee, Austerlitz, Austerlitz, Brunet, Brunet, Cavalli-Sforza, Courchamp, Crow, Currat, Dahmen, David R. Nelson, Desai, Doering, Edmonds, Fisher, Gaggiotti, Hartl, Hewitt, Hewitt, Kingman, Klopfstein, Le Corre, Liu, Moran, Murray, Nagylaki, Nagylaki, Nagylaki, Nichols, Notohara, Oskar Hallatschek, Panja, Pease, Phillips, Pulliam, Ramachandran, Rosenberg, Rouzine, Templeton, Tsimring, van Kampen, van Saarloos, Vlad, Wilkins   +43 more
core   +2 more sources

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

The Genetic Drift of Indonesian Avian Influenza A H5N1 Viruses During 2003-2008

Microbiology Indonesia, 2011
The avian influenza A H5N1 outbreaks started in 2003 and Indonesia introduced a vaccination campaign in 2004 to control the disease. In 2007, anecdotal reports about reduced vaccine effectiveness were received from commercial farmers.
NI LUH PUTU INDI DHARMAYANTI, GINA SAMAAN, FERA IBRAHIM, RISA INDRIANI, . DARMINTO, AMIN SOEBANDRIO   +5 more
doaj   +1 more source